Molecular Cloning of a Novel Apoptosis-Related Gene, Human Nap1 (NCKAP1), and Its Possible Relation to Alzheimer Disease

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1991 • 4,533 citations

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1995 • 3,985 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

1986 • 3,231 citations

Candidate Gene for the Chromosome 1 Familial Alzheimer's Disease Locus

1995 • 2,548 citations

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1995 • 2,028 citations

A knowledge base for predicting protein localization sites in eukaryotic cells

1992 • 1,518 citations

Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo

1996 • 1,467 citations

Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1

1996 • 1,439 citations

A mutation in the Amyloid Precursor Protein Associated with Hereditary Alzheimer's Disease

1991 • 1,121 citations

Apoptosis is induced by beta-amyloid in cultured central nervous system neurons.

1993 • 1,035 citations

Genetic Linkage Evidence for a Familial Alzheimer's Disease Locus on Chromosome 14

1992 • 941 citations

A Familial Alzheimer's Disease Locus on Chromosome 1

1995 • 810 citations

Cellular processing of β-amyloid precursor protein and the genesis of amyloid β-peptide

1993 • 809 citations

Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation

1999 • 777 citations

Apolipoprotein E and Alzheimer disease.

1995 • 697 citations

Immunohistochemical evidence for apoptosis in Alzheimerʼs disease

1994 • 569 citations

Evidence for Apoptotic Cell Death in Alzheimer's Disease

1995 • 482 citations

2,3,7,8-Tetrachlorodibenzo- p -Dioxin Kills Immature Thymocytes by Ca ²⁺ -Mediated Endonuclease Activation

1988 • 460 citations

Alzheimer amyloid protein precursor complexes with brain GTP-binding protein Go

1993 • 430 citations

A potential role for apoptosis in neurodegeneration and Alzheimer's disease

1995 • 382 citations

A system for characterizing cellular and molecular events in programmed neuronal cell death

1993 • 267 citations

PARASEXUAL APPROACHES TO THE GENETICS OF MAN

1975 • 203 citations

Apoptotic Cell Death Induced by β‐Amyloid_1–42 Peptide Is Cell Type Dependent

1995 • 202 citations

Fluorescent differential display: Arbitrarily primed RT‐PCR fingerprinting on an automated DNA sequencer

1994 • 194 citations

Biology of Aβ Amyloid in Alzheimer's Disease

1997 • 187 citations

β-Amyloid induces apoptosis in human-derived neurotypic SH-SY5Y cells

1996 • 151 citations

High-density cDNA filter analysis: a novel approach for large-scale, quantitative analysis of gene expression

1995 • 123 citations

High-Resolution Cytogenetic Mapping of 342 New Cosmid Markers Including 43 RFLP Markers on Human Chromosome 17 by Fluorescence in Situ Hybridization

1993 • 107 citations

Molecular Cloning of p125Nap1, a Protein That Associates with an SH3 Domain of Nck

1996 • 64 citations

Regulation of Brain G-protein Go by Alzheimer's Disease Gene Presenilin-1

1998 • 58 citations

Interaction of Nck-associated protein 1 with activated GTP-binding protein Rac

1997 • 52 citations

The HEM Proteins: A Novel Family of Tissue-specific Transmembrane Proteins Expressed from Invertebrates Through Mammals with an Essential Function in Oogenesis

1995 • 39 citations

Molecular biology of brain aging and neurodegenerative disorders

1996 • 24 citations

Hem-1, a potential membrane protein, with expression restricted to blood cells

1991 • 21 citations

Carbachol enhances forskolin-stimulated cyclic AMP accumulation via activation of calmodulin system in human neuroblastoma SH-SY5Y cells

1991 • 15 citations

Increased Cu/Zn superoxide dismutase-like immunoreactivity in the swollen axons of rats intoxicated chronically with β,β′-iminodipropionitrile

1995 • 9 citations

Cloning and characterization of a cDNA specific for bovine retina

1986 • 2 citations