Cis-diamminedichloroplatinum(II) Induced Distortion of a Single and Double Stranded Deoxydecanucleosidenona-phosphate Studied by Nuclear Magnetic Resonance

Elucidation of cross relaxation in liquids by two-dimensional N.M.R. spectroscopy

1980 • 1,490 citations

Adducts of the antitumor drug cis-diamminedichloroplatinum(II) with DNA: formation, identification, and quantitation

1985 • 994 citations

Experimental techniques of two-dimensional correlated spectroscopy

1980 • 598 citations

The Mechanism of Action of Antitumor Platinum Compounds

1979 • 408 citations

Binding of cis - and trans -Dichlorodiammineplatinum(II) to DNA: Evidence for Unwinding and Shortening of the Double Helix

1979 • 254 citations

Cross-linking of Complementary Strands of DNA in Mammalian Cells by Antitumour Platinum Compounds

1972 • 245 citations

Sequential resonance assignments in DNA proton NMR spectra by two-dimensional NOE spectroscopy

1983 • 236 citations

Modifications of the DNA secondary structure upon platinum binding: a proposed model

1978 • 170 citations

Detection and quantification of adducts formed upon interaction of diamminedichloroplatinum (II) with DNA, by anion-exchange chromatography after enzymatic degradation

1982 • 150 citations

Specific binding of antitumour drug cis-Pt(NH3)2Cl2 to DNA rich in guanine and cytosine

1974 • 143 citations

A new approach to the synthesis of phosphotriester intermediates of nucleosides and nucleic acids

1981 • 141 citations

Conformational analysis of the adductcis[Pt(NH₃)₂{d(GpG)}]⁺in aqueous solution. A high field (500–300 MHz) nuclear magnetic resonance investigation

1982 • 125 citations

Base-pair substitution hotspots in GAG and GCG nucleotide sequences in Escherichia coli K-12 induced by cis-diamminedichloroplatinum (II).

1981 • 125 citations

Temperature dependence of the phosphorus-31 chemical shifts of nucleic acids. A probe of phosphate ester torsional conformations

1976 • 119 citations

Use of two-dimensional NMR in the study of a double-stranded DNA decamer

1982 • 103 citations

cis-Diamminedichloroplatinum(II) induced distortion in a double-helical DNA fragment

1984 • 86 citations

Conformational Characteristics of the Trinucleoside Diphosphate dApdApdA and Its Constituents from Nuclear Magnetic Resonance and Circular Dichroism Studies

1980 • 85 citations

The reaction of 14C-labelled platinum ethylenediamine dichloride with nucleic acid constituents

1973 • 73 citations

Conformational Analysis of a Hybrid DNA-RNA Double Helical Oligonucleotide in Aqueous Solution: d(CG)r(CG)d(CG) Studied by 1D- and 2D-¹H NMR Spectroscopy

1983 • 69 citations

A ¹H and ³¹P NMR study of cis‐Pt(NH₃)₂ [d(CpGpG)‐N7 (2),N7 (3)] The influence of a 5′‐terminal cytosine, on the structure of the cis‐Pt(NH₃)₂ [d(GpG)‐N7,N7] instrastrand cross‐link

1985 • 58 citations

Platinum-DNA crosslinking: platinum antitumor drug interactions with native lambda bacteriophage DNA studied using a restriction endonuclease

1978 • 54 citations

A d(GpG)-platinated oligonucleotide can form a duplex with a complementary strand

1984 • 51 citations

Discrimination Between A-type and B-type Conformations of Double Helical Nucleic Acid Fragments in Solution by Means of Two-dimensional Nuclear Overhauser Experiments

1984 • 51 citations

Sequence analysis of synthetic oligonucleotides by high-performance liquid anion-exchange chromatography

1977 • 39 citations

A conformational study of nucleic acid phosphate ester bonds using phosphorus-31 nuclear magnetic resonance¹

1979 • 38 citations

DNA fragment conformations. A 1H-NMR conformational analysis of the d(G-G)-chelated platinum-oligonucleotide d(A-T-G-G)cisPt

1984 • 33 citations

Chelation of cis-Pt(NH3)2Cl2 by the deoxynucleotide d(CCGG)

1981 • 33 citations

Interaction of platinum compounds with short oligodeoxynucleotides containing guanine and cytosine

1983 • 32 citations

An effective method for the assignment of ³¹P‐nmr resonance(s) of oligonucleotides

1982 • 31 citations

A phosphorus NMR study of the reaction products of cis‐diamminedichloroplatinum (II) with a double‐helical oligonucleotide and with DNA

1984 • 27 citations

Conformational analysis of the single‐helical DNA fragment d(T‐A‐A‐T) in aqueous solution

1984 • 27 citations

Cis-diamminedichloroplatinum(II) modified DNA stimulates far greater levels of S1 nuclease sensitive regions than does the modification produced by the trans- isomer

1982 • 26 citations

Evidence for similar structural changes on binding of platinum anti‐tumor agents to DNA and nucleosomes

1984 • 24 citations

Diamagnetic metal species that induce pronounced changes in the phosphorus NMR spectrum of DNA

1982 • 23 citations

Unwinding in an undecamer double-helical DNA fragment, after binding of cis-diamminedichloroplatinum to a d(-GpTpG-) sequence

1985 • 21 citations

Deleted Work

1955 • 0 citations