Biology of Hepatitis B Virus

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Method for detection of specific RNAs in agarose gels by transfer to diazobenzyloxymethyl-paper and hybridization with DNA probes.

1977 • 2,233 citations

Nucleotide sequence of bacteriophage G4 DNA

1978 • 2,137 citations

Nucleotide sequence of bacteriophage φX174 DNA

1977 • 1,475 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

A "New" Antigen in Leukemia Sera

1965 • 1,302 citations

Changes in size and secondary structure of the ribosomal transcription unit during vertebrate evolution

1975 • 1,188 citations

Hepatitis B Vaccine

1980 • 1,107 citations

Complete nucleotide sequence of SV40 DNA

1978 • 1,050 citations

Vertical Transmission of Hepatitis B Antigen in Taiwan

1975 • 1,022 citations

Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli

1979 • 992 citations

Immunofluorescence detection of new antigen-antibody system (delta/anti-delta) associated to hepatitis B virus in liver and in serum of HBsAg carriers.

1977 • 964 citations

The Genome of Simian Virus 40

1978 • 948 citations

DNA Polymerase Associated with Human Hepatitis B Antigen

1973 • 741 citations

CONNEXIONS AND FUNCTIONS OF FRONTAL LOBES

1947 • 685 citations

A virus similar to human hepatitis B virus associated with hepatitis and hepatoma in woodchucks.

1978 • 657 citations

Presence of integrated hepatitis B virus DNA sequences in cellular DNA of human hepatocellular carcinoma

1980 • 610 citations

Hepatitis B virus genes and their expression in E. coli

1979 • 584 citations

Virus of Pekin ducks with structural and biological relatedness to human hepatitis B virus

1980 • 506 citations

The structure and evolution of the two nonallelic rat preproinsulin genes

1979 • 500 citations

Transmission of the Hepatitis B Virus-Associated Delta Antigen to Chimpanzees

1980 • 486 citations

The primary structure of rabbit β-globin mRNA as determined from cloned DNA

1977 • 428 citations

Conservation of the primary structure at the 3′ end of 18S rRNA from eucaryotic cells

1978 • 427 citations

delta Agent: association of delta antigen with hepatitis B surface antigen and RNA in serum of delta-infected chimpanzees.

1980 • 423 citations

Chemically synthesized peptides predicted from the nucleotide sequence of the hepatitis B virus genome elicit antibodies reactive with the native envelope protein of Dane particles.

1981 • 412 citations

Coincidence of the promoter and capped 5′ terminus of RNA from the adenovirus 2 major late transcription unit

1978 • 390 citations

A virus in Beechey ground squirrels that is related to hepatitis B virus of humans.

1980 • 367 citations

State of hepatitis B virus DNA in hepatocytes of patients with hepatitis B surface antigen-positive and -negative liver diseases.

1981 • 351 citations

Organisation and sequences at the 5′ end of a cloned complete ovalbumin gene

1979 • 340 citations

HBeAg and anti‐hbe detection by radioimmunoassay: Correlation with vertical transmission of hepatitis B virus in Taiwan

1979 • 335 citations

Genome of hepatitis B virus: restriction enzyme cleavage and structure of DNA extracted from Dane particles.

1975 • 309 citations

Nucleotide sequence of the gene coding for the major protein of hepatitis B virus surface antigen

1979 • 298 citations

Integration of hepatitis B virus sequences and their expression in a human hepatoma cell

1980 • 291 citations

DNA of a Human Hepatitis B Virus Candidate

1974 • 270 citations

Viral Hepatitis, Type B

1979 • 268 citations

Hepatitis B virus contains protein attached to the 5′ terminus of its complete DNA strand

1980 • 248 citations

Identification of integrated hepatitis B virus DNA and expression of viral RNA in an HBsAg-producing human hepatocellular carcinoma cell line

1980 • 247 citations

Expression in Escherichia coli of hepatitis B virus DNA sequences cloned in plasmid pBR322

1979 • 239 citations

Excretion of hepatitis B surface antigen particles from mouse cells transformed with cloned viral DNA.

1980 • 232 citations

Demonstration of Hepatitis B e Antigen in the Core of Dane Particles

1979 • 204 citations

The hepatitis B virus-associated delta antigen: isolation from liver, development of solid-phase radioimmunoassays for delta antigen and anti-delta and partial characterization of delta antigen.

1980 • 197 citations

AUG is the only recognisable signal sequence in the 5′ non-coding regions of eukaryotic mRNA

1978 • 172 citations

Cloning in Escherichia coli and physical structure of hepatitis B virion DNA.

1979 • 171 citations

State of hepatitis B viral DNA in a human hepatoma cell line

1980 • 164 citations

Hepatitis B subunit vaccine

1975 • 163 citations

Expression of the hepatitis B virus surface antigen gene in cell culture by using a simian virus 40 vector

1981 • 157 citations

Purified and inactivated human hepatitis B vaccine

1975 • 138 citations

Recent advances in the study of the epidemiology of hepatitis B.

1975 • 122 citations

Cloning and endonuclease mapping of the hepatitis B viral genome

1979 • 120 citations

Protein Kinase Activity in Hepatitis B Virus

1980 • 112 citations

Australia Antigen (Hepatitis B Antigen): A Conformational Antigen Dependent on Disulfide Bonds

1972 • 106 citations

Complete 3′ noncoding region sequences of rabbit and human β-globin messenger RNAs

1977 • 106 citations

THE GENOME OF HEPATITIS B VIRUS

1977 • 105 citations

Partial amino acid sequence of two major component polypeptides of hepatitis B surface antigen.

1977 • 103 citations

Serological relationship of woodchuck hepatitis virus to human hepatitis B virus

1979 • 99 citations

Isolation, characterization, and comparison of recombinant DNAs derived from genomes of human hepatitis B virus and woodchuck hepatitis virus.

1980 • 94 citations

Structure of hepatitis B surface antigen. Correlation of subtype with amino acid sequence and location of the carbohydrate moiety.

1982 • 91 citations

Structure of hepatitis B Dane particle DNA before and after the Dane particle DNA polymerase reaction

1977 • 86 citations

Biosynthesis of hepatitis B virus surface antigen in Escherichia coli

1980 • 86 citations

A 49,000-dalton polypeptide bearing all antigenic determinants and full immunogenicity of 22-nm hepatitis B surface antigen particles.

1980 • 81 citations

Polypeptides of hepatitis B virus surface antigen produced by a hepatoma cell line

1979 • 80 citations

Hepatitis B Viral DNA Molecules Have Cohesive Ends

1979 • 79 citations

Localization on the viral genome and nucleotide sequence of the gene coding for the two major polypeptides of the Hepatitis B surface antigen (HBs Ag)

1979 • 78 citations

Expression of cloned hepatitis B virus DNA in human cell cultures.

1980 • 77 citations

Hepatitis-associated Australia antigen. Protein, peptides and amine acid composition of purified antigen with its use in determining sensitivity of the hemagglutination test.

1972 • 67 citations

Restriction endonuclease cleavage map and location of unique features of the DNA of hepatitis B virus, subtype adw2.

1979 • 66 citations

Studies on a protamine (galline) from fowl sperm. 3. The total amino acid sequence of intact galline molecule.

1976 • 65 citations

Integrated Genomes of Animal Viruses

1980 • 64 citations

Host specificity of a serum marker for hepatitis B: evidence that "e antigen" has the properties of an immunoglobulin.

1977 • 61 citations

Duality of hepatitis B e antigen in serum of persons infected with hepatitis B virus: evidence for the nonidentity of e antigen with immunoglobulins.

1978 • 60 citations

Zum Thema: Hepatitis und Bluttransfusion¹

1955 • 54 citations

STUDIES ON A PROTAMINE (GALLINE) FROM FOWL SPERM.

1976 • 52 citations

GENETIC VARIATION AMONG HEPATITIS B AND RELATED VIRUSES*

1980 • 51 citations

Immunochemistry of Hepatitis B Surface Antigen (HBsAg): Preparation and Characterization of Antibodies to the Constituent Polypeptides

1975 • 47 citations

Chronic hepatitis in chimpanzee carriers of hepatitis B virus: morphologic, immunologic, and viral DNA studies.

1980 • 45 citations

Hepatitis-Associated Australia Antigen. Protein, Peptides and Amino Acid Composition of Purified Antigen with Its Use in Determining Sensitivity of the Hemagglutination Test

1972 • 42 citations

Specific cleavage of tryptophyl peptide bonds with periodate in sperm whale myoglobin

1967 • 41 citations

Reduction and Reoxidation of Australia Antigen: Loss and Reconstitution of Particle Structure and Antigenicity

1972 • 40 citations

Carbohydrates in Hepatitis B Antigen

1973 • 38 citations

Alteration of Hepatitis B Antigen (HB Ag) Determinants by Reduction and Alkylation

1973 • 36 citations

The Labelling of Galactose Residues in Hepatitis B Surface Antigen Glycoprotein

1978 • 35 citations

INTEGRATOR ENZYME HYPOTHESIS FOR REPLICATION OF HEPATITIS-B VIRUS

1975 • 33 citations

Glycoproteins Associated with Hepatitis B Antigen

1973 • 32 citations

Serotypes of hepatitis B antigen (HBS Ag): the problem of ???new??? determinants, as exemplified by ???t???

1975 • 31 citations

Hepatitis B surface antigen polypeptides: artifactual bands in sodium dodecyl sulfate-polyacrylamide gel electrophoresis caused by aggregation

1980 • 27 citations

Hepatitis B "e" Antigen: An Apparent Association with Lactate Dehydrogenase Isozyme-5

1977 • 26 citations

Release of e antigen from a Dane particle-rich preparation of hepatitis B virus

1977 • 25 citations

Antigenic Relationship of a Hepatitis B Surface Antigen-derived Polypeptide and Human Serum Albumin

1980 • 24 citations

BLOOD-LEAD LEVELS, BEHAVIOUR, AND INTELLIGENCE

1974 • 23 citations

Association of Hepatitis B e-Antigen (HBeAg) Determinants with the Core of Dane Particles

1979 • 21 citations

Carbohydrate Composition of Hepatitis B Surface Antigen

1977 • 18 citations

Tryptic Cleavage of Antibody Binding Sites from Hepatitis B Surface Antigen Particles

1976 • 15 citations

Vertical Transmission of Hepatitis B

1986 • 13 citations

[Cloning of the hepatitis B virus genome in Escherichia coli].

1978 • 10 citations

Glycopeptide Composition of Hepatitis B Surface Antigen

1980 • 10 citations

Oncogenic potential of new viral vaccines

1978 • 8 citations

The Specific Reduction of a and d Antigenic Determinants after Periodate Treatment of Hepatitis B Surface Antigen (HBsAg)

1978 • 8 citations

Overlapping Genes in Bacteriophages ϕ X174 and G4

1978 • 7 citations

The a(w) Subdeterminants

2015 • 7 citations

Tolerance to hepatitis B antigen: A hypothesis for its termination with ‘immune - RNA’

1974 • 5 citations

Kinetics of HBs antigen in man.

1975 • 5 citations

Structure and activity of hepatitis B antigen (HBAg). 1. Studies on some conformational aspects and chemical modification of hepatitis B antigen.

1974 • 5 citations

Deleted Work

1955 • 0 citations