Identification of a point mutation in the thyrotropin receptor of the hyt/hyt hypothyroid mouse.

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Site-directed mutagenesis of virtually any plasmid by eliminating a unique site

1992 • 1,089 citations

Two G Protein Oncogenes in Human Endocrine Tumors

1990 • 1,038 citations

Sequence Alignment of the G-Protein Coupled Receptor Superfamily

1992 • 847 citations

The SWISS-PROT protein sequence data bank

1992 • 530 citations

Molecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptor

1989 • 523 citations

Mutation in the Gene Encoding the Stimulatory G Protein of Adenylate Cyclase in Albright's Hereditary Osteodystrophy

1990 • 402 citations

The Lutropin/Choriogonadotropin Receptor… 4 Years Later*

1993 • 394 citations

Mutation spectrum of the rhodopsin gene among patients with autosomal dominant retinitis pigmentosa.

1991 • 364 citations

Molecular identification of the gene responsible for congenital nephrogenic diabetes insipidus

1992 • 331 citations

Cloning, chromosomal assignment, and regulation of the rat thyrotropin receptor: expression of the gene is regulated by thyrotropin, agents that increase cAMP levels, and thyroid autoantibodies.

1990 • 225 citations

Rhodopsin: structure, function, and genetics

1992 • 222 citations

The thyrotropin receptor 25 years after its discovery: new insight after its molecular cloning.

1992 • 217 citations

Autosomal dominant retinitis pigmentosa: Four new mutations in rhodopsin, one of them in the retinal attachment site

1991 • 166 citations

Functional role of proline and tryptophan residues highly conserved among G protein-coupled receptors studied by mutational analysis of the m3 muscarinic receptor.

1993 • 165 citations

Inherited Primary Hypothyroidism in Mice

1981 • 161 citations

Functional Consequences of Proline Mutations in the Cytoplasmic and Transmembrane Sectors of the Ca2+-ATPase of Sarcoplasmic Reticulum

1989 • 157 citations

Biochemical characterization of three stimulatory GTP-binding proteins. The large and small forms of Gs and the olfactory-specific G-protein, Golf.

1990 • 145 citations

Three-dimensional modelling of G protein-linked receptors

1990 • 133 citations

Human tritanopia associated with two amino acid substitutions in the blue-sensitive opsin.

1992 • 99 citations

Transient Neonatal Hypothyroidism: Characterization of Maternal Antibodies to the Thyrotropin Receptor*

1990 • 85 citations

Characterization of the 5'-flanking region of the rat thyrotropin receptor gene.

1992 • 84 citations

Asp383 in the second transmembrane domain of the lutropin receptor is important for high affinity hormone binding and cAMP production

1991 • 83 citations

Congenital Hypothyroidism with Impaired Thyroid Response to Thyrotropin

1968 • 75 citations

Evaluation and Characterization of the hyt/hyt Hypothyroid Mouse

1989 • 57 citations

Thyroid Hormone Control of Brain and Motor Development: Molecular, Neuroanatomical, and Behavioral Studies

1991 • 55 citations

Studies on multiple thyroid cell membrane-directed antibodies in Graves' disease.

1985 • 48 citations

Congenital Hypothyroidism Associated with Thyrotropin Unresponsiveness and Thyroid Cell Membrane Alterations

1980 • 45 citations

The Effects of Congenital Hypothyroidism Using the hyt/hyt Mouse on Locomotor Activity and Learned Behavior

1993 • 37 citations

Cloning, sequencing and tissue distribution of a candidate G protein‐coupled receptor from rat pituitary gland

1991 • 30 citations

Molecular genetics of the thyrotropin receptor

1991 • 25 citations

Nucleotide sequence of the dog thyrotropin receptor cDNA

1989 • 13 citations

Brain development in dwarf mice

1988 • 10 citations