Role for topoisomerases in the release of DNA into the detergent-soluble fraction of eukaryotic cells.

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

1985 • 2,298 citations

DNA TOPOISOMERASES

1985 • 1,524 citations

DNA Topoisomerases

1981 • 977 citations

DNA topoisomerase II is required at the time of mitosis in yeast

1985 • 747 citations

Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide.

1984 • 559 citations

Role of topoisomerase II in mediating epipodophyllotoxin-induced DNA cleavage.

1984 • 463 citations

Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4'-(9-acridinylamino)methanesulfon-m-anisidide and adriamycin

1981 • 382 citations

DNA Topoisomerases-Enzymes that Catalyse the Breaking and Rejoining of DNA

1983 • 216 citations

Superhelical Escherichia coli DNA: Relaxation by coumermycin

1978 • 203 citations

Comparison of cytotoxicity and DNA breakage activity of congeners of podophyllotoxin including VP16-213 and VM26: a quantitative structure-activity relationship

1984 • 188 citations

Mechanisms of DNA replication and recombination

1984 • 187 citations

Dependence of mammalian DNA replication on DNA supercoiling II. Effects of novobiocin on DNA synthesis in Chinese hamster ovary cells

1979 • 114 citations

DNA topoisomerases

1980 • 91 citations

Novobiocin inhibition of simian virus 40 DNA replication

1980 • 85 citations

The Association of Deoxyribonucleic Acid with Liver Microsomes

1969 • 60 citations

Characterization of DNA excreted from phytohemagglutinin-stimulated lymphocytes.

1976 • 60 citations

Physical properties of cytoplasmic membrane-associated DNA

1973 • 56 citations

Membrane transport by murine lymphocytes. I. A rapid sampling technique as applied to the adenosine and thymidine systems.

1976 • 55 citations

ts A1S9 locus in mouse L cells may encode a novobiocin binding protein that is required for DNA topoisomerase II activity.

1983 • 38 citations

Novobiocin-mediated inhibition of polymerization and ligation of DNA in vitro

1984 • 12 citations

Characterization of rapidly labeled detergent-soluble DNA in murine splenocytes

1984 • 6 citations

Incorporation of 3H-Labeled Nucleosides and 3H-Labeled Deoxynucleosides into Detergent Soluble DNA

1985 • 2 citations

Kinetics of thymidine incorporation into detergent-soluble DNA of mouse lymphocytes.

1984 • 2 citations