Covalent modification and active site-directed inactivation of a low molecular weight phosphotyrosyl protein phosphatase

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

1989 • 2,518 citations

A pharmacokinetic analysis program (multi) for microcomputer.

1981 • 2,465 citations

PROTEIN SERINE/THREONINE KINASES

1987 • 1,457 citations

Protein Tyrosine Phosphatases: A Diverse Family of Intracellular and Transmembrane Enzymes

1991 • 973 citations

[41] Modification of histidyl residues in proteins by diethylpyrocarbonate

1977 • 813 citations

[17] The kinetics of reversible tight-binding inhibition

1979 • 679 citations

The Reaction of Phenylglyoxal with Arginine Residues in Proteins

1968 • 636 citations

Chemical Reagents for Protein Modification

2018 • 424 citations

Ethoxyformylation of proteins. Reaction of ethoxyformic anhydride with .alpha.-chymotrypsin, pepsin, and pancreatic ribonuclease at pH 4

1970 • 388 citations

Differential reactivity of the functional sulfhydryl groups of cysteine-32 and cysteine-35 present in the reduced form of thioredoxin from Escherichia coli.

1980 • 364 citations

The principles of human biochemical genetics

1972 • 347 citations

Functional arginyl residues as NADH binding sites of alcohol dehydrogenases

1974 • 222 citations

AFFINITY LABELING OF PURINE NUCLEOTIDE SITES IN PROTEINS

1983 • 216 citations

Properties and Conformation of the Histidine Residues at the Active Site of Ribonuclease

1963 • 201 citations

Essential arginyl residue at the nucleotide binding site of creatine kinase

1975 • 196 citations

Role of band 3 tyrosine phosphorylation in the regulation of erythrocyte glycolysis

1991 • 186 citations

Current problems in mechanistic studies of serine and cysteine proteinases

1982 • 165 citations

Covalent structure, disulfide bonding, and identification of reactive surface and active site residues of human prostatic acid phosphatase

1991 • 164 citations

Specific and Irreversible Inactivation of Pepsin by Substrate-like Epoxides

1971 • 149 citations

Purification and characterization of a low-molecular-weight acid phosphatase—A phosphotyrosyl-protein phosphatase from bovine heart

1990 • 128 citations

Pre-steady-state and steady-state kinetic analysis of the low molecular weight phosphotyrosyl protein phosphatase from bovine heart

1991 • 120 citations

Human liver acid phosphatases: Purification and properties of a low-molecular-weight isoenzyme

1982 • 107 citations

Amino Acid Sequence around the Epoxide-reactive Residues in Pepsin

1972 • 77 citations

[25] Application of affinity labeling for studying structure and function of enzymes

1982 • 72 citations

Subcellular distribution of low- and high-molecularweight acid phosphatases

1976 • 71 citations

Purification and physicochemical characterization of a human placental acid phosphatase possessing phosphotyrosyl protein phosphatase activity

1988 • 68 citations

The low-molecular-weight acid phosphatase from bovine liver: Isolation, amino acid composition, and chemical modification studies

1981 • 68 citations

The Carboxylate Ion in the Active Center of Pepsin

1972 • 67 citations

The complete amino acid sequence of the low molecular weight cytosolic acid phosphatase

1989 • 67 citations

Identification of the Active-site Arginine in Rat Neutral Endopeptidase 24.11 (Enkephalinase) as Arginine 102 and Analysis of a Glutamine 102 Mutant

1989 • 58 citations

The reaction of thiol compounds and chloroacetamide. 2. The reaction between chloroacetamide and cysteine peptides

1962 • 58 citations

Leaving group dependence and proton inventory studies of the phosphorylation of a cytoplasmic phosphotyrosyl protein phosphatase from bovine heart

1991 • 50 citations

Properties of the Single Sulfhydryl Group of Streptococcal Proteinase

1967 • 46 citations

Reaction of the Sulfhydryl Group of Papain with Chloroacetic Acid

1969 • 45 citations

Purification and properties of an acid phosphatase from bovine brain

1970 • 43 citations

Consequences of molecular recognition in the S1-S2 intersubsite region of papain for catalytic-site chemistry. Change in pH-dependence characteristics and generation of an inverse solvent kinetic isotope effect by introduction of a P1-P2 amide bond into a two-protonic-state reactivity probe

1988 • 37 citations

Human red cell acid phosphatase: purification and properties of the A, B and C isozymes

1990 • 37 citations

Reaction of Chloroacetamide with the Sulfhydryl Group of Papain

1969 • 34 citations

Human liver acid phosphatases: Cysteine residues of the low-molecular-weight enzyme

1982 • 33 citations

Proton magnetic resonance studies of the states of ionization of histidines in native and modified subtilisins

1985 • 32 citations

Chemical Conversion of Aspartic Acid 52, a Catalytic Residue in Hen Egg-White Lysozyme, to Homoserine

1974 • 27 citations

Spectroscopic characterization of thioredoxin covalently modified with monofunctional organoarsenical reagents

1987 • 26 citations

Deuterium Isotope Effects on Papain Acylation

1979 • 26 citations

Evidence of acid phosphatase in the cytoplasm as a distinct entity

1988 • 25 citations

Protein band 3 phosphotyrosyl phosphatase. purification and characterization

1987 • 24 citations

The reaction of epoxides with yeast glyceraldehyde-3-phosphate dehydrogenase

1976 • 19 citations

Solvent isotope effects on tautomerization equilibria of papain and model thiolamines

1980 • 19 citations

Solvent isotope effects on the rates of alkylation of thiolamine models of papain

1980 • 16 citations

Importance of SH groups in catalysis by bovine brain acid phosphatase

1976 • 15 citations

Modification of an essential arginine residue associated with the plasma membrane ATPase of red beet (Beta vulgaris L.) storage tissue

1989 • 13 citations

Evidence for an arginine residue at the coenzyme-binding site of Escherichia coli isocitrate dehydrogenase

1989 • 10 citations