Aetiopathogenesis of primary sclerosing cholangitis

Survival and Causes of Death in Cirrhotic and in Noncirrhotic Patients with Primary Hemochromatosis

1985 • 1,069 citations

Support of cultured hepatocytes by a laminin-rich gel. Evidence for a functionally significant subendothelial matrix in normal rat liver.

1987 • 547 citations

Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis

2000 • 463 citations

PHENOTHIAZINE DYSKINESIA AFTER LEUCOTOMY

1964 • 397 citations

European journal of gastroenterology and hepatology

1990 • 365 citations

Maintenance of Differentiated Phenotype of Cultured Rat Hepatic Lipocytes by Basement Membrane Matrix

1989 • 353 citations

Neutrophil Cytoplasmic Antibodies: A Link Between Primary Sclerosing Cholangitis and Ulcerative Colitis

1991 • 351 citations

Non-smoking: a feature of ulcerative colitis.

1982 • 331 citations

Reversibility of Hepatic Fibrosis in Autoimmune Hepatitis

1997 • 288 citations

Acquired immunodeficiency syndrome cholangiopathy: Spectrum of disease

1989 • 282 citations

Primary Sclerosing Cholangitis: A Long-Term Follow-up Study

1987 • 278 citations

Risk factors and clinical presentation of hepatobiliary carcinoma in patients with primary sclerosing cholangitis: A case-control study

1998 • 276 citations

Association of primary sclerosing cholangitis with HLA-B8.

1983 • 270 citations

Modeling the impact of interferon alfa treatment on liver fibrosis progression in chronic hepatitis C: A dynamic view

1999 • 257 citations

Is liver fibrosis reversible?

2000 • 256 citations

Fibrogenesis I. New insights into hepatic stellate cell activation: the simple becomes complex

2000 • 223 citations

HLA Antigens and Immunoregulatory T Cells in Ulcerative Colitis Associated with Hepatobiliary Disease

1982 • 207 citations

Increased frequency of autoimmune diseases in patients with primary sclerosing cholangitis

2000 • 184 citations

A shared and unique epitope(s) on human colon, skin, and biliary epithelium detected by a monoclonal antibody

1990 • 182 citations

“Atypical p-ANCA” in IBD and hepatobiliary disorders react with a 50-kilodalton nuclear envelope protein of neutrophils and myeloid cell lines

2000 • 177 citations

Development and Disease in Proteinase-Deficient Mice

1998 • 177 citations

HLA class II haplotypes in primary sclerosing cholangitis patients from five European populations

1999 • 173 citations

Association of Primary Sclerosing Cholangitis with HLA-DRw52a

1990 • 171 citations

Epidemiology of primary sclerosing cholangitis in Spain

1994 • 171 citations

Serum autoantibodies in patients with primary sclerosing cholangitis

2000 • 160 citations

Role of extracellular matrix in regulating fenestrations of sinusoidal endothelial cells isolated from normal rat liver

1992 • 159 citations

Floxuridine-induced sclerosing cholangitis: An ischemic cholangiopathy?

1989 • 153 citations

Elevated Circulating Immune Complexes in Primary Sclerosing Cholangitis

1983 • 142 citations

Amino Acid Substitutions At Position 38 of the Drβ Polypeptide Confer Susceptibility to and Protection From Primary Sclerosing Cholangitis

1992 • 140 citations

HLA DR4 is a marker for rapid disease progression in primary sclerosing cholangitis

1994 • 135 citations

Ulcerative colitis and persistent liver dysfunction.

1983 • 135 citations

Serum autoantibodies, ulcerative colitis and primary sclerosing cholangitis.

1986 • 134 citations

Bile duct bacterial isolates in primary sclerosing cholangitis: a study of explanted livers

1998 • 134 citations

Primary sclerosing cholangitis is associated with nonsmoking: A case- control study

1996 • 132 citations

The Liver in Ulcerative Colitis

1971 • 124 citations

Primary sclerosing cholangitis: clinical presentation, natural history and prognostic variables: an Italian multicentre study. The Italian PSC Study Group.

1996 • 120 citations

Regression of hepatic fibrosis in hepatitis C with long-term interferon treatment.

1998 • 117 citations

Intercellular adhesion molecule-1 and MHC antigens on human intrahepatic bile duct cells: effect of pro-inflammatory cytokines.

1993 • 116 citations

HLA-DR and HLA-DQ are not markers for rapid disease progression in primary sclerosing cholangitis

1995 • 110 citations

Association of tumor necrosis factor polymorphism with primary sclerosing cholangitis

1999 • 104 citations

Association of the tumour necrosis factor α −308 but not the interleukin 10 −627 promoter polymorphism with genetic susceptibility to primary sclerosing cholangitis

2001 • 103 citations

A Functional Polymorphism of the Stromelysin Gene (MMP-3) Influences Susceptibility to Primary Sclerosing Cholangitis

2001 • 97 citations

Autoantibodies in sclerosing cholangitis against a shared peptide in biliary and colon epithelium

1994 • 95 citations

THE LIVER IN ULCERATIVE COLITIS THE SIGNIFICANCE OF RAISED SERUM-ALKALINE-PHOSPHATASE LEVELS

1959 • 90 citations

Hepatobiliary Complications of Inflammatory Bowel Disease

1988 • 89 citations

Prevalence of anti-neutrophil antibody in primary sclerosing cholangitis and ulcerative colitis using an alkaline phosphatase technique.

1992 • 85 citations

Importance of antineutrophil cytoplasmic antibodies in primary sclerosing cholangitis and ulcerative colitis: prevalence, titre, and IgG subclass.

1996 • 85 citations

Immunogenicity of biliary epithelium: Investigation of antigen presentation to CD4+ T cells

1996 • 80 citations

Transcriptional regulation of the albumin gene in cultured rat hepatocytes. Role of basement-membrane matrix.

1990 • 70 citations

Activation of the complement system in primary sclerosing cholangitis

1989 • 63 citations

A Study of Liver Disorder in Ulcerative Colitis

1961 • 58 citations

Expression of co-stimulatory factor B7-2 on the intrahepatic bile ducts in primary biliary cirrhosis and primary sclerosing cholangitis: an immunohistochemical study

1998 • 57 citations

Antineutrophil cytoplasmic antibodies in primary sclerosing cholangitis: defined specificities may be associated with distinct clinical features

1998 • 56 citations

Enterocytozoon bieneusi infection in acquired immunodeficiency syndrome-related sclerosing cholangitis

1992 • 55 citations

Molecular Biology and Medicine

1996 • 54 citations

Etiology and Pathogenesis in Primary Sclerosing Cholangitis

1994 • 52 citations

A 2-year follow-up study of anti-neutrophil antibody in primary sclerosing cholangitis: relationship to clinical activity, liver biochemistry and ursodeoxycholic acid treatment

1994 • 51 citations

Preferential Vβ3 usage by hepatic T lymphocytes in patients with primary sclerosing cholangitis

1997 • 46 citations

Comparison of Different Monoclonal Antibodies for the Immunohistochemical Assessment of Cell Proliferation in Routine Colorectal Biopsy Specimens

1994 • 46 citations

Lack of Concomitant Expression of ICAM-1 and HLA-DR on Bile Duct Cells from Patients with Primary Sclerosing Cholangitis and Primary Biliary Cirrhosis

1993 • 37 citations

Analysis of human common bile duct-associated T cells: evidence for oligoclonality, T cell clonal persistence, and epithelial cell recognition.

1997 • 37 citations

Pathogenesis of Sclerosing Cholangitis: The Role of Nonimmune Factors

1991 • 33 citations

the interleukin-1 and interleukin-10 gene polymorphisms in primary sclerosing cholangitis: no associations with disease susceptibility/resistance

2000 • 32 citations

Recent status of primary sclerosing cholangitis in Japan

1999 • 21 citations

Prevalence and Clinical Significance of Anti-Lactoferrin Autoantibodies in Inflammatory Bowel Diseases and Primary Sclerosing Cholangitis

1998 • 19 citations

Inhibition of T cell activation by normal human biliary epithelial cells

1999 • 19 citations

Administration of interleukin-2 induces major histocompatibility complex class II expression on the biliary epithelial cells, possibly through endogenous interferon-γ production

1992 • 16 citations

Inappropriate expression of blood group antigens on biliary and colonic epithelia in primary sclerosing cholangitis.

1993 • 11 citations

Familial occurrence of liver disease and inflammatory bowel disease in primary sclerosing cholangitis

1987 • 3 citations