4-Hydroxynonenal and transforming growth factor-β1 expression in colon cancer

TGF-β SIGNAL TRANSDUCTION

1998 • 7,582 citations

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription

1998 • 789 citations

Pathogenesis of liver fibrosis: role of oxidative stress

2000 • 630 citations

Activation of Stress Signaling Pathways by the End Product of Lipid Peroxidation

1999 • 578 citations

Role of Transforming Growth Factor-beta Signaling in Cancer

2000 • 525 citations

Oxidative damage and fibrogenesis

1997 • 483 citations

HNE interacts directly with JNK isoforms in human hepatic stellate cells.

1998 • 301 citations

The lipid peroxidation end product 4‐hydroxy‐2,3‐nonenal up‐regulates transforming growth factor β1 expression in the macrophage lineage: a link between oxidative injury and fibrosclerosis ¹

1997 • 264 citations

Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: a tissue microarray study.

2002 • 219 citations

Lipid peroxidation and cancer

1993 • 195 citations

Smad3/AP-1 interactions control transcriptional responses to TGF-β in a promoter-specific manner

2001 • 180 citations

Mechanisms and effects of lipid peroxidation

1993 • 169 citations

Selective Activation of the c-Jun N-Terminal Protein Kinase Pathway during 4-Hydroxynonenal-Induced Apoptosis of PC12 Cells

2000 • 117 citations

Down-regulation of TGF-β receptors in human colorectal cancer: implications for cancer development

1999 • 75 citations

Modulation by α- and γ-tocopherol and oxidized low-density lipoprotein of apoptotic signaling in human coronary smooth muscle cells∗

2000 • 67 citations

Reduced transforming growth factor-beta type II receptor (TGF-beta RII) expression in adenocarcinoma of the lung.

1999 • 63 citations

Transforming growth factor beta receptor 1 polyalanine polymorphism and exon 5 mutation analysis in breast and ovarian cancer.

2002 • 58 citations

Predictive value of expression of transforming growth factor-?1 and its receptors in transitional cell carcinoma of the urinary bladder

2001 • 58 citations

Vascular smooth muscle cell activation and growth by 4-hydroxynonenal

2001 • 47 citations

Oxidative Damage and Transforming Growth Factor β1 Expression in Pretumoral and Tumoral Lesions of Human Intestine

1997 • 46 citations

Abnormal nucleotide repeat sequence in the TGF‐βRII gene in hepatocellular carcinoma and in uninvolved liver tissue

2001 • 13 citations