Presence and function of chondroitin-4-sulfate on recombinant human soluble thrombomodulin

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

PEROXIDASE-LABELED ANTIBODY A NEW METHOD OF CONJUGATION

1974 • 2,413 citations

Enzymatic Methods for the Determination of Small Quantities of Isomeric Chondroitin Sulfates

1968 • 1,377 citations

Purification and Properties of Bacterial Chondroitinases and Chondrosulfatases

1968 • 1,238 citations

The Roles of Protein C and Thrombomodulin in the Regulation of Blood Coagulation

1989 • 1,059 citations

Preparation and properties of bovine factor VIII (antihemophilic factor)

1980 • 504 citations

Anticoagulant properties of bovine plasma protein C following activation by thrombin

1977 • 495 citations

Complex formation between thrombin and thrombomodulin inhibits both thrombin-catalyzed fibrin formation and factor V activation.

1982 • 434 citations

Mechanism of action of human activated protein C, a thrombin-dependent anticoagulant enzyme

1982 • 385 citations

Structure and function of thrombomodulin: a natural anticoagulant

1990 • 385 citations

Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation.

1987 • 358 citations

Structure and function of thrombomodulin: a natural anticoagulant

1990 • 318 citations

Mechanism of action of human activated protein C, a thrombin-dependent anticoagulant enzyme

1982 • 308 citations

Human thrombomodulin: complete cDNA sequence and chromosome localization of the gene

1987 • 209 citations

Isolation and characterization of thrombomodulin from human placenta.

1984 • 197 citations

Effect of thrombomodulin on the kinetics of the interaction of thrombin with substrates and inhibitors

1986 • 154 citations

The Last Three Consecutive Epidermal Growth Factor-like Structures of Human Thrombomodulin Comprise the Minimum Functional Domain for Protein C-activating Cofactor Activity and Anticoagulant Activity

1989 • 149 citations

A 10-kDa cyanogen bromide fragment from the epidermal growth factor homology domain of rabbit thrombomodulin contains the primary thrombin binding site.

1988 • 130 citations

A domain Composed of Epidermal Growth Factor-like Structures of Human Thrombomodulin Is Essential for Thrombin Binding and for Protein C Activation

1989 • 109 citations

Proteolytic formation and properties of functional domains of thrombomodulin.

1987 • 98 citations

Microthrombomodulin

1989 • 86 citations

Relationship between anticoagulant activities and polyanionic properties of rabbit thrombomodulin.

1988 • 81 citations

Binding of thrombin to thrombomodulin accelerates inhibition of the enzyme by antithrombin III. Evidence for a heparin-independent mechanism

1987 • 70 citations

Domain structure of the endothelial cell receptor thrombomodulin as deduced from modulation of its anticoagulant functions. Evidence for a glycosaminoglycan-dependent secondary binding site for thrombin.

1990 • 53 citations

Effect of rabbit thrombomodulin on thrombin inhibition by antithrombin in the presence of heparin

1989 • 25 citations

Decreased thrombin affinity of cell-surface thrombomodulin following treatment of cultured endothelial cells with β-D-xyloside

1990 • 23 citations