Physiological amounts of ascorbate potentiate phorbol ester-induced nuclear-binding of AP-1 transcription factor in cells of macrophagic lineage

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

1991 • 3,396 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

AP-1 function and regulation

1997 • 2,833 citations

The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases

1995 • 2,441 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor.

1993 • 1,330 citations

Flow Cytometric Analysis of Respiratory Burst Activity in Phagocytes With Hydroethidine and 2′,7′-Dichlorofluorescin

1990 • 869 citations

Continuous c-fos expression precedes programmed cell death in vivo

1993 • 784 citations

A Drosophila RNA polymerase II transcription factor contains a promoter-region-specific DNA-binding activity

1984 • 537 citations

Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling

1996 • 503 citations

Action of ascorbic acid as a scavenger of active and stable oxygen radicals

1991 • 484 citations

Ascorbic acid recycling in human neutrophils

1993 • 290 citations

Calcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytes

1998 • 270 citations

Thiol-Reactive Metal Compounds Inhibit NF-κB Activation by Blocking IκB Kinase

2000 • 219 citations

A requirement for extracellular signal-regulated kinase (ERK) function in the activation of AP-1 by Ha-Ras, phorbol 12-myristate 13-acetate, and serum.

1994 • 214 citations

Redox Signals and NF-κB Activation in T Cells

1998 • 206 citations

Signal transduction for nuclear factor-kappa B activation. Proposed location of antioxidant-inhibitable step.

1994 • 158 citations

Protein kinase C isoenzymes: regulation and function.

1996 • 132 citations

Oxidative Stress, Cell Activation and Viral Infection

1994 • 91 citations

Role of ascorbate in the activation of NF-κB by tumour necrosis factor-α in T-cells

1997 • 47 citations

Differentiation modulates the balance of positive and negative Jun/AP-1 DNA binding activities to regulate cellular proliferative potential: different effects in nontransformed and transformed cells.

1996 • 37 citations

Two distinct uptake mechanisms for ascorbate and dehydroascorbate in human lymphoblasts and their interaction with glucose

1997 • 36 citations

Redox Control of Gene Expression by Eukaryotic Transcription Factors NF-κB, AP-1 and SRF/TCF

1994 • 33 citations

PROTEIN KINASE C ISOENZYMES

2010 • 8 citations