Distribution and Roles of Purinoceptor Subtypes

Psychopharmacology: The third generation of progress

1988 • 3,403 citations

Extracellular ATP: effects, sources and fate

1986 • 1,666 citations

The physiological activity of adenine compounds with especial reference to their action upon the mammalian heart1

1929 • 1,470 citations

ADENOSINE REGULATES VIA TWO DIFFERENT TYPES OF RECEPTORS, THE ACCUMULATION OF CYCLIC AMP IN CULTURED BRAIN CELLS

1979 • 1,370 citations

Is there a basis for distinguishing two types of P2-purinoceptor?

1985 • 1,353 citations

Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin

1986 • 1,264 citations

Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor

1986 • 917 citations

Cell membrane receptors for drugs and hormones: A multidisciplinary approach

1979 • 850 citations

A novel receptor-operated Ca2+-permeable channel activated by ATP in smooth muscle

1987 • 786 citations

The role of adenosine and its nucleotides in central synaptic transmission

1981 • 767 citations

A basis for distinguishing two types of purinergic receptor

1978 • 725 citations

Adenosine receptors: targets for future drugs

1982 • 681 citations

Do some nerve cells release more than one transmitter?

1976 • 633 citations

Suramin: a reversible P₂‐purinoceptor antagonist in the mouse vas deferens

1988 • 426 citations

Role of the intima in cholinergic and purinergic relaxation of isolated canine femoral arteries.

1981 • 380 citations

The use of the slowly degradable analog, α,β-methylene ATP, to produce desensitisation of the P2-purinoceptor: Effect on non-adrenergic, non-cholinergic responses of the guinea-pig urinary bladder

1982 • 337 citations

Suramin antagonizes responses to P₂‐purinoceptor agonists and purinergic nerve stimulation in the guinea‐pig urinary bladder and taenia coli

1990 • 317 citations

Adenosine receptors and calcium: Basis for proposing a third (A3) adenosine receptor

1986 • 284 citations

The changing face of autonomic neurotransmission*

1986 • 272 citations

Extracellular ATP4- promotes cation fluxes in the J774 mouse macrophage cell line.

1987 • 201 citations

Vasodilatation: Vascular Smooth Muscle, Peptides, Autonomic Nerves, and Endothelium

1989 • 191 citations

Cationic channels activated by extracellular atp in rat sensory neurons

1988 • 174 citations

Is ATP a central synaptic mediator for certain primary afferent fibers from mammalian skin?

1984 • 165 citations

P2 purinoceptors on vascular endotheliai cells: physiological significance and transduction mechanisms

1990 • 160 citations

ATP‐Evoked Ca²⁺ Mobilisation and Prostanoid Release from Astrocytes: P₂‐Purinergic Receptors Linked to Phosphoinositide Hydrolysis

1989 • 156 citations

ATP‐activated channels gate calcium entry in single smooth muscle cells dissociated from rabbit ear artery.

1989 • 153 citations

An ATP‐sensitive conductance in single smooth muscle cells from the rat vas deferens.

1988 • 152 citations

Characteristics of the P2 purinoceptor that mediates prostacyclin production by pig aortic endothelial cells

1987 • 145 citations

Transmitter-like action of ATP on patched membranes of cultured myoblasts and myotubes

1983 • 142 citations

Adenosine and Adenosine Receptors

1990 • 142 citations

Role of adenine compounds in autonomic neurotransmission

1988 • 137 citations

Effects of adenosine 5′-monophosphate and adenosine 5′-triphosphate on functionally identified units in the cat spinal dorsal horn. Evidence for a differential effect of adenosine 5′-triphosphate on nociceptive vs non-nociceptive units

1985 • 128 citations

Extracellular ATP activates polyphosphoinositide breakdown and Ca2+ mobilization in Ehrlich ascites tumor cells

1986 • 125 citations

Different P2-purinergic receptor subtypes of endothelium and smooth muscle in canine blood vessels.

1987 • 117 citations

ATP and other adenine compounds increase mechanical activity and inositol trisphosphate production in rat heart.

1988 • 114 citations

External ATP triggers a biphasic activation process of a calcium-dependent K+ channel in cultured bovine aortic endothelial cells

1988 • 105 citations

Vasodilatation : vascular smooth muscle, peptides, autonomic nerves, and endothelium

1988 • 104 citations

Characterisation of the ATP4− receptor that mediates permeabilisation or rat mast cells

1988 • 101 citations

Guanine Nucleotide-sensitive Interaction of a Radiolabeled Agonist with a Phospholipase C-linked P2y-purinergic Receptor

1989 • 98 citations

Extracellular nucleotides stimulate receptor-mediated calcium mobilization and inositol phosphate production in human fibroblasts

1989 • 95 citations

An Introduction to Purinergic Receptors

1981 • 94 citations

Excitatory action of ATP on embryonic chick muscle

1986 • 91 citations

Purinergic receptors in the heart.

1980 • 85 citations

Stimulation of glycogenolysis by adenine nucleotides in the perfused rat liver

1986 • 85 citations

Effects of extracellular ATP on ion transport systems and [Ca2+]i in rat parotid acinar cells. Comparison with the muscarinic agonist carbachol.

1990 • 84 citations

Characterization of the liver P2-purinoceptor involved in the activation of glycogen phosphorylase

1986 • 84 citations

The Classification of Receptors for Adenosine and Adenine Nucleotides

1985 • 83 citations

Interaction of ATP and Calcium on the Rat Mast Cell: Effect on Histamine Release

1974 • 81 citations

Extracellular ATP has a potent effect to enhance cystolic calcium and contractility in single ventricular myocytes

1988 • 80 citations

ATP stimulates calcium influx in primary astrocyte cultures

1988 • 78 citations

P_2Y‐purinoceptor regulation of surfactant secretion from rat isolated alveolar type II cells is associated with mobilization of intracellular calcium

1987 • 75 citations

Adenosine triphosphate-activated inward current in isolated smooth muscle cells from rat vas deferens

1987 • 75 citations

Blood Platelet Receptors for ADP and for Adenosine

1981 • 74 citations

Stimulation of P1-purinoceptors by ATP depends partly on its conversion to AMP and adenosine and partly on direct action

1984 • 72 citations

The actions of adenosine 5′‐triphosphate on guinea‐pig intracardiac neurones in culture

1990 • 63 citations

An electrophysiological analysis of the effect of reactive blue 2, a putative P2-purinoceptor antagonist, on inhibitory junction potential of rat caecum

1986 • 60 citations

Adenosine Receptors and Adenylate Cyclase Interactions

1983 • 57 citations

P2‐purinoceptor‐stimulated phosphoinositide turnover in chick myotubes calcium mobilization and the role of guanyl nucleotide‐binding proteins

1988 • 56 citations

Indications for P2-purinoceptor subtypes in guinea pig smooth muscle

1988 • 54 citations

Hepatocyte heterogeneity in response to extracellular ATP

1987 • 52 citations

Phosphatidylinositol 4,5-bisphosphate hydrolysis in turkey erythrocytes is regulated by P2y purinoceptors.

1989 • 52 citations

Pharmacological effects of isopolar phosphonate analogues of ATP on P₂‐purinoceptors in guinea‐pig taenia coli and urinary bladder

1987 • 49 citations

Identification of P_2Y purinoceptors associated with voltage‐activated cation channels in cardiac ventricular myocytes of the rat

1989 • 41 citations

[3H]-α,β-Methylene ATP, a radioligand labelling P2-purinoceptors

1989 • 41 citations

Adenosine 5′-(2-fluorodiphosphate) is a selective agonist at P2-purinoceptors mediating relaxation of smooth muscle

1988 • 38 citations

Extracellular adenosine triphosphate activates phospholipase C and mobilizes intracellular calcium in primary cultures of sheep anterior pituitary cells

1989 • 38 citations

The effects of purine nucleotides on transmission in vesical parasympathetic ganglia of the cat

1989 • 37 citations

Lymphocyte Membrane Adenosine Receptors Coupled to Adenylate Cyclase Properties and Occurrence in Various Lymphocyte Subclasses

1981 • 35 citations

Functional evidence for involvement of P2 purinoceptors in the ATP stimulation of phosphatidylcholine secretion in type II alveolar epithelial cells

1988 • 32 citations

Antagonistic properties of four suramin-related compounds at vascular purine P2X receptors in the pithed rat

1990 • 21 citations

Purine receptors: classification and properties

1984 • 21 citations

Exogenous ATP causes the contraction of intact fibroblasts in vitro

1988 • 14 citations

Cardiovascular receptors. Molecular, pharmacological, and therapeutic aspects

1980 • 13 citations

Structure Activity Relationships for Adenine Nucleotide Receptors on Mast Cells, Human Platelets, and Smooth Muscle

1990 • 13 citations

Deleted Work

1955 • 0 citations