The Classification of Receptors for Adenosine and Adenine Nucleotides

A STUDY OF THE ADRENOTROPIC RECEPTORS

1948 • 2,856 citations

Handbook of Psychopharmacology

1988 • 2,778 citations

Differentiation of Receptor Systems activated by Sympathomimetic Amines

1967 • 2,054 citations

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

1980 • 1,750 citations

The physiological activity of adenine compounds with especial reference to their action upon the mammalian heart1

1929 • 1,470 citations

ADENOSINE REGULATES VIA TWO DIFFERENT TYPES OF RECEPTORS, THE ACCUMULATION OF CYCLIC AMP IN CULTURED BRAIN CELLS

1979 • 1,370 citations

Pirenzepine distinguishes between different subclasses of muscarinic receptors

1980 • 1,299 citations

Subclasses of external adenosine receptors.

1980 • 1,087 citations

The role of calcium in the release of neurotransmitter substances and hormones.

1970 • 871 citations

The role of adenosine and its nucleotides in central synaptic transmission

1981 • 767 citations

A basis for distinguishing two types of purinergic receptor

1978 • 725 citations

Adenosine receptors and behavioral actions of methylxanthines.

1981 • 705 citations

Adenosine receptors in brain membranes: binding of N6-cyclohexyl[3H]adenosine and 1,3-diethyl-8-[3H]phenylxanthine.

1980 • 554 citations

Adenosine receptors in the central nervous system: Relationship to the central actions of methylxanthines

1981 • 535 citations

Autoradiographic localization of adenosine receptors in rat brain using [3H]cyclohexyladenosine

1982 • 417 citations

The use of the slowly degradable analog, α,β-methylene ATP, to produce desensitisation of the P2-purinoceptor: Effect on non-adrenergic, non-cholinergic responses of the guinea-pig urinary bladder

1982 • 337 citations

Physiology and pharmacology of adenosine derivatives

1984 • 311 citations

Inhibition of excitatory junction potentials in guinea-pig vas deferens by α, β-methylene-ATP: Further evidence for ATP and noradrenaline as cotransmitters

1984 • 301 citations

Characterization of adenosine receptors in rat brain by (?)[3H]N6-phenylisopropyladenosine

1980 • 296 citations

Evidence that ATP acts as a co-transmitter with noradrenaline in sympathetic nerves supplying the guinea-pig vas deferens

1983 • 277 citations

Xanthine derivatives as adenosine receptor antagonists

1982 • 239 citations

Adenosine receptor activation in human fibroblasts: nucleoside agonists and antagonists

1980 • 198 citations

Preparation and Properties of 5'-Nucleotidase from Smooth Muscle of Small Intestine

1970 • 187 citations

Biological Actions of the Adenine Nucleotides

1950 • 184 citations

Adenosine receptor binding: structure-activity analysis generates extremely potent xanthine antagonists.

1983 • 164 citations

Inhibition of slow action potentials of guinea pig atrial muscle by adenosine: A possible effect on Ca2+ influx

1975 • 157 citations

Biochemical characterization of putative central purinergic receptors by using 2-chloro[3H]adenosine, a stable analog of adenosine.

1980 • 155 citations

Adenosine Receptor Agonists Inhibit K⁺‐Evoked Ca²⁺ Uptake by Rat Brain Cortical Synaptosomes

1982 • 142 citations

Sister Chromatid Exchanges in Human Lymphocytes After Exposure to Diagnostic Ultrasound

1979 • 141 citations

Adenosine receptor-mediated inhibition of rat cerebral cortical adenylate cyclase by a GTP-dependent process.

1980 • 141 citations

An A1-adenosine receptor, characterized by [3H]cyclohexyladenosine binding, mediates the depression of evoked potentials in a rat hippocampal slice preparation

1982 • 140 citations

8-Phenyltheophylline: A potent P1-purinoceptor antagonist

1981 • 138 citations

Adenosine Receptors Mediating Cyclic AMP Productioin the Rat Hippocampus

1982 • 137 citations

Adenosine relaxes the aorta by interacting with an A2 receptor and an intracellular site

1983 • 132 citations

Effect of apamin on the electrical responses of smooth muscle to adenosine 5′-triphosphate and to non-adrenergic, non-cholinergic nerve stimulation

1980 • 130 citations

Regulatory functions of adenosine.

1987 • 129 citations

Outlines of receptor theory

1980 • 129 citations

Evidence for an Ax‐adenosine receptor in the guinea‐pig atrium

1983 • 128 citations

Purinergic Receptors: Photoaffinity Analog of Adenosine Triphosphate Is a Specific Adenosine Triphosphate Antagonist

1980 • 124 citations

A common basis for inhibition of nucleoside transport by dipyridamole and nitrobenzylthioinosine?

1980 • 123 citations

Chemical Pharmacology of the Synapse

1977 • 121 citations

Adenosine receptors in fat cells. Identification by (-)-N6-[3H]phenylisopropyladenosine binding.

1981 • 118 citations

Adenosine receptors mediating cardiac depression

1982 • 115 citations

Ligand selectivity of dog coronary adenosine receptor resembles that of adenylate cyclase stimulatory (Ra) receptors.

1983 • 110 citations

The dextro and levorotatory isomers of N-phenylisopropyladenosine: Stereospecific effects on cyclic AMP-formation and evoked synaptic responses in brain slices

1979 • 106 citations

Stereospecificity in some central and circulatory effects of phenylisopropyl-adenosine (PIA).

1975 • 99 citations

EVIDENCE FOR AN A₂/R_a ADENOSINE RECEPTOR IN THE GUINEA‐PIG TRACHEA

1982 • 98 citations

An Introduction to Purinergic Receptors

1981 • 94 citations

The ionic basis of adenosine receptor actions on post‐ganglionic neurones in the rat.

1983 • 94 citations

Solubilized Adenosine Receptors in the Brain: Regulation of Guanine Nucleotides

1982 • 89 citations

Differential location of adenosine A1 and A2 receptors in striatum

1983 • 86 citations

STRUCTURE‐ACTIVITY RELATIONS FOR PRESYNAPTIC INHIBITION OF NORADRENERGIC AND CHOLINERGIC TRANSMISSION BY ADENOSINE: EVIDENCE FOR ACTION ON A₁ RECEPTORS

1981 • 86 citations

Chemical pharmacology of the synapse

1976 • 84 citations

Studies on the stereoselectivity of the P₂‐purinoceptor

1983 • 79 citations

Blood Platelet Receptors for ADP and for Adenosine

1981 • 74 citations

Stimulation of P1-purinoceptors by ATP depends partly on its conversion to AMP and adenosine and partly on direct action

1984 • 72 citations

Specific binding of 2-[³H]chloroadenosine to rat brain cortical membranes

1980 • 69 citations

EVIDENCE IN SUPPORT OF THE P₁/P₂ PURINOCEPTOR HYPOTHESIS IN THE GUINEA‐PIG TAENIA COLI

1981 • 68 citations

Effect of adenosine on calcium uptake by intact and cultured vascular smooth muscle

1982 • 67 citations

Can ATP stimulate P1-receptors in guinea-pig atrium without conversion to adenosine?

1982 • 62 citations

Characterization of [3H]adenosine binding to fat cell membranes.

1978 • 60 citations

Functional identification of adenylate cyclase-coupled adenosine receptors in rat brain microvessels

1982 • 57 citations

Specific binding of 3H-adenosine to rat brain membranes

1979 • 57 citations

Adenosine in the Regulation of Neurotransmitter Release in the Peripheral Nervous System

1983 • 56 citations

Adenosine receptors in rat testes: Labeling with 3Hcyclohexyladenosine

1981 • 52 citations

Inhibition of brain adenosine deaminase by 2′‐deoxycoformy cin and erythro‐9‐(2‐hydroxy‐3‐nonyl) adenine

1978 • 52 citations

Inhibition of adenosine uptake in human erythrocytes by adenosine-5'-carboxamides, xylosyladenine, dipyridamole, hexobendine, and p-nitrobenzylthioguanosine

1978 • 52 citations

Adenosine receptor agonists: Binding and adenylate cyclase stimulation in rat liver plasma membranes

1982 • 50 citations

RELAXATION OF ISOLATED TAENIA COLI OF GUINEA‐PIG BY ENANTIOMERS OF 2‐AZIDO ANALOGUES OF ADENOSINE AND ADENINE NUCLEOTIDES

1979 • 48 citations

Parallel investigations of the effects of adenosine on evoked potentials and cyclic AMP accumulation in hippocampus slices of the rat

1979 • 47 citations

Evidence that the P₁‐purinoceptor in the guinea‐pig taenia coli is an A₂‐subtype

1984 • 42 citations

Effects of d- and l- enantiomers of adenosine, AMP and ADP and their 2-chloro- and 2-azido- analogues on human platelets

1979 • 40 citations

EVIDENCE FOR STEREOSPECIFICITY OF THE P₁‐PURINOCEPTOR

1982 • 39 citations

Comparison of the activity of 2′-deoxycoformycin and erythro-9-(2-hydroxy-3-nonyl)adenine in vivo

1979 • 39 citations

The binding of [3H]adenosine to synaptosomal and other preparations from the mammalian brain

1981 • 39 citations

Saturable binding of adenosine to the dog heart microsomal fraction: competitive inhibition by aminophylline.

1979 • 34 citations

Evidence for an inhibitory prejunctional P1-purinoceptor in the rat portal vein with characteristics of the A2 rather than of the A1 subtype

1984 • 32 citations

Purine receptors in the rat anococcygeus muscle.

1983 • 31 citations

agonist selectivity of mono- and dihydroxy-2-N,N-DI-n-propylaminotetralins

1984 • 30 citations

Purinergic Receptors in Blood Vessels

1981 • 29 citations

Effect of arylazido aminopropionyl ATP (ANAPP3), a putative ATP antagonist, on ATP responses of isolated guinea pig smooth muscle

1982 • 29 citations

Adenosine receptors in rat brain membranes: Characterization of high affinity binding of [3H]-2-chloroadenosine

1982 • 28 citations

Bromocriptine and lisuride stimulate the accumulation of cyclic AMP in intact slices but not in homogenates of rat neostriatum

1979 • 26 citations

Binding of adenosine to the crude plasma membrane fraction isolated from dog coronary and carotid arteries.

1980 • 23 citations

General Aspects of Binding of Ligands to Adenosine Receptors

1983 • 21 citations

Autoradiographic demonstration of peripheral adenosine binding sites using [3H]NECA

1983 • 13 citations

Demonstration of a Putative Adenosine Receptor in Rabbit Aorta

1982 • 13 citations

The emergence of modern man

1980 • 13 citations

Characterization of [<sup>3</sup>H]-Adenosine Binding to Media Membranes of Hog Carotid Arteries

1982 • 13 citations

Characteristics of high-affinity [3H]adenosine binding to rat brain synaptosomes and turkey erythrocyte membranes

1982 • 13 citations

Antagonism of presynaptic adenosine receptors by theophylline 9-β-<scp>D</scp>-riboside and 8-phenyltheophylline

1981 • 12 citations

Action of phenylisopropyl-adenosine (PIA) on the synthesis of corticosterone in rats.

1977 • 3 citations