Cell shape, cytoskeletal mechanics, and cell cycle control in angiogenesis

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Angiogenesis in cancer, vascular, rheumatoid and other disease

1995 • 7,717 citations

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Mechanotransduction Across the Cell Surface and Through the Cytoskeleton

1993 • 2,947 citations

Role of cell shape in growth control

1978 • 2,434 citations

G ₁ Events and Regulation of Cell Proliferation

1989 • 2,203 citations

Focal Adhesions: Transmembrane Junctions Between the Extracellular Matrix and the Cytoskeleton

1988 • 2,137 citations

Signal transduction from the extracellular matrix.

1993 • 1,727 citations

Engineering Cell Shape and Function

1994 • 1,447 citations

Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton

1993 • 1,124 citations

Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix.

1989 • 877 citations

Structural interaction of cytoskeletal components

1981 • 766 citations

Integrins as mechanochemical transducers

1991 • 684 citations

Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells.

1987 • 591 citations

Action of cytochalasin D on cytoskeletal networks.

1982 • 581 citations

Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three-dimensional organization and protein composition.

1984 • 545 citations

Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes.

1988 • 534 citations

Control of cytoskeletal mechanics by extracellular matrix, cell shape, and mechanical tension

1994 • 528 citations

Mapping replicational sites in the eucaryotic cell nucleus.

1989 • 520 citations

Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex.

1995 • 503 citations

Fibronectin controls capillary endothelial cell growth by modulating cell shape.

1990 • 498 citations

Nuclear Protein Matrix: Association with Newly Synthesized DNA

1975 • 487 citations

An ordered sequence of events is required before BALB/c-3T3 cells become committed to DNA synthesis

1978 • 472 citations

How does extracellular matrix control capillary morphogenesis?

1989 • 466 citations

Switching from differentiation to growth in hepatocytes: Control by extracellular matrix

1992 • 463 citations

From signal to pseudopod

1989 • 460 citations

Isometric contraction by fibroblasts and endothelial cells in tissue culture: a quantitative study

1992 • 456 citations

Cellular Tensegrity: Exploring How Mechanical Changes in the Cytoskeleton Regulate Cell Growth, Migration, and Tissue Pattern during Morphogenesis

1994 • 428 citations

Protein synthesis requires cell-surface contact while nuclear events respond to cell shape in anchorage-dependent fibroblasts

1980 • 399 citations

A Link Between Cyclin A Expression and Adhesion-Dependent Cell Cycle Progression

1993 • 399 citations

Unpolymerized tubulin modulates the level of tubulin mRNAs

1981 • 392 citations

Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape.

1991 • 368 citations

Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown.

1993 • 335 citations

Quantitative studies of endothelial cell adhesion. Directional remodeling of focal adhesion sites in response to flow forces.

1994 • 322 citations

Fibroblast contractility and actin organization are stimulated by microtubule inhibitors

1989 • 303 citations

Tension and compression in the cytoskeleton of PC-12 neurites. II: Quantitative measurements.

1988 • 288 citations

Altering the cellular mechanical force balance results in integrated changes in cell, cytoskeletal and nuclear shape

1992 • 274 citations

Synthesis of labile, serum-dependent protein in early G ₁ controls animal cell growth

1979 • 273 citations

Control of intracellular pH and growth by fibronectin in capillary endothelial cells.

1990 • 241 citations

Inhibition of angiogenesis through modulation of collagen metabolism.

1988 • 240 citations

Cytoskeletal filament assembly and the control of cell spreading and function by extracellular matrix

1995 • 234 citations

Endothelial growth factors and extracellular matrix regulate DNA synthesis through modulation of cell and nuclear expansion

1987 • 225 citations

Tension and compression in the cytoskeleton of PC 12 neurites.

1985 • 224 citations

Reorganization of basement membrane matrices by cellular traction promotes the formation of cellular networks in vitro.

1992 • 221 citations

Transmembrane signalling by integrins

1992 • 219 citations

The riddle of morphogenesis: A question of solution chemistry or molecular cell engineering?

1993 • 219 citations

Stress relaxation of contracted collagen gels: Disruption of actin filament bundles, release of cell surface fibronectin, and down-regulation of DNA and protein synthesis

1991 • 217 citations

A Possible Mechanism for Inhibition of Angiogenesis by Angiostatic Steroids: Induction of Capillary Basement Membrane Dissolution*

1986 • 214 citations

The permeability of the nuclear envelope in dividing and nondividing cell cultures.

1990 • 210 citations

Role of basal lamina in neoplastic disorganization of tissue architecture.

1981 • 202 citations

Simple and Complex Cell Cycles

1989 • 192 citations

Integrating with integrins.

1994 • 189 citations

Integrin binding and cell spreading on extracellular matrix act at different points in the cell cycle to promote hepatocyte growth.

1994 • 187 citations

Cell adhesion induces expression of growth-associated genes in suspension-arrested fibroblasts.

1988 • 174 citations

Rapid Induction and Isolation of Focal Adhesion Complexes

1993 • 174 citations

Spreading of trypsinized cells: Cytoskeletal dynamics and energy requirements

1990 • 137 citations

Cell structure and DNA organization.

1991 • 133 citations

G1/S control of anchorage-independent growth in the fibroblast cell cycle.

1991 • 120 citations

Expression of the differentiated phenotype by epithelial cells in vitro is regulated by both biochemistry and mechanics of the substratum

1989 • 116 citations

Extracellular matrix as a solid-state regulator in angiogenesis: identification of new targets for anti-cancer therapy.

1992 • 113 citations

Regulation of Nuclear Transport in Proliferating and Quiescent Cells

1993 • 107 citations

Gene Expression During Normal and Malignant Differentiation

1985 • 101 citations

Tension as a regulator and integrator of axonal growth

1990 • 94 citations

Intermediate Filaments May Prevent Buckling of Compressively Loaded Microtubules

1990 • 80 citations

A thermodynamic model for force integration and microtubule assembly during axonal elongation

1988 • 80 citations

Integrin-dependent induction of early growth response genes in capillary endothelial cells

1996 • 66 citations

Role of Nuclear Size in Cell Growth Initiation

1979 • 64 citations

Effect of microtubule-destroying drugs on the spreading and shape of cultured epithelial cells

1985 • 59 citations

Extracellular matrix controls tubulin monomer levels in hepatocytes by regulating protein turnover.

1994 • 54 citations

Actin Cortex and Microtubular System in Morphogenesis: Cooperation and Competition

1987 • 52 citations

Chromatin motion in neuronal interphase nuclei: Changes induced by disruption of intermediate filaments

1991 • 49 citations

The shape of cultured epithelial cells does not depend on the integrity of their microtubules

1988 • 40 citations

Cell cycle perturbations in normal and transformed fibroblasts caused by detachment from the substratum

1983 • 36 citations

Fluorimetric measurements and chromatin condensation patterns of nuclei from 3T3 cells throughout G1

1981 • 35 citations

Critical nuclear DNA size and distribution associated with S phase initiation

1986 • 29 citations

Observations on the membranous components of amphibian oocyte nucleoli

1971 • 27 citations

Gene Expression during Normal and Malignant Differentiation

1986 • 21 citations

In vitro large-wound re-endothelialization. Inhibition of centrosome redistribution by transient inhibition of transcription after wounding prevents rapid repair.

1993 • 20 citations

Regulation of Nucleocytoplasmic Transport by Mechanical Forces Transmitted Through the Cytoskeleton

1992 • 16 citations

Autoradiographic investigations on cell shape-mediated growth regulation of lens epithelial cells in culture.

1989 • 3 citations