Characterization of cytokine production in murine Trypanosoma cruzi infection by in situ immunocytochemistry: Lack of association between susceptibility and type 2 cytokine production

Regulation of Immunity to Parasites by T Cells and T Cell-Derived Cytokines

1992 • 843 citations

The microbicidal activity of interferon‐γ‐treated macrophages against Trypanosoma cruzi involves an L‐arginine‐dependent, nitrogen oxide‐mediated mechanism inhibitable by interleukin‐10 and transforming growth factor‐β

1992 • 437 citations

Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection.

1994 • 365 citations

Interleukin 10 and interferon gamma regulation of experimental Trypanosoma cruzi infection.

1992 • 364 citations

Susceptibility of β2-microglobulin-deficient mice to Trypanosoma cruzi infection

1992 • 329 citations

Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor beta (TGF-beta).

1991 • 309 citations

In vivo administration of recombinant IFN-gamma induces macrophage activation, and prevents acute disease, immune suppression, and death in experimental Trypanosoma cruzi infections.

1988 • 256 citations

Endogenous IFN-gamma is required for resistance to acute Trypanosoma cruzi infection in mice.

1991 • 242 citations

Depletion of CD8+ T cells increases susceptibility and reverses vaccine-induced immunity in mice infected with Trypanosoma cruzi.

1990 • 238 citations

T-cell and cytokine responses in leishmaniasis

1993 • 221 citations

Recombinant granulocyte/macrophage colony-stimulating factor activates macrophages to inhibit Trypanosoma cruzi and release hydrogen peroxide. Comparison with interferon gamma.

1987 • 215 citations

IL-10 mediates susceptibility to Trypanosoma cruzi infection.

1994 • 199 citations

Trypanosoma cruzi: Role of the immune response in the natural resistance of inbred strains of mice

1978 • 153 citations

Modification of T-cell proliferation and interleukin 2 production in mice infected with Trypanosoma cruzi.

1983 • 125 citations

Virulence associated plasmids of Salmonella serotype typhimurium in experimental murine infection

1986 • 109 citations

Xid-associated resistance to experimental Chagas' disease is IFN-gamma dependent.

1993 • 98 citations

Kinetic analysis of antigen-specific immune responses in resistant and susceptible mice during infection with Trypanosoma cruzi.

1993 • 96 citations

Trypanosoma cruzi-induced suppression of IL-2 production. II. Evidence for a role for suppressor cells.

1988 • 92 citations

Predominance of CD8+ T Lymphocytes in the Inflammatory Lesions of Mice with Acute Trypanosoma cruzi Infection

1993 • 83 citations

Differential control of IFN-gamma and IL-2 production during Trypanosoma cruzi infection.

1991 • 78 citations

Tumour necrosis factor (cachectin) production during experimental Chagas' disease.

1988 • 76 citations

Restoration of in vitro immune responses of spleen cells from mice infected with Trypanosoma cruzi by supernatants containing interleukin 2.

1984 • 74 citations

Isolation from Trypanosoma cruzi-infected mice of CD8+, MHC-restricted cytotoxic T cells that lyse parasite-infected target cells.

1993 • 60 citations

Trypanosoma cruzi-induced suppression of IL-2 production. I. Evidence for the presence of IL-2-producing cells.

1988 • 54 citations

Immune resistance to Trypanosoma cruzi: Synergy of specific antibodies and recombinant interferon gamma in vivo

1987 • 50 citations

Effect of anti-γ-interferon and anti-interleukin-4 administration on the resistance of mice against infection with reticulotropic and myotropic strains of Trypanosoma cruzi

1993 • 48 citations

Susceptible mice present higher macrophage activation than resistant mice during infections with myotropic strains of Trypanosoma cruzi

1989 • 46 citations

A histopathological analysis of the course of myocarditis in C3H/He mice infected with Trypanosoma cruzi clone Sylvio-X10/4

1986 • 45 citations

Why vaccines do not work in chagas disease

1986 • 41 citations

Construction and use of a multi-competitor gene for quantitative RT-PCR using existing primer sets

1995 • 36 citations

Recombinant granulocyte-macrophage colony-stimulating factor restores deficient immune responses in mice with chronic Trypanosoma cruzi infections.

1990 • 31 citations

Trypanosoma cruzi infection suppresses nuclear factors that bind to specific sites on the interleukin

1994 • 22 citations

Molecular and immunological aspects of parasitism

1992 • 18 citations

Selective suppressive effects of Trypanosoma cruzi infection on IL-2, c-myc, and c-fos gene expression.

1992 • 18 citations

Medium-scale production and purification of monoclonal antibodies in protein-free medium.

1991 • 15 citations

The Effect of Interleukin‐2 on Parasitemia and Myocarditis in Experimental Chagas' Disease

1989 • 9 citations

Organ‐Specific Regulation of Interferon‐γ, Interleukin‐2 and Interleukin‐2 Receptor during Murine Infection with Trypanosoma cruzi

1993 • 9 citations