Accumulation of p53 protein correlates with tumour proliferative activity in EBV positive Burkitt's lymphoma

Mutations in the p53 gene occur in diverse human tumour types

1989 • 2,765 citations

T antigen is bound to a host protein in SY40-transformed cells

1979 • 2,378 citations

Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa

1991 • 1,418 citations

Increased expression of mutant forms of p53 oncogene in primary lung cancer

1990 • 1,045 citations

p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia.

1991 • 915 citations

p53: oncogene or anti-oncogene?

1990 • 812 citations

Flow cytometry in clinical cancer research.

1983 • 764 citations

Accumulation of p53 Tumor Suppressor Gene Protein: An Independent Marker of Prognosis in Breast Cancers

1992 • 757 citations

Evolution of tumours and the impact of molecular oncology

1985 • 666 citations

Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation

1991 • 617 citations

Analysis of PCP-data to determine the fraction of cells in the various phases of cell cycle

1975 • 586 citations

Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23

1990 • 585 citations

Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies.

1991 • 512 citations

Association of Overexpression of Tumor Suppressor Protien p53 With Rapid Cell Proliferation and Poor Prognosis in Node-Negative Breast Cancer Patients

1992 • 349 citations

Small Subgroup of Aggressive, Highly Proliferative Prostatic Carcinomas Defined by p53 Accumulation

1992 • 317 citations

Genetic basis for p53 overexpression in human breast cancer.

1991 • 287 citations

p53 is frequently mutated in Burkitt's lymphoma cell lines.

1991 • 259 citations

Overproduction of p53 antigen makes established cells highly tumorigenic

1985 • 217 citations

The p53 protein and its interactions with the oncogene products of the small DNA tumor viruses

1990 • 200 citations

Expression of the nuclear oncogene p53 in colon tumours

1989 • 173 citations

p53 mutations in ovarian cancer: a late event?

1991 • 151 citations

The Epstein-Barr Virus Proteins

1988 • 109 citations

Simultaneous monitoring of P53 protein and dna content of colorectal adenocarcinomas by flow cytometry

1990 • 81 citations

Purification and biochemical characterization of the Epstein-Barr virus-determined nuclear antigen and an associated protein with a 53,000-dalton subunit

1980 • 77 citations

Mutant p53 detected in a majority of Burkitt lymphoma cell lines by monoclonal antibody PAb240.

1991 • 74 citations

Flow cytometric DNA analysis of 199 histologically favourable or unfavourable non‐Hodgkin lymphomas

1989 • 51 citations

Modulation of cellular gene expression in B lymphoma cells following in vitro infection by Epstein‐Barr virus (EBV)

1990 • 42 citations

Non-isotopic detection of in situ nucleic acid in cervix: an updated protocol.

1988 • 41 citations

Chromosome translocation and c-MY Cactivation by Epstein-Barr virus and Euphorbia tirucalli in B lymphocytes

1991 • 33 citations

A 53-kilodalton protein common to chemically and virally transformed cells shows extensive sequence similarities between species.

1982 • 23 citations

Nuclear DNA content of non-endemic Burkitt's lymphoma.

1987 • 14 citations

Small non-cleaved follicular center cell lymphoma: Clinicopathologic comparison of Burkitt and non-Burkitt variants in finnish material

1985 • 8 citations

Quantity of nuclear DNA in malignancies and benign lymphadenopathies associated with Epstein-Barr virus.

1989 • 6 citations