Biochemical and molecular properties of lithium-sensitive myo-inositol monophosphatase

Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C

1992 • 4,480 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain.

1980 • 1,099 citations

Neural and developmental actions of lithium: A unifying hypothesis

1989 • 1,005 citations

Regulation of inositol phospholipid-specific phospholipase C isozymes.

1992 • 740 citations

Role of phosphoinositides in transmembrane signaling.

1990 • 491 citations

INOSITOL PHOSPHATE BIOCHEMISTRY

1992 • 402 citations

Metabolism of the inositol phosphates produced upon receptor activation

1989 • 305 citations

Two distinct cDNAs for human IMP dehydrogenase.

1990 • 256 citations

d-Myoinositol 1-Phosphate as Product of Cyclization of Glucose 6-Phosphate and Substrate for a Specific Phosphatase in Rat Testis

1967 • 252 citations

Effects of Systemically Administered Lithium on Phosphoinositide Metabolism in Rat Brain, Kidney, and Testis

1985 • 186 citations

The purification and properties of myo-inositol monophosphatase from bovine brain

1988 • 174 citations

DNA sequence, organization and regulation of the qa gene cluster of Neurospora crassa

1989 • 160 citations

Why is uncompetitive inhibition so rare?

1986 • 156 citations

Second messenger systems and psychoactive drug action: focus on the phosphoinositide system and lithium

1989 • 142 citations

Inositol polyphosphate 1-phosphatase from calf brain. Purification and inhibition by Li+, Ca2+, and Mn2+.

1987 • 128 citations

“Thrombin” receptor-directed ligand accounts for activation by thrombin of platelet phospholipase C and accumulation of 3-phosphorylated phosphoinositides.

1991 • 119 citations

Biosynthesis of myo-inositol in rat mammary gland. Isolation and properties of the enzymes

1974 • 115 citations

Cloning and expression of bovine brain inositol monophosphatase.

1990 • 107 citations

cDNA cloning of human and rat brain myo-inositol monophosphatase. Expression and characterization of the human recombinant enzyme

1992 • 101 citations

The inositol phospholipids: a stereochemical view of biological activity

1986 • 96 citations

Lithium-Sensitive Production of Inositol Phosphates During Amphibian Embryonic Mesoderm Induction

1992 • 94 citations

Chemical and kinetic mechanism of the inositol monophosphatase reaction and its inhibition by Li⁺

1993 • 91 citations

Methods for the analysis of inositol phosphates

1989 • 89 citations

Purification and Properties of myo-Inositol-1-Phosphatase from Rat Brain

1985 • 86 citations

Molecular organisation of the quinic acid utilization (QUT) gene cluster in Aspergillus nidulans

1988 • 84 citations

In Vitro and In Vivo Inhibition of Inositol Monophosphatase by the Bisphosphonate L‐690,330

1993 • 83 citations

Kinetic studies with myo-inositol monophosphatase from bovine brain

1990 • 72 citations

Purification and properties of myo-inositol-1-phosphatase from bovine brain

1988 • 63 citations

Probing the role of metal ions in the mechanism of inositol monophosphatase by site‐directed mutagenesis

1993 • 60 citations

A mutation that enhances synthesis of sigma 32 and suppresses temperature-sensitive growth of the rpoH15 mutant of Escherichia coli

1990 • 55 citations

Chronically Administered Lithium Alters Neither myo‐Inositol Monophosphatase Activity nor Phosphoinositide Levels in Rat Brain

1989 • 55 citations

Diverse proteins homologous to inositol monophosphatase

1991 • 48 citations

Measurement of biosynthesis of myo-inositol from glucose 6-phosphate

1987 • 46 citations

Cyclitols and Phosphoinositides

1979 • 46 citations

Expression of the Germ Cell Alkaline Phosphatase Gene in Human Choriocarcinoma Cells

1989 • 45 citations

Structural Similarities between Fructose-1,6-bisphosphatase and Inositol Monophosphatase

1993 • 43 citations

The identification of a novel inositol lipid, phosphatidylinostiol trisphosphate (PIP3), in rat cerebrum using in vivo techniques

1989 • 42 citations

Further Studies on myo-Inositol-1-phosphatase from the Pollen of Lilium longiflorum Thunb

1984 • 41 citations

Chronic dietary lithium induces increased levels of myo-inositol-1-phosphatase activity in rat cerebral cortex homogenates

1986 • 38 citations

Rapid purification of inositol monophosphate phosphatase from beef brain

1988 • 37 citations

A NOVEL INOSITOL MONO-PHOSPHATASE INHIBITOR FROM Memnoniella echinata

1992 • 33 citations

Ammonium transport in Escherichia coli: localization and nucleotide sequence of the amtA gene

1991 • 32 citations

Modification of myo-inositol monophosphatase by the arginine-specific reagent phenylglyoxal

1989 • 31 citations

Biochemical studies on inositol

1966 • 26 citations

Differential Uptake of Lithium Isotopes by Rat Cerebral Cortex and Its Effect on Inositol Phosphate Metabolism

1984 • 26 citations

Phylogeny of hemoglobins: The complete amino acid sequence of an α‐chain of viper (Vipera aspis) hemoglobin

1974 • 25 citations

myo-Inositol Monophosphatase from Rat Testes: Purification and Properties

1993 • 21 citations

Bovine inositol monophosphatase. Modification, identification and mutagenesis of reactive cysteine residues

1992 • 19 citations

Inositol-1-phosphatase of human erythrocytes is inhibited by therapeutic lithium concentrations

1989 • 19 citations

The effect of histidine modification on the activity of myo-inositol monophosphatase from bovine brain.

1992 • 17 citations

Reversible unfolding of myo-inositol monophosphatase.

1993 • 16 citations

Differential lethality of lithium isotopes in mice.

1980 • 16 citations

Dissimilar effects of lithium isotopes on motility in rats

1979 • 15 citations

Partial purification of inositol polyphosphate 1-phosphomonoesterase with characterization of its substrates and products by nuclear magnetic resonance spectroscopy

1989 • 15 citations

Inhibitors of myo-inositol monophosphatase containing methylenebisphosphonic acid as a replacement for a phosphate group

1991 • 14 citations

Identification and nucleotide sequence of the Leptospira biflexa serovar patoc trpE and trpG genes

1989 • 13 citations

Characteristics of the uptake of lithium isotopes into erythrocytes.

1979 • 13 citations

Inositol monophosphatase is a highly conserved enzyme having localized structural similarity to both glycerol 3-phosphate dehydrogenase and haemoglobin

1992 • 13 citations

Studies on avian erythrocyte metabolism: Purification and properties of myo-inositol 1-phosphatase from chick erythrocytes

1981 • 11 citations

Noncompetitive inhibition of inositol monophosphatase by K-76 monocarboxylic acid.

1991 • 11 citations

Lack of Differential Lethality of Lithium Isotopes in Mice

1984 • 10 citations

A monoclonal antibody to bovine brain inositol monophosphatase. Immunoaffinity purification of the brain and kidney enzymes and evidence for their structural identity

1989 • 10 citations

Beryllium competitively inhibits brain myo-inositol monophosphatase, but unlike lithium does not enhance agonist-induced inositol phosphate accumulation

1993 • 10 citations

Limited proteolysis and ‘in vitro’ mutagenesis of bovine brain inositol monophosphatase identifies an N-terminal region important for activity

1990 • 8 citations

Purification and properties of 2′-nucleotidase from mammalian brain

1979 • 8 citations

Bovine inositol monophosphatase: development of a continuous fluorescence assay of enzyme activity

1992 • 8 citations

The effects of lithium isotopes on the myo-inositol 1-phosphatase reaction in rat brain, liver, and testes

1992 • 8 citations

Structural characterization of myo-inositol monophosphatase from bovine brain by secondary structure prediction, fluorescence, circular dichroism and Raman spectroscopy

1993 • 7 citations

Bovine inositol monophosphatase

1993 • 6 citations

Inositol-1-Phosphatase in the Lens

1974 • 6 citations

Bovine inositol monophosphatase: proteolysis and structural studies

1993 • 5 citations

Assay of 1l-myo-inositol-1-phosphatase using a fluorometric method

1991 • 5 citations

Specificity constants for two-substrate enzymes

1993 • 5 citations

Specific staining of myo-inositol-1-phosphatase on polyacrylamide gels after electrophoresis

1989 • 4 citations

Partial purification and characterization of rat brain myo-inositol-1-phosphatase

1987 • 3 citations

Human brain 2′-nucleotidase: partial purification and properties

1986 • 1 citations