Intestinal Microbiota During Infancy and Its Implications for Obesity

An obesity-associated gut microbiome with increased capacity for energy harvest

2006 • 11,120 citations

Inflammation and metabolic disorders

2006 • 8,000 citations

Human gut microbes associated with obesity

2006 • 7,995 citations

Diversity of the Human Intestinal Microbial Flora

2005 • 7,395 citations

A core gut microbiome in obese and lean twins

2008 • 7,389 citations

Obesity alters gut microbial ecology

2005 • 5,818 citations

The gut microbiota as an environmental factor that regulates fat storage

2004 • 5,730 citations

Metabolic Endotoxemia Initiates Obesity and Insulin Resistance

2007 • 5,661 citations

Host-Bacterial Mutualism in the Human Intestine

2005 • 4,852 citations

Effects of Bariatric Surgery on Mortality in Swedish Obese Subjects

2007 • 4,380 citations

Microbial diversity in the deep sea and the underexplored “rare biosphere”

2006 • 3,619 citations

TLR4 links innate immunity and fatty acid–induced insulin resistance

2006 • 3,422 citations

A central role for JNK in obesity and insulin resistance

2002 • 3,225 citations

AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism

2005 • 2,774 citations

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

2008 • 2,750 citations

Development of the Human Infant Intestinal Microbiota

2007 • 2,714 citations

Mechanisms underlying the resistance to diet-induced obesity in germ-free mice

2007 • 2,435 citations

MICROBIAL ECOLOGY OF THE GASTROINTESTINAL TRACT

1977 • 2,394 citations

Factors Influencing the Composition of the Intestinal Microbiota in Early Infancy

2006 • 2,099 citations

A role for glucagon-like peptide-1 in the central regulation of feeding

1996 • 1,880 citations

Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ

2001 • 1,849 citations

IKK-β links inflammation to obesity-induced insulin resistance

2005 • 1,710 citations

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine V. Unitarian theory of the origin of the four epithelial cell types

1974 • 1,697 citations

Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia

2007 • 1,678 citations

H<scp>OW</scp>H<scp>OST</scp>-M<scp>ICROBIAL</scp>I<scp>NTERACTIONS</scp>S<scp>HAPE THE</scp>N<scp>UTRIENT</scp>E<scp>NVIRONMENT OF THE</scp>M<scp>AMMALIAN</scp>I<scp>NTESTINE</scp>

2002 • 1,558 citations

Developmental microbial ecology of the neonatal gastrointestinal tract

1999 • 1,344 citations

Error-correcting barcoded primers for pyrosequencing hundreds of samples in multiplex

2008 • 1,264 citations

The indigenous gastrointestinal microflora

1996 • 1,149 citations

Lipopolysaccharide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes

2006 • 976 citations

Gut Hormone Profiles Following Bariatric Surgery Favor an Anorectic State, Facilitate Weight Loss, and Improve Metabolic Parameters

2005 • 949 citations

Breast feeding and obesity: cross sectional study

1999 • 916 citations

Reduced Dietary Intake of Carbohydrates by Obese Subjects Results in Decreased Concentrations of Butyrate and Butyrate-Producing Bacteria in Feces

2006 • 888 citations

Comparative Metagenomics Revealed Commonly Enriched Gene Sets in Human Gut Microbiomes

2007 • 844 citations

Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis

2006 • 800 citations

Risk of Overweight Among Adolescents Who Were Breastfed as Infants

2001 • 797 citations

Gut Hormones as Mediators of Appetite and Weight Loss After Roux-en-Y Gastric Bypass

2007 • 701 citations

Truncated GLP-1 (proglucagon 78?107-amide) inhibits gastric and pancreatic functions in man

1993 • 661 citations

The Microbial Ecology of the Large Bowel of Breastfed and Formula-fed Infants During the First Year of Life

1982 • 633 citations

Characterization of the Fasting-induced Adipose Factor FIAF, a Novel Peroxisome Proliferator-activated Receptor Target Gene

2000 • 540 citations

Bacterial contributions to mammalian gut development

2004 • 529 citations

Development and Differences of Intestinal Flora in the Neonatal Period in Breast-Fed and Bottle-Fed Infants

1983 • 524 citations

The Gut and Energy Balance: Visceral Allies in the Obesity Wars

2005 • 524 citations

Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL

2007 • 511 citations

JNK1 in Hematopoietically Derived Cells Contributes to Diet-Induced Inflammation and Insulin Resistance without Affecting Obesity

2007 • 495 citations

PKC-θ knockout mice are protected from fat-induced insulin resistance

2004 • 459 citations

Association Between Infant Breastfeeding and Overweight in Young Children

2001 • 446 citations

Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells

2006 • 443 citations

Probiotic treatment of rat pups normalises corticosterone release and ameliorates colonic dysfunction induced by maternal separation

2007 • 432 citations

Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes

2006 • 427 citations

The Fasting-induced Adipose Factor/Angiopoietin-like Protein 4 Is Physically Associated with Lipoproteins and Governs Plasma Lipid Levels and Adiposity

2005 • 420 citations

Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects

2003 • 409 citations

Improvement of Glucose Tolerance and Hepatic Insulin Sensitivity by Oligofructose Requires a Functional Glucagon-Like Peptide 1 Receptor

2006 • 395 citations

Peroxisome Proliferator-Activated Receptor γ Target Gene Encoding a Novel Angiopoietin-Related Protein Associated with Adipose Differentiation

2000 • 388 citations

Oligofructose promotes satiety in healthy human: a pilot study

2005 • 380 citations

Quantification ofBifidobacteriumspp.,Escherichia coliandClostridium difficilein faecal samples of breast-fed and formula-fed infants by real-time PCR

2004 • 373 citations

PKC-θ knockout mice are protected from fat-induced insulin resistance

2004 • 373 citations

Angiopoietin-like protein 4 is a potent hyperlipidemia-inducing factor in mice and inhibitor of lipoprotein lipase

2002 • 356 citations

Long-term maintenance of species-specific bacterial microbiota in the basal metazoan Hydra

2007 • 326 citations

Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells.

1999 • 326 citations

The New Biology of Gastrointestinal Hormones

1998 • 323 citations

Prenatal Stress Alters Bacterial Colonization of the Gut in Infant Monkeys

2004 • 310 citations

Functional Genomic and Metabolic Studies of the Adaptations of a Prominent Adult Human Gut Symbiont, Bacteroides thetaiotaomicron, to the Suckling Period

2006 • 308 citations

Dietary non-digestible carbohydrates promote L-cell differentiation in the proximal colon of rats

2007 • 261 citations

Hepatic expression, synthesis and secretion of a novel fibrinogen/angiopoietin-related protein that prevents endothelial-cell apoptosis

2000 • 254 citations

The Piglet as a Model Animal for Studying Aspects of Digestion and Absorption in Milk-Fed Human Infants

2015 • 253 citations

Neonatal maternal separation predisposes adult rats to colonic barrier dysfunction in response to mild stress

2002 • 236 citations

Lipoprotein lipase: the regulation of tissue specific expression and its role in lipid and energy metabolism

2002 • 235 citations

Colonic fermentation influences lower esophageal sphincter function in gastroesophageal reflux disease

2003 • 223 citations

Human milk provides peptides highly stimulating the growth of bifidobacteria

2002 • 216 citations

Lipoprotein lipase controls fatty acid entry into adipose tissue, but fat mass is preserved by endogenous synthesis in mice deficient in adipose tissue lipoprotein lipase

1997 • 204 citations

Protective Nutrients and Bacterial Colonization in the Immature Human Gut

1999 • 203 citations

Involvement of endogenous glucagon-like peptide-1(7–36) amide on glycaemia-lowering effect of oligofructose in streptozotocin-treated rats

2005 • 200 citations

Influence of early feeding style on adiposity at 6 years of age

1990 • 178 citations

Microflora modulates endocrine cells in the gastrointestinal mucosa of the rat

1994 • 172 citations

Dietary Oligofructose Lessens Hepatic Steatosis, but Does Not Prevent Hypertriglyceridemia in Obese Zucker Rats

2000 • 170 citations

Development of the faecal anaerobic microflora after Caesarean section and treatment with antibiotics in newborn infants

1987 • 166 citations

Transmission of Mother’s Microflora to the Newborn at Birth

1996 • 162 citations

Bifidobacteria in the intestinal tract of infants: an in-vivo study

1976 • 162 citations

The functional interactions of commensal bacteria with intestinal secretory IgA

2007 • 150 citations

A place for dietary fibre in the management of the metabolic syndrome

2005 • 148 citations

Recollection of Childhood Events in Adults with Irritable Bowel Syndrome

1987 • 146 citations

Effects of mode of delivery and necrotising enterocolitis on the intestinal microflora in preterm infants

2004 • 125 citations

The Influence of Methods of Collection and Storage on the Bacteriology of Human Milk

1979 • 125 citations

Aerobic and Anaerobic Bacterial Flora of the Maternal Cervix and Newborn Gastric Fluid and Conjunctiva: A Prospective Study

1979 • 122 citations

Intestinal Flora of Infants

1983 • 118 citations

Roles of the Host Oxidative Immune Response and Bacterial Antioxidant Rubrerythrin during Porphyromonas gingivalis Infection

2006 • 116 citations

The origin of O serotypes of Escherichia coli in babies after normal delivery

1974 • 113 citations

Postnatal lymphatic partitioning from the blood vasculature in the small intestine requires fasting-induced adipose factor

2007 • 112 citations

Intestinal epithelial cell differentiation: new insights from mice, flies and nematodes

1995 • 89 citations

Microbial Flora of the Stomach after Gastric Bypass for Morbid Obesity

2007 • 65 citations

Molecular Mechanisms of Enteroendocrine Differentiaton

1998 • 62 citations

Bacterial colonization of the large intestine in newborns delivered by Cesarean section

1987 • 49 citations

Reduction of bacterial contamination in banked human milk

1979 • 49 citations

Prenatal Stress Alters Bacterial Colonization of the Gut in Infant Monkeys

2004 • 43 citations

Nutritional triggers for health and in disease

1992 • 41 citations

Escherichia coli isolated from babies delivered by caesarean section and their environment

1976 • 37 citations

Die Besiedlung von durch Kaiserschnitt entbundenen Säuglingen durch Escherichia coli

1976 • 25 citations

Induction of glucose competence in pancreatic beta cells by glucagon-like peptide-1(7-37).

1992 • 19 citations

Probiotic treatment of rat pups normalises corticosterone release and ameliorates colonic dysfunction induced by maternal separation (Gut (2007) 56, (1522-1528))

2008 • 17 citations

Vitamin K1 and K2 status and faecal flora in breast fed and formula fed 1-month-old infants

1993 • 14 citations