Induction of anomalous killing activity from antigen-specific CTL clones by adding high doses of human recombinant interleukin 2

Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.

1982 • 2,228 citations

H-2 compatability requirement for T-cell-mediated lysis of target cells infected with lymphocytic choriomeningitis virus. Different cytotoxic T-cell specificities are associated with structures coded for in H-2K or H-2D;.

1975 • 623 citations

A glycolipid on the surface of mouse natural killer cells

1980 • 539 citations

Lymphokine-activated killer cell phenomenon. II. Precursor phenotype is serologically distinct from peripheral T lymphocytes, memory cytotoxic thymus-derived lymphocytes, and natural killer cells

1983 • 477 citations

Lymphokine-activated killer cell phenomenon. III. Evidence that IL-2 is sufficient for direct activation of peripheral blood lymphocytes into lymphokine-activated killer cells.

1983 • 355 citations

Mixed Lymphocyte Cultures Produce Effector Cells: Model in vitro for Allograft Rejection

1970 • 230 citations

Lymphokine‐Driven “Differentiation” of Cytotoxic T‐Cell Clones into Cells with NK‐Like Specificity: Correlations with Display of Membrane Macromolecules

1983 • 158 citations

Studies on cytotoxicity generated in human mixed lymphocyte cultures. I. Time course and target spectrum of several distinct concomitant cytotoxic activities.

1978 • 149 citations

Reversible induction of natural killer cell activity in cloned murine cytotoxic T lymphocytes

1983 • 134 citations

Disappearance of the NK effect after explantation of lymphocytes and generation of similar nonspecific cytotoxicity correlated to the level of blastogenesis in activated cultures.

1980 • 109 citations

Studies on Cytotoxicity Generated in Human Mixed Lymphocyte Cultures

1978 • 93 citations

Qualitative and quantitative studies of antigen-presenting cell function by using I-A-expressing L cells.

1985 • 89 citations

Multiple activities of a cloned cell line mediating natural killer cell function.

1981 • 88 citations

Cytotoxicity of Human Peripheral Lymphocytes in Cell-Mediated Lympholysis; Antibody-Dependent Cell-Mediated Lympholysis and Natural Cytotoxicity Assays after Mixed Lymphocyte Culture

1978 • 66 citations

Cytotoxic Thy 1.2-Positive Blasts with NK-Like Target Selectivity in Murine Mixed Lymphocyte Cultures

1979 • 60 citations

Natural killer activity in cloned cytotoxic T lymphocytes: regulation by interleukin 2, interferon, and specific antigen.

1985 • 58 citations

Lymphokine-activated cell-associated antigen involved in broad-reactive killer cell-mediated cytotoxicity

1985 • 53 citations

Loss of specificity in cytolytic T lymphocyte clones obtained by limit dilution culture of Ly-2+ T cells.

1984 • 52 citations

T lymphocytes with promiscuous cytotoxicity

1976 • 47 citations

Conversion of specific to nonspecific cytotoxic T lymphocytes.

1986 • 26 citations

Functional heterogeneity in allospecific cytotoxic T lymphocyte clones. II. Development of syngeneic cytotoxicity in the absence of specific antigenic stimulation.

1985 • 24 citations

Generation of autoreactive cytotoxic T lymphocytes under limiting dilution conditions.

1983 • 23 citations

Degradation of specificity in cytolytic T lymphocyte clones: Mouse strain dependence and interstrain transfer of nonspecific cytolysis

1984 • 14 citations

The role of lymphokine-activated cell-associated antigen

1987 • 10 citations

Degradation of specificity in cytolytic T lymphocyte clones: two broad specificity, H‐2‐independent recognition systems, one natural killer‐like, develop during culture, in addition to the clonally distributed antigen‐specific receptor

1985 • 10 citations

Significant frequency of cytotoxic T lymphocyte precursor cells specific for TNP-modified allogeneic cells in normal lymphocytes

1986 • 5 citations