Characterisation of two new monoclonal antibodies directed against rat microglia

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

Histochemistry: Theoretical and Applied

1953 • 7,198 citations

Adhesion receptors of the immune system

1990 • 6,585 citations

Reactive microglia are positive for HLA‐DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

1988 • 2,754 citations

The Glomerular Permeability Determined by Dextran Clearance Using Sephadex Gel Filtration

1968 • 2,659 citations

Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain

1990 • 1,897 citations

HISTOCHEMISTRY, THEORETICAL AND APPLIED

1969 • 1,640 citations

The Heterogeneity of Mononuclear Phagocytes in Lymphoid Organs: Distinct Macrophage Subpopulations in Rat Recognized by Monoclonal Antibodies ED1, ED2 and ED3

1985 • 1,605 citations

F4/80, a monoclonal antibody directed specifically against the mouse macrophage

1981 • 1,582 citations

Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescence

1972 • 1,456 citations

Perivascular Microglial Cells of the CNS Are Bone Marrow-Derived and Present Antigen in Vivo

1988 • 1,451 citations

The fine structure of the nervous system: The neurons and supporting cells

1976 • 1,334 citations

Characterization of ameboid microglia isolated from developing mammalian brain

1986 • 1,287 citations

Cytology & cellular pathology of the nervous system

1965 • 1,037 citations

Functional plasticity of microglia: A review

1988 • 931 citations

Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease

1989 • 904 citations

Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain

1985 • 881 citations

Interleukin-1 Stimulation of Astroglial Proliferation After Brain Injury

1985 • 855 citations

Displacement of synaptic terminals from regenerating motoneurons by microglial cells

1968 • 845 citations

Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: Differentiation antigens of rat lymphocytes

1977 • 777 citations

Two types of astrocytes in cultures of developing rat white matter: differences in morphology, surface gangliosides, and growth characteristics

1983 • 758 citations

Macrophages and microglia in the nervous system

1988 • 742 citations

Identification of Ia glycoproteins in rat thymus and purification from rat spleen

1979 • 682 citations

Encyclopedia of Neuroscience

1988 • 681 citations

Ia antigen expression on human epidermal Langerhans cells

1977 • 603 citations

Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3.

1986 • 602 citations

The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain

1989 • 504 citations

Lectin binding by resting and reactive microglia

1987 • 497 citations

Brain microglia constitutively express β-2 integrins

1990 • 423 citations

Expression of the histocompatibility glycoprotein HLA-DR in neurological disease

1988 • 397 citations

Response of endogenous glial cells to motor neuron degeneration induced by toxic ricin

1988 • 390 citations

The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues.

1981 • 389 citations

An improved staining method for rat microglial cells using the lectin from Griffonia simplicifolia (GSA I-B4).

1990 • 380 citations

Axotomy of the rat facial nerve leads to increased CR3 complement receptor expression by activated microglial cells

1988 • 368 citations

Mouse monoclonal antibodies against rat major histocompatibility antigens. Two Ia antigens and expression of Ia and class I antigens in rat thymus

1982 • 364 citations

Migration of Hematogenous Cells Through the Blood‐Brain Barrier and the Initiation of CNS Inflammation

1991 • 362 citations

A novel myelin-associated glycoprotein defined by a mouse monoclonal antibody

1984 • 318 citations

Macrophages can modify the nonpermissive nature of the adult mammalian central nervous system

1990 • 308 citations

Expression of Ia antigen on perivascular and microglial cells after sublethal and lethal motor neuron injury

1989 • 289 citations

Identity of ED2‐positive perivascular cells in rat brain

1989 • 281 citations

Astrocyte heterogeneity

1990 • 254 citations

Cytology and Cellular Pathology of the Nervous System.

1932 • 245 citations

Intrathecal application of interferon gamma. Progressive appearance of MHC antigens within the rat nervous system.

1990 • 240 citations

Monoclonal antibodies to desmin, the muscle-specific intermediate filament protein.

1983 • 239 citations

A monoclonal antibody to a differentiation antigen present on mature human macrophages and absent from monocytes.

1985 • 238 citations

Modulation of CD4 antigen on macrophages and microglia in rat brain.

1987 • 229 citations

Neuroimmune networks: physiology and diseases

1990 • 228 citations

An autoradiographic study of the incorporation of nucleic-acid precursors by neurones and glia during nerve regeneration.

1965 • 226 citations

A third neuroglial cell types. An electron microscopic study

1968 • 217 citations

New expression of myelomonocytic antigens by microglia and perivascular cells following lethal motor neuron injury

1990 • 213 citations

Immunohistochemical analysis of the rat central nervous system during experimental allergic encephalomyelitis, with special reference to Ia-positive cells with dendritic morphology.

1986 • 204 citations

Microglia: Immune Network in the CNS

1990 • 200 citations

Peripheral nerve lesion produces increased levels of major histocompatibility complex antigens in the central nervous system

1989 • 189 citations

Cholinergic sprouting in the hippocampus: A proposed role for IL-1

1990 • 187 citations

Ia Antigens in Mouse Skin Are Predominantly Expressed on Langerhans Cells

1979 • 185 citations

On the interdigitating cells in the thymus-dependent area of the rat spleen: A relation between the mononuclear phagocyte system and T-lymphocytes

1974 • 181 citations

Microglial cells around amyloid plaques in Alzheimer's disease express leucocyte adhesion molecules of the LFA-1 family

1989 • 174 citations

Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.

1984 • 160 citations

5?-Nucleotidase of microglial cells in the facial nucleus during axonal reaction

1978 • 144 citations

Lesion of the rat entorhinal cortex leads to a rapid microglial reaction in the dentate gyrus

1991 • 142 citations

Heterogeneity of mononuclear phagocytes

1982 • 141 citations

Microglia in the giant cell encephalitis of acquired immune deficiency syndrome: proliferation, infection and fusion

1988 • 140 citations

Proliferative changes in glial cells during nerve regeneration

1965 • 133 citations

Autoradiographische Untersuchung �ber die Beteiligung von Gliazellen an der axonalen Reaktion im Facialiskern der Ratte

1966 • 132 citations

Monocyte subpopulations in human gliomas: expression of Fc and complement receptors and correlation with tumor proliferation

1990 • 131 citations

Microglia in the neurohypophysis associate with and endocytose terminal portions of neurosecretory neurons

1989 • 118 citations

Monoclonal antibody to macrophages (EMB/11) labels macrophages and microglial cells in human brain.

1986 • 114 citations

Macrophages in the central nervous system of the rat

1987 • 100 citations

Neuron-glial relationship during regeneration of motorneurons

1989 • 98 citations

Spinal cord microglial cells and DRG satellite cells rapidly respond to transection of the rat sciatic nerve

1991 • 92 citations

Heterogeneity of mononuclear phagocytes

1981 • 92 citations

Microglial mitogens are produced in the developing and injured mammalian brain.

1991 • 85 citations

Expression of Adhesion Molecules and Histocompatibility Antigens at the Blood‐Brain Barrier

1991 • 80 citations

Herpes simplex virus type I infection of the CNS induces major histocompatibility complex antigen expression on rat microglia

1990 • 79 citations

Juxtavascular karyokinesis and microglia cell proliferation during retrograde reaction in the mouse facial nucleus.

1965 • 75 citations

KI-M2R, a New Specific Monoclonal Antibody, Discriminates Tissue Macrophages From Reticulum Cells and Monocytes In Vivo and In Vitro

1985 • 74 citations

Respiratory burst activity in brain macrophages: a flow cytometric study on cultured rat microglia

1991 • 74 citations

One‐ and two‐dimensional electrophoresis in micro‐slab gels

1980 • 73 citations

The ontogenetic development of the follicular dendritic cell

1984 • 69 citations

Role of microglia in plaque formation in senile dementia of the Alzheimer type

1986 • 68 citations

Immunophenotypic characterization of rat brain macrophages in culture

1989 • 60 citations

Characteristics and functional aspects of nonlymphoid cells in rat germinal centers, recognized by two monoclonal antibodies ED5 and ED6

1986 • 46 citations

The Ultrastructure of Normal and Reactive Microglia

1975 • 44 citations

Heterogeneity of rat macrophages recognized by monoclonal antibodies: an immunohistochemical and immunoelectron microscopic study.

1989 • 43 citations

Characterization of nonlymphoid cells in rat spleen, with special reference to strongly Ia-positive branched cells in T-cell areas.

1982 • 34 citations

In situ Ia expression on brain cells in the rat: autoimmune encephalomyelitis-resistant strain (BN) and susceptible strain (Lewis) compared.

1989 • 32 citations

An Immunohistochemical and Immunoelectron Microscopic Study of the Ontogeny of Rat Langerhans Cell Lineage with Anti-Macrophage and Anti-Ia Monoclonal Antibodies

1989 • 28 citations

Analysis of Macrophage Differentiation and Function with Monoclonal Antibodies

1984 • 28 citations

Heterogeneity of macrophages in response to lymphokines and other signals

1982 • 21 citations

The Reticuloendothelial System

2001 • 16 citations

Lymphoid Dendritic Accessory Cells of the Rat

1990 • 15 citations

Immunohistochemical characterization of rat thymic non-lymphoid cells. II. Macrophages and granulocytes defined by monoclonal antibodies.

1990 • 12 citations

A monoclonal antibody raised against Alzheimer cortex that specifically recognizes a subpopulation of microglial cells.

1990 • 12 citations

Peripheral Nerve Development and Regeneration

1990 • 3 citations