Regulation of the human HOXD4 gene by retinoids

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

Homeobox genes and axial patterning

1992 • 2,688 citations

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

1992 • 1,252 citations

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.

1992 • 1,200 citations

Identification of a retinoic acid responsive element in the retinoic acid receptor & beta;gene

1990 • 1,018 citations

Luciferase reporter gene vectors for analysis of promoters and enhancers.

1988 • 1,016 citations

Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid

1991 • 1,007 citations

Identification and spatial distribution of retinoids in the developing chick limb bud

1987 • 964 citations

Multiplicity generates diversity in the retinoic acid signalling pathways

1992 • 836 citations

Transport and Storage of Vitamin A

1990 • 618 citations

Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells

1990 • 524 citations

Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo

1992 • 467 citations

Retinoic acid alters hindbrain Hox code and induces transformation of rhombomeres 2/3 into a 4/5 identity

1992 • 461 citations

Retinoids, homeoboxes, and growth factors: Toward molecular models for limb development

1991 • 410 citations

Expression of the homeobox Hox-4 genes and the specification of position in chick wing development

1991 • 394 citations

Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene

1992 • 364 citations

The human HOX gene family

1989 • 317 citations

Respecification of vertebral identities by retinoic acid

1992 • 312 citations

Targeted misexpression of Hox-4.6 in the avian limb bud causes apparent homeotic transformations

1992 • 307 citations

Polarizing activity and retinoid synthesis in the floor plate of the neural tube

1990 • 292 citations

Differential regulation by retinoic acid of the homeobox genes of the four HOX loci in human embryonal carcinoma cells

1991 • 291 citations

Homeotic transformation of the occipital bones of the skull by ectopic expression of a homeobox gene

1992 • 289 citations

Identification of a retinoic acid responsive enhancer 3′ of the murine homeobox gene Hox-1.6

1992 • 268 citations

Isolation of 3,4-didehydroretinoic acid, a novel morphogenetic signal in the chick wing bud

1990 • 252 citations

Regional differences in retinoid release from embryonic neural tissue detected by an in vitro reporter assay

1992 • 250 citations

The structure of the homeodomain and its functional implications

1990 • 233 citations

Involvement of the Chox-4 chicken homeobox genes in determination of anteroposterior axial polarity during limb development

1991 • 223 citations

Evidence that Hensen's node is a site of retinoic acid synthesis

1992 • 216 citations

Differential and stage-related expression in embryonic tissues of a new human homoeobox gene

1986 • 182 citations

The vertebrate limb: A model system to study the Hox/hom gene network during development and evolution

1992 • 175 citations

Deciphering the Hox code: Clues to patterning branchial regions of the head

1991 • 164 citations

Homeotic transformations in the mouse induced by overexpression of a human Hox3.3 transgene

1992 • 160 citations

Identification of a retinoic acid response element upstream of the murine Hox-4.2 gene.

1993 • 139 citations

Activation of four homeobox gene clusters in human embryonal carcinoma cells induced to differentiate by retinoic acid

1988 • 135 citations

The expression of murine Hox-2 genes id dependent on the differenation pathway and displays a collinear sensitivity to retinoic acid in F9 cels andXenopusembroys

1991 • 119 citations

An autoregulatory element of the murine Hox-4.2 gene.

1992 • 107 citations

Expression of a homeobox gene in the chick wing bud following application of retinoic acid and grafts of polarizing region tissue.

1990 • 106 citations

A human HOX4B regulatory element provides head-specific expression in Drosophila embryos

1992 • 100 citations

Retinoic acid, a developmental signalling molecule

1990 • 93 citations

The upstream region of the human homeobox gene HOX3D is a target for regulation by retinoic acid and HOX homeoproteins.

1992 • 85 citations

Regulation of vertebrate homeobox‐containing genes by morphogens

1993 • 76 citations

Region-specific enhancers near two mammalian homeo box genes define adjacent rostrocaudal domains in the central nervous system.

1990 • 76 citations

Human homeo box-containing genes located at chromosome regions 2q31----2q37 and 12q12----12q13.

1987 • 73 citations

Retinoids: 10 Years On

1991 • 66 citations

Molecular mechanisms underlying the expression of the human HOX-5.1 gene

1990 • 47 citations