Induction of haemoglobin synthesis in the human leukaemia cell line K562 by monomethyltriazenes and imidazotetrazinones

Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome

1975 • 2,865 citations

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

1983 • 2,392 citations

Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome

1975 • 2,228 citations

DNA Methylation and Gene Function

1980 • 2,069 citations

Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine.

1982 • 575 citations

Properties of the K562 cell line, derived from a patient with chronic myeloid leukemia

1976 • 412 citations

Antitumour imidazotetrazines. 1. Synthesis and chemistry of 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one, a novel broad-spectrum antitumor agent

1984 • 212 citations

Myeloid and megakaryocytic properties of K-562 cell lines.

1983 • 146 citations

Tumour inhibitory triazenes: Structural requirements for an active metabolite

1976 • 122 citations

Studies on the mechanism of action of the tumour inhibitory triazenes

1973 • 88 citations

DNA methylation and methylase levels in normal and malignant mouse hepatic tissues

1981 • 60 citations

Mechanism of carcinogenesis with 1-aryl-3,3-dialkyltriazenes—II in vitro-alkylation of guanosine, RNA and DNA with aryl-monoalkyltriazenes to form 7-alkylguanine

1970 • 44 citations

DNA methylase inhibition in vitro by N-methyl-N'-nitro-N-nitrosoguanidine.

1980 • 38 citations

Studies of the mode of action of antitumour triazenes and triazines—II. Investigation of the selective toxicity of 1-aryl-3,3-dimethyltriazenes

1981 • 30 citations

Induction of hemoglobin synthesis in human leukemic K 562 cells by adriamycin.

1984 • 28 citations

Induction of leukemia cell differentiation by chemotherapeutic agents

1983 • 26 citations

Impaired restriction endonuclease cleavage of DNA modified with N-methyl-N-nitrosourea

1980 • 14 citations

Induction of morphological differentiation in cultured mouse neuroblastoma cells by alkylating agents

1982 • 12 citations

Induction of differentiation in cultured mouse neuroblastoma cells by N-methyl-N′-nitro-N-nitrosoguanidine

1979 • 6 citations