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Studies on the mechanism of action of the tumour inhibitory triazenes

Data up to Jan 2025

Published1973
Citations88
References21

Total Citations Per Year

Abstract

References (21)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Tissue sulfhydryl groups

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Biochemical and pharmacological changes in the rat following chronic administration of morphine nalorphine and normorphine.

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A COLORIMETRIC DETERMINATION OF ACETALDEHYDE IN BLOOD

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CHEMICAL STRUCTURE AND CARCINOGENICITY OF ALIPHATIC HYDRAZO, AZO, AND AZOXY COMPOUNDS AND OF TRIAZENES, POTENTIAL IN VIVO ALKYLATING AGENTS*

1969 • 137 citations

5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamide (DTIC, DIC, NSC-45388)—A new antitumor agent with activity against malignant melanoma

1972 • 119 citations

Antitumor activity of triazenoimidazoles

1962 • 82 citations

Fundamentals of biochemical pharmacology

1971 • 73 citations

Methylation of nucleic acids and urinary excretion of 14C-labeled 7-methylguanine by rats and man after administration of 4(5)-(3,3-Dimethyl-1-triazeno)-imidazole 5(4)-carboxomide

1971 • 62 citations

Mechanism of action of 5-(3,3-dimethyl-1-triazeno)imidazole-4-caboxamide in mammalian cells in culture

1972 • 47 citations

Syntheses and Biological Activity of 5-Aminoimidazoles and 5-Triazenoimidazoles

1970 • 41 citations

Aryl-2-halogenoalkylamines

1968 • 38 citations

Walker carcinosarcoma 256 in study of anticancer agents. I. Method for simultaneous assessment of therapeutic value and toxicity.

1966 • 31 citations

Preparation and antitumor activity of derivatives of 1-phenyl-3,3-dimethyltriazene

1972 • 26 citations

Studies on the reversal of the selective antitumour effect of the aziridinyl derivative cb 1954 by 4‐amino‐5‐imidazolecarboxamide

1972 • 25 citations

Observations on the metabolism of cyclophosphamide

1972 • 23 citations

PRECLINICAL INVESTIGATION OF ALKYLATING AGENTS IN CANCER CHEMOTHERAPY

1969 • 21 citations

Synthesis, Antileukemic Activity, and Stability Of 3-(Substituted-Triazeno)pyrazole-4-carboxylic Acid Esters and 3-(Substituted-Triazeno)pyrazole-4-carboxamides

1971 • 20 citations

Role of 4-diazoimidazole-5-carboxamide in the action of the antitumor agent 5(4)-(3,3-dimethyl-1-triazeno) imidazole-4-(5)carboxa-mide in Bacillus subtilis

1972 • 18 citations

The Effect of Asparaginase on Some Animal-Tumors

1970 • 7 citations

Serum Turbidity Responses of Anti-Inflammatory Drugs in Endocrine-Deficient Rats

1968 • 1 citations

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Studies on the mechanism of action of the tumour inhibitory triazenes (1973) – Biochemical Pharmacology | Metascience Observatory Explorer