The isolation of a human Ig Vλ gene from a recombinant library of chromosome 22 and estimation of its copy number

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

1973 • 4,217 citations

A membrane-filter technique for the detection of complementary DNA

1966 • 3,996 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

The use of thin acrylamide gels for DNA sequencing

1978 • 1,449 citations

AN ANALYSIS OF THE SEQUENCES OF THE VARIABLE REGIONS OF BENCE JONES PROTEINS AND MYELOMA LIGHT CHAINS AND THEIR IMPLICATIONS FOR ANTIBODY COMPLEMENTARITY

1970 • 1,308 citations

Characteristic chromosomal abnormalities in biopsies and lymphoid‐cell lines from patients with burkitt and non‐burkitt lymphomas

1976 • 864 citations

Sequences at the somatic recombination sites of immunoglobulin light-chain genes

1979 • 859 citations

The role of gene dosage and genetic transpositions in carcinogenesis

1981 • 670 citations

Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements

1984 • 669 citations

A complete immunoglobulin gene is created by somatic recombination.

1978 • 610 citations

Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene.

1979 • 472 citations

Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain.

1978 • 419 citations

Clustered arrangement of immunoglobulin λ constant region genes in man

1981 • 379 citations

Reduction in the rate of DNA reassociation by sequence divergence

1973 • 374 citations

Immunoglobulin Genes

1983 • 341 citations

Chromosomal location of human kappa and lambda immunoglobulin light chain constant region genes

1982 • 292 citations

Localization of human immunoglobulin kappa light chain variable region genes to the short arm of chromosome 2 by in situ hybridization.

1982 • 242 citations

Structure and multiplicity of genes for the human immunoglobulin heavy chain variable region.

1980 • 199 citations

Construction and characterization of genomic libraries from specific human chromosomes.

1982 • 142 citations

Genes for immunoglobulin heavy chains and for α1-antitrypsin are localized to specific regions of chromosome 14q

1982 • 139 citations

Organization of four mouse lambda light chain immunoglobulin genes.

1981 • 127 citations

Biosynthesis and Regulation of Immunoglobulins

1983 • 119 citations

Human Vκ immunoglobulin gene number: Implications for the origin of antibody diversity

1981 • 111 citations

Localization of human variable and constant region immunoglobulin heavy chain genes on subtelomeric band q32 of chromosome 14

1982 • 101 citations

Amplified C lambda and c-abl genes are on the same marker chromosome in K562 leukemia cells.

1983 • 92 citations

Primary structures of N-terminal extra peptide segments linked to the variable and constant regions of immunoglobulin light chain precursors: implications on the organization and controlled expression of immunoglobulin genes

1978 • 80 citations

Lambda lg constant region genes are translocated to chromosome 8 in Burkitt's lymphoma with t(8:22

1983 • 61 citations

The breakpoint of the Philadelphia chromosome 22 in chronic myeloid leukaemia is distal to the immunoglobulin lambda light chain constant region genes.

1983 • 30 citations

Sequence variability at the N-terminal leader peptides of rat immunoglobulin light chain precursors

1982 • 1 citations