11β-Hydroxysteroid Dehydrogenase Type 1 from Human Liver: Dimerization and Enzyme Cooperativity Support Its Postulated Role as Glucocorticoid Reductase

Basic local alignment search tool

1990 • 87,358 citations

Genetic and Nongenetic Determinants of Regional Fat Distribution

1993 • 464 citations

Cloning and Expression of Rat cDNA Encoding Corticosteroid 11β-Dehydrogenase

1989 • 452 citations

The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization.

1991 • 434 citations

GLUCOCORTICOID AND MINERALOCORTICOID RECEPTORS: Biology and Clinical Relevance

1997 • 313 citations

Human 3α-hydroxysteroid dehydrogenase isoforms (AKR1C1–AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

2000 • 309 citations

11 beta-hydroxysteroid dehydrogenase is an exclusive 11 beta- reductase in primary cultures of rat hepatocytes: effect of physicochemical and hormonal manipulations.

1995 • 301 citations

Human placental 11 beta-hydroxysteroid dehydrogenase: evidence for and partial purification of a distinct NAD-dependent isoform.

1993 • 263 citations

11β-Hydroxysteroid Dehydrogenase in the Brain: A Novel Regulator of Glucocorticoid Action?

1997 • 212 citations

SDR and MDR: completed genome sequences show these protein families to be large, of old origin, and of complex nature

1999 • 197 citations

Mineralocorticoid activity of carbenoxolone: contrasting effects of carbenoxolone and liquorice on 11β-hydroxysteroid dehydrogenase activity in man

1990 • 187 citations

A guide to 17β-hydroxysteroid dehydrogenases

2001 • 160 citations

11β-hydroxysteroid dehydrogenase 1 in adipocytes: Expression is differentiation-dependent and hormonally regulated

1998 • 119 citations

The Crystal Structure of 3α-Hydroxysteroid Dehydrogenase/Carbonyl Reductase from Comamonas testosteroni Shows a Novel Oligomerization Pattern within the Short Chain Dehydrogenase/Reductase Family

2000 • 106 citations

Corticosteroids, receptors, and the organ‐specific functions of 11 β ‐hydroxysteroid dehydrogenase

1991 • 104 citations

11β-hydroxysteroid dehydrogenase type 1 expression in 2S FAZA hepatoma cells is hormonally regulated: a model system for the study of hepatic glucocorticoid metabolism

1996 • 95 citations

cDNA Cloning and Characterization of a cis-Retinol/3α-Hydroxysterol Short-chain Dehydrogenase

1997 • 88 citations

Control of terminal differentiation of adipose precursor cells by glucocorticoids

1991 • 82 citations

Regulation of 11 beta-hydroxysteroid dehydrogenase type 1 in primary cultures of rat and human hepatocytes

1998 • 79 citations

The purification of 11β-hydroxysteroid dehydrogenase from mouse liver microsomes

1994 • 52 citations

Three‐dimensional model of NAD⁺‐dependent 15‐hydroxyprostaglandin dehydrogenase and relationships to the NADP⁺‐dependent enzyme (carbonyl reductase)

1993 • 45 citations

Structures important in mammalian 11β- and 17β-hydroxysteroid dehydrogenases

1995 • 22 citations