SDR and MDR: completed genome sequences show these protein families to be large, of old origin, and of complex nature

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

The Complete Genome Sequence of Escherichia coli K-12

1997 • 7,325 citations

The PROSITE database, its status in 1997

1997 • 1,783 citations

Short-chain dehydrogenases/reductases (SDR)

1995 • 1,228 citations

Interaction of pyrophosphate moieties with .alpha.-helixes in dinucleotide-binding proteins

1985 • 475 citations

Active-site zinc ligands and activated H2O of zinc enzymes.

1990 • 432 citations

Involvement of Alcohol Dehydrogenase, Short-Chain Dehydrogenase/Reductase, Aldehyde Dehydrogenase, and Cytochrome P450 in the Control of Retinoid Signaling by Activation of Retinoic Acid Synthesis

1996 • 271 citations

Alcohol and polyol dehydrogenases are both divided into two protein types, and structural properties cross-relate the different enzyme activities within each type.

1981 • 237 citations

Three-dimensional structure of holo 3 alpha,20 beta-hydroxysteroid dehydrogenase: a member of a short-chain dehydrogenase family.

1991 • 232 citations

The SWISS-PROT protein sequence data bank and its supplement TrEMBL in 1998

1998 • 222 citations

Structure and Catalytic Activity of Alcohol Dehydrogenases

1964 • 183 citations

The complete amino acid sequence of three alcohol dehydrogenase alleloenzymes (AdhN-11, AdhS and AdhUF) from the fruitfly Drosophila melanogaster

1980 • 180 citations

A Super-Family of Medium-Chain Dehydrogenases/Reductases (MDR). Sub-Lines including zeta-Crystallin, Alcohol and Polyol Dehydrogenases, Quinone Oxidoreductases, Enoyl Reductases, VAT-1 and other Proteins

1994 • 154 citations

Evolution of the cytochrome P450 superfamily: sequence alignments and pharmacogenetics

1998 • 150 citations

Isolation and DNA Sequence of ADH3, a Nuclear Gene Encoding the Mitochondrial Isozyme of Alcohol Dehydrogenase in Saccharomyces cerevisiae

1985 • 146 citations

NOMENCLATURE OF ALCOHOL DEHYDROGENASES

1995 • 142 citations

Molecular aspects of functional differences between alcohol and sorbitol dehydrogenases

1985 • 140 citations

A Super‐Family of Medium‐Chain Dehydrogenases/Reductases (MDR)

1994 • 131 citations

Cloning and sequence analysis of the fermentative alcohol-dehydrogenase-encoding gene of Escherichia coli

1989 • 125 citations

Isolation and DNA sequence of ADH3, a nuclear gene encoding the mitochondrial isozyme of alcohol dehydrogenase in Saccharomyces cerevisiae.

1985 • 115 citations

Crystal Structure ofEscherichia coliQOR Quinone Oxidoreductase Complexed with NADPH

1995 • 114 citations

Purification and structural characterization of placental NAD+-linked 15-hydroxyprostaglandin dehydrogenase. The primary structure reveals the enzyme to belong to the short-chain alcohol dehydrogenase family

1990 • 105 citations

Escherichia coli mutants with altered control of alcohol dehydrogenase and nitrate reductase

1980 • 104 citations

Eye lens .zeta.-crystallin relationships to the family of "long-chain" alcohol/polyol dehydrogenases. Protein trimming and conservation of stable parts

1989 • 91 citations

Structural Analyses of Mutant and Wild-Type Alcohol Dehydrogenases from Drosophila melanogaster

1976 • 75 citations

Pea formaldehyde-active class III alcohol dehydrogenase: common derivation of the plant and animal forms but not of the corresponding ethanol-active forms (classes I and P).

1996 • 64 citations

Mycothiol‐Dependent Formaldehyde Dehydrogenase, A Prokaryotic Medium‐Chain Dehydrogenase/Reductase, Phylogenetically Links Different Eukaroytic Alcohol Dehydrogenases Primary Structure, Conformational Modelling and Functional Correlations

1997 • 51 citations

Genetic regulation of liver alcohol dehydrogenase in Peromyscus

1978 • 45 citations

Partial Similarities Between Yeast and Liver Alcohol Dehydrogenases

1973 • 41 citations

Cephalopod alcohol dehydrogenase: purification and enzymatic characterization

1993 • 24 citations