A molecular orbital study on the enzymic reaction mechanism of α-chymotrypsm

Approximate molecular orbital theory

1970 • 3,604 citations

Approximate Self-Consistent Molecular Orbital Theory. III. CNDO Results for AB2 and AB3 Systems

1966 • 1,906 citations

Role of a Buried Acid Group in the Mechanism of Action of Chymotrypsin

1969 • 1,060 citations

Mechanism of Action of Proteolytic Enzymes

1965 • 473 citations

Structure of crystalline α-chymotrypsin

1968 • 435 citations

Structure of crystalline α-chymotrypsin

1969 • 374 citations

Structure of crystalline α-chymotrypsin

1970 • 344 citations

Nonlinear structure-reactivity correlations. The reactivity of nucleophilic reagents toward esters

1968 • 331 citations

Theory of Substitution in Conjugated Molecules

1954 • 267 citations

The Current Status of the α-Chymotrypsin Mechanism

1964 • 195 citations

Oxygen Exchange as Evidence for the Existence of an Intermediate in Ester Hydrolysis

1951 • 190 citations

The Anatomy of an Enzymatic Catalysis. α-Chymotrypsin

1964 • 179 citations

The Correlation of the pH (pD) Dependence and the Stepwise Mechanism of α-Chymotrypsin-Catalyzed Reactions

1964 • 170 citations

MO-Theoretical Approach to the Mechanism of Charge Transfer in the Process of Aromatic Substitutions

1957 • 133 citations

The Effect of Substituents on the Deacylation of Benzoyl-Chymotrypsins

1962 • 113 citations

Atomic CO-ordinates for tosyl-α-chymotrypsin

1969 • 104 citations

The Identification of the Histidine Residue at the Active Center of Chymotrypsin

1965 • 102 citations

The Effect of Structure on the Rates of Some α-Chymotrypsin-catalyzed Reactions

1962 • 69 citations

Mechanism of the .alpha.-chymotrypsin-catalyzed hydrolysis of amides. pH dependence of kc and km. kinetic detection of an intermediate

1971 • 68 citations

The Concurrent Alkaline Hydrolysis and Isotopic Oxygen Exchange of a Series of p-Substituted Methyl Benzoates^1,2

1961 • 48 citations

Participation of an Acidic Group in the Chymotrypsin Catalysis***

1969 • 43 citations

Acyl substituent effects in the general base catalyzed ammonolysis reactions of esters

1969 • 42 citations

The Electronic Structures of Glycine in the Isolated State and in Water

1969 • 34 citations

Quantum-mechanical study on the photodimerization of aromatic molecules

1965 • 26 citations

The Electronic Structures of Base Components of Nucleic Acids and Their Tautomers Calculated by CNDO Method

1969 • 21 citations

A quantum mechanical study of the photodimerization of anthracene and its derivatives

1971 • 9 citations

Properties of the active center histidine of α-chymotrypsin

1972 • 4 citations