The Effect of Substituents on the Deacylation of Benzoyl-Chymotrypsins

USE OF GLASS ELECTRODES TO MEASURE ACIDITIES IN DEUTERIUM OXIDE^1,2

1960 • 2,132 citations

A Reëxamination of the Hammett Equation.

1953 • 2,102 citations

THE REACTION OF ACETYLCHOLINE AND OTHER CARBOXYLIC ACID DERIVATIVES WITH HYDROXYLAMINE, AND ITS ANALYTICAL APPLICATION

1949 • 1,902 citations

Mechanisms of Catalysis of Nucleophilic Reactions of Carboxylic Acid Derivatives.

1960 • 606 citations

Mechanism and Structure in Organic Chemistry

1973 • 438 citations

The reaction of p-nitrophenyl esters with chymotrypsin and insulin

1954 • 299 citations

General Base Catalysis of Ester Hydrolysis¹

1961 • 189 citations

Photooxidation of crystalline chymotrypsin in the presence of methylene blue

1953 • 184 citations

ACYLATION OF THE ENZYMATIC SITE OF δ-CHYMOTRYPSIN BY ESTERS, ACID ANHYDRIDES, AND ACID CHLORIDES

1957 • 155 citations

Imidazole Catalysis. I. The Catalysis of the Hydrolysis of Phenyl Acetates by Imidazole

1957 • 146 citations

Imidazole Catalysis

1959 • 142 citations

The inhibition of erythrocyte cholinesterase by tri-esters of phosphoric acid. 1. Diethyl p-nitrophenyl phosphate (E 600) and analogues

1952 • 141 citations

General Base Catalysis of the Aminolysis of Phenyl Acetate¹

1960 • 136 citations

The influence of structure on the hydrolysis of substituted phenyl β-<scp>d</scp>-glucosides by emulsin

1954 • 120 citations

The Mechanism of Aminolysis of Esters^1,2

1960 • 108 citations

The hydrolysis of esters of phenol by cholinesterases and other esterases

1953 • 107 citations

Effect of pH on the activity of eel esterase towards different substrates

1958 • 102 citations

The thermally induced configurational change of ribonuclease in H2O and D2O

1959 • 101 citations

Effect of Deuterium on the Strength of Hydrogen Bonds¹

1959 • 97 citations

A new method for labelling the active center of chymotrypsin

1962 • 95 citations

A Symposium on the Mechanism of Enzyme Action

1954 • 95 citations

The Mechanism of Chymotrypsin-catalyzed Reactions. III

1959 • 86 citations

The Influence of the Leaving Tendency of the Phenoxy Group on the Ammonolysis and Hydrolysis of Substituted Phenyl Acetates

1960 • 85 citations

Proposed Mechanism of Action of Hydrolytic Enzymes

1957 • 75 citations

Reactivity and Catalysis in Reactions of the Serine Hydroxyl Group and of O-Acyl Serines

1961 • 73 citations

Imidazole Catalysis

1959 • 71 citations

Intramolecular Carboxylate Attack on Ester Groups. The Hydrolysis of Substituted Phenyl Acid Succinates and Phenyl Acid Glutarates¹

1960 • 70 citations

The Effect of Structure on the Rates of Some α-Chymotrypsin-catalyzed Reactions

1962 • 69 citations

Imidazole Catalysis. V. The Intramolecular Participation of the Imidazolyl Group in the Hydrolysis of Some Esters and the Amide of γ-(4-Imidazolyl)-butyric Acid and 4-(2'-Acetoxyethyl)-imidazole²

1959 • 57 citations

Deuterium Oxide Solvent Isotope Effects in the Nucleophilic Reactions of Phenyl Esters

1962 • 51 citations

Aromatic N-deacylation by chick-kidney mitochondria

1960 • 49 citations

The action of N-bromosuccinimide on chymotrypsin

1961 • 45 citations

ANALOGUES OF ACETYL CHYMOTRYPSIN

1957 • 45 citations

The hydrolysis of peptide and ester bonds by proteolytic enzymes

1959 • 44 citations

Studies on sulphatases. 13. The hydrolysis of substituted phenyl sulphates by the arylsulphatase of Alcaligenes metalcaligenes

1956 • 43 citations

SPECIFIC REACTIONS OF DINITROFLUOROBENZENE WITH ACTIVE GROUPS OF CHYMOTRYPSIN

1956 • 39 citations

Characterization of the Difference Spectrum of Diisopropylphosphoryl-α-chymotrypsin versus α-Chymotrypsin. III. Spectrophotometric Titration of Tyrosyl Groups

1962 • 34 citations

The chemical kinetics of some reactions catalyzed by pancreatic carboxypeptidase

1955 • 29 citations

AN INTERMEDIATE IN THE DEACETYLATION OF MONO-ACETYL-δ-CHYMOTRYPSIN HAVING THE PROPERTIES OF ACETYL-IMIDAZOLYL¹

1957 • 26 citations

Rates of Solvolysis of the m- and p-Phenyl-, m- and p-Methylthio-, and m- and p- Trimethylsilylphenyldimethylcarbinyl Chlorides. Steric Inhibition of Resonance as a Factor in Electrophilic Substituent Constants^1,2

1958 • 25 citations

Introduction to the symposium on enzyme reaction mechanisms

1959 • 23 citations

Imidazole Catalysis. VII. The Dependence of Imidazole Catalysis of Ester Hydrolysis on the Nature of the Acyl Group¹

1960 • 23 citations

The function of neighboring groups and side chains in the enzyme chymotrypsin

1961 • 18 citations

The Acidic, Basic and α-Chymotrypsin-catalyzed Hydrolyses of Some Esters. A Kinetic Comparison¹

1955 • 15 citations

The Solvolysis of 1-Acetylimidazole in Concentrated Acid and Salt Solutions

1962 • 15 citations

DIRECT SPECTROPHOTOMETRIC EVIDENCE FOR AN ACYL-ENZYME INTERMEDIATE IN THE CHYMOTRYPSIN-CATALYZED HYDROLYSIS OF O-NITROPHENYL CINNAMATE¹

1959 • 14 citations

The effect of substituents on the hydrolysis of phenyl acetate by wheat germ lipase

1953 • 14 citations

THE INFLUENCE OF pH AND DEUTERIUM OXIDE ON THE KINETICS OF α-CHYMOTRYPSIN-CATALYZED REACTIONS^1,2

1961 • 12 citations

The Kinetics of the α-Chymotrypsin-catalyzed Hydrolysis of α-N-Carbethoxy-L-tyrosinamide and its Inhibition by α-N-Carbethoxy-D-tyrosinamide¹

1958 • 11 citations

The Dependence of the α-Chymotrypsin-catalyzed Hydrolysis of α-N-Nicotinyl-L-tyrosinhydrazide upon the Concentration of the Buffer¹

1958 • 9 citations

The effect of para-substitution on the rates of enzymic hydrolysis of phenyl acetates

1958 • 5 citations