Modulation of streptonigrin cytotoxicity by nitroxide sod mimics

DNA Damage and Oxygen Radical Toxicity

1988 • 1,964 citations

NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals.

1979 • 492 citations

Biologically active metal-independent superoxide dismutase mimics

1990 • 427 citations

Protection against tissue damage in vivo by desferrioxamine: What is its mechanism of action?

1989 • 385 citations

Superoxide dismutase: The first twenty years (1968–1988)

1988 • 375 citations

Oxoammonium cation intermediate in the nitroxide-catalyzed dismutation of superoxide.

1992 • 322 citations

Inhibition of oxygen-dependent radiation-induced damage by the nitroxide superoxide dismutase mimic, Tempol

1991 • 229 citations

A novel metal-free low molecular weight superoxide dismutase mimic.

1988 • 228 citations

Evidence for the involvement of N-ACETYL-p-quinoneimine in acetaminophen metabolism

1979 • 221 citations

Inhibition of Lipid Peroxidation by Spin Labels

1989 • 173 citations

Nitroxide stable radicals protect beating cardiomyocytes against oxidative damage.

1991 • 146 citations

Glutathione in Escherichia coli is dispensable for resistance to H2O2 and gamma radiation

1986 • 146 citations

In vivo localized ESR spectroscopy reflecting metabolism

1989 • 129 citations

Iron requirement in the bactericidal mechanism of streptonigrin

1982 • 121 citations

The mechanism of action of quinone antibiotics

1983 • 116 citations

Nitroxide Sod-Mimics: Modes of Action

1991 • 98 citations

Nitroxides block DNA scission and protect cells from oxidative damage

1991 • 94 citations

Reactions of the semiquinone free radicals of anti‐tumour agents with oxygen and iron complexes

1985 • 86 citations

Bacteria form intracellular free radicals in response to paraquat and streptonigrin. Demonstration of the potency of hydroxyl radical.

1987 • 80 citations

Identification of Nitroxide Radioprotectors

1992 • 76 citations

Iron enhances the bactericidal action of streptonigrin

1982 • 71 citations

The mechanism of pH-dependent hydrogen peroxide cytotoxicity in vitro

1988 • 71 citations

Mechanisms of hypoxic and aerobic cytotoxicity of mitomycin C in Chinese hamster V79 cells.

1991 • 70 citations

An electron paramagnetic resonance study of the interactions between the adriamycin semiquinone, hydrogen peroxide, iron-chelators, and radical scavengers

1991 • 64 citations

Cytotoxicity of commonly used nitroxide radical spin probes

1987 • 59 citations

Spin-label oximetry: kinetic study of cell respiration using a rapid-passage T1-sensitive electron spin resonance display.

1985 • 51 citations

Streptonigrin-induced deoxyribose degradation: Inhibition by superoxide dismutase, hydroxyl radical scavengers and iron chelators

1984 • 36 citations

Interactions of nitroxides with plasma and blood: Effect on 1/T₁ of water protons

1990 • 35 citations

Oximetry in cells and tissues using a nitroxide-liposome system

1989 • 29 citations

Desferal-Mn(III) in the therapy of diquat-induced cataract in rabbit

1991 • 25 citations

Potential of albumin labeled with nitroxides as a contrast agent for magnetic resonance imaging and spectroscopy

1990 • 24 citations

A mimic of superoxide dismutase activity protects Chlorella sorokiniana against the toxicity of sulfite

1989 • 24 citations

Reduction in tumor necrosis factor binding and cytotoxicity by hydrogen peroxide.

1990 • 22 citations

Streptonigrin toxicity in Escherichia coli: oxygen dependence and the role of the intracellular oxidation–reduction state

1982 • 17 citations

Sterically-Hindered Hydroxylamines as Bioactive Spin Labels

1990 • 16 citations

The evaluation of Escherichia coli as a model for oxidant stress in mammalian hepatocytes: Role of glutathione

1991 • 16 citations

Cytogenetic toxicity of paraquat and streptonigrin in Fanconi's anemia

1987 • 15 citations

Role of single-electron reduction potential in inhibition of reverse transcriptase by streptonigrin and sakyomicin A.

1987 • 7 citations