Genes Influencing Variation in Serum Osteocalcin Concentrations Are Linked to Markers on Chromosomes 16q and 20q1

New biochemical marker for bone metabolism. Measurement by radioimmunoassay of bone GLA protein in the plasma of normal subjects and patients with bone disease.

1980 • 658 citations

Contribution of trans-acting factor alleles to normal physiological variability: vitamin D receptor gene polymorphism and circulating osteocalcin.

1992 • 604 citations

Association of bone mineral density with polymorphism of the estrogen receptor gene

1996 • 567 citations

Extensions to multivariate normal models for pedigree analysis

1982 • 517 citations

Extensions to pedigree analysis III. Variance components by the scoring method

1976 • 438 citations

Cartilage-derived morphogenetic proteins. New members of the transforming growth factor-beta superfamily predominantly expressed in long bones during human embryonic development.

1994 • 415 citations

A human chondrodysplasia due to a mutation in a TGF-β superfamily member

1996 • 412 citations

Genetic and Environmental Contributions to Cardiovascular Risk Factors in Mexican Americans

1996 • 373 citations

Disruption of human limb morphogenesis by a dominant negative mutation in CDMP1

1997 • 359 citations

Osteocalcin. Biochemical considerations and clinical applications

1988 • 328 citations

Genetic determinants of bone mineral content at the spine and radius: A twin study

1987 • 324 citations

Rapid Bone Loss Is Associated with Increased Levels of Biochemical Markers

1998 • 248 citations

Genetic Factors in Bone Turnover*

1991 • 240 citations

A sequence variation: 713-8delC in the transforming growth factor-beta 1 gene has higher prevalence in osteoporotic women than in normal women and is associated with very low bone mass in osteoporotic women and increased bone turnover in both osteoporotic and normal women

1997 • 222 citations

Multipoint interval mapping of quantitative trait loci, using sib pairs.

1995 • 208 citations

Vitamin D receptor gene polymorphisms do not predict bone turnover and bone mass in healthy premenopausal women

1995 • 197 citations

Bone Mass Is Low in Relatives of Osteoporotic Patients

1988 • 195 citations

Osteocalcin induces chemotaxis, secretion of matrix proteins, and calcium-mediated intracellular signaling in human osteoclast-like cells.

1994 • 181 citations

Vitamin D receptor gene polymorphisms are not related to bone turnover, rate of bone loss, and bone mass in postmenopausal women: The OFELY study

1996 • 166 citations

Nonassociation of Estrogen Receptor Genotypes with Bone Mineral Density and Estrogen Responsiveness to Hormone Replacement Therapy in Korean Postmenopausal Women

1997 • 163 citations

A role for osteocalcin in osteoclast differentiation

1991 • 148 citations

Genetic influence on bone turnover in postmenopausal twins.

1996 • 136 citations

Collagen Iα1 Sp1 Polymorphism, Bone Mass, and Bone Turnover in Healthy French Premenopausal Women: The OFELY Study

1998 • 122 citations

Bone mineral, serum calcium, and dietary intakes of mother/daughter pairs

1986 • 81 citations

CHROMOSOMAL LOCALIZATION OF THE HUMAN OSTEOCALCIN GENE

1989 • 78 citations

Vitamin D Receptor Polymorphisms, Bone Mineral Density, and Bone Metabolism in Postmenopausal Mexican–American Women

1997 • 66 citations

Bone mineral density and bone markers in relation to vitamin D receptor gene polymorphisms in chinese men and women

1996 • 54 citations

Osteocalcin: Genetic and Physical Mapping of the Human Gene BGLAP and Its Potential Role in Postmenopausal Osteoporosis

1999 • 48 citations

Statistically robust approaches for sib‐pair linkage analysis

1998 • 21 citations

An enzyme immunoassay for intact, newly synthesized osteocalcin: A marker of bone formation

1995 • 4 citations

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