Blood-Brain and CSF Barriers to Penicillin and Related Organic Acids

A PHOTOMETRIC ADAPTATION OF THE SOMOGYI METHOD FOR THE DETERMINATION OF GLUCOSE

1944 • 10,350 citations

THE RENAL CLEARANCES OF SUBSTITUTED HIPPURIC ACID DERIVATIVES AND OTHER AROMATIC ACIDS IN DOG AND MAN 1

1945 • 1,598 citations

The concept of carrier transport and its corollaries in pharmacology.

1961 • 541 citations

Facilitated transfer of glucose from blood into brain tissue.

1965 • 441 citations

Active transport of Diodrast and phenolsulfonphthalein from cerebrospinal fluid to blood

1961 • 301 citations

Protein Metabolism of The Nervous System

1964 • 275 citations

Passage of drugs across body membranes.

1962 • 262 citations

THE ULTRAFILTRABLE CALCIUM OF HUMAN SERUM. I. ULTRAFILTRATION METHODS AND NORMAL VALUES 1

1957 • 252 citations

Renal tubular mechanisms for excretion of organic acids and bases

1964 • 241 citations

Potassium exchange between cerebrospinal fluid, plasma, and brain

1965 • 208 citations

‘Benemid,’ p-(di-n-Propylsulfamyl)-Benzoic Acid: Its Renal Affinity and Its Elimination

1951 • 161 citations

Mechanisms of Drug Absorption and Excretion Passage of Drugs in and out of the Central Nervous System

1962 • 147 citations

Exchange of Albumin Between Plasma and Lymph

1951 • 138 citations

Carrier transport of glucose between blood and cerebrospinal fluid

1964 • 137 citations

Clinical and Bacteriologic Studies of the Effect of Massive Doses of Penicillin G on Infections Caused by Gram-Negative Bacilli

1964 • 133 citations

The Relation of Protein Binding to the Pharmacology and Antibacterial Activity of Penicillins X, G, Dihydro F, and K

1947 • 108 citations

The physiological disposition of probenecid, including renal clearance, in man, studied by an improved method for its estimation in biological material.

1963 • 98 citations

Cerebral toxicity associated with massive intravenous penicillin therapy

1965 • 86 citations

Distribution of drugs between blood and cerebrospinal fluid: general methodology and effect of pH gradients.

1959 • 85 citations

Mechanisms of renal tubular transport

1958 • 73 citations

EFFECT OF ACETATE ON THE RENAL EXCRETION OF P-AMINOHIPPURATE IN THE DOG

1950 • 65 citations

Exchange of Albumin Between Plasma and Cerebrospinal Fluid

1953 • 59 citations

EFFECT OF SERUM BINDING ON THE DISTRIBUTION OF PENICILLINS IN THE RABBIT.

1965 • 59 citations

FACTORS INFLUENCING THE EXCHANGE OF SODIUM BETWEEN PLASMA AND CEREBROSPINAL FLUID*†

1959 • 54 citations

Exchange of Cerebrospinal Fluid Potassium With Blood and Brain

1965 • 52 citations

Influence of various drugs on the transport of ¹³¹I and PAH across the cerebrospinal‐fluid—blood barrier

1963 • 50 citations

INHIBITORS OF PENICILLIN BINDING TO SERUM PROTEINS.

1965 • 50 citations

Rapid efflux of some quaternary ammonium compounds from cerebrospinal fluid

1962 • 48 citations

Factors affecting distribution of iodide in brain and cerebrospinal fluid

1965 • 45 citations

STUDIES OF THE BLOOD-CEREBROSPINAL FLUID BARRIER TO CORTISOL IN THE DOG*

1961 • 41 citations

Clinical Aspects of the Blood-Brain Barrier

1964 • 40 citations

Passage of lipid-insoluble substances from cerebrospinal fluid to blood.

1962 • 39 citations

STUDIES ON THE PATHOGENESIS OF MENINGITIS. IV. PENICILLIN LEVELS IN THE CEREBROSPINAL FLUID IN EXPERIMENTAL MENINGITIS.

1964 • 38 citations

THE ABSORPTION INTO AND DISTRIBUTION OF PENICILLIN IN THE CEREBROSPINAL FLUID

1946 • 33 citations

A Study of Intrathecal Chemotherapy In Bacterial Meningitis

1953 • 30 citations

THE CONCENTRATIONS OF PENICILLINS IN THE CEREBROSPINAL FLUID AND BRAIN OF RABBITS WITH EXPERIMENTAL MENINGITIS

1965 • 29 citations

THE TRANSPORT AND EXCRETION OF URIC ACID IN MAN. I. TRUE URIC ACID IN NORMAL CEREBROSPINAL FLUID, IN PLASMA, AND IN ULTRAFILTRATES OF PLASMA

1947 • 27 citations

Benemid, p-(DI-n-propylsulfamyl)-benzoic acid; toxicologic properties.

1951 • 21 citations

Penicillin in neurology.

1948 • 15 citations

EPILEPTOGENIC EFFECTS OF PENICILLIN

1947 • 13 citations

Spinal fluid iodide transport in the dog

1964 • 12 citations