Regulation of Estrogen Receptor-mediated Long Range Transcription via Evolutionarily Conserved Distal Response Elements

Capturing Chromosome Conformation

2002 • 3,550 citations

Mechanisms of Estrogen Action

2001 • 1,945 citations

Estrogen Receptors: How Do They Signal and What Are Their Targets

2007 • 1,714 citations

Cofactor Dynamics and Sufficiency in Estrogen Receptor–Regulated Transcription

2000 • 1,658 citations

Estrogen Receptor-α Directs Ordered, Cyclical, and Combinatorial Recruitment of Cofactors on a Natural Target Promoter

2003 • 1,422 citations

Genome-wide analysis of estrogen receptor binding sites

2006 • 1,344 citations

Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture–on-chip (4C)

2006 • 1,336 citations

Chromosome-Wide Mapping of Estrogen Receptor Binding Reveals Long-Range Regulation Requiring the Forkhead Protein FoxA1

2005 • 1,328 citations

Chromosome Conformation Capture Carbon Copy (5C): A massively parallel solution for mapping interactions between genomic elements

2006 • 1,176 citations

Estrogen receptor interaction with estrogen response elements

2001 • 1,031 citations

Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions

2006 • 942 citations

Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line

1982 • 727 citations

Quantitative analysis of chromosome conformation capture assays (3C-qPCR)

2007 • 679 citations

A Hierarchical Network of Transcription Factors Governs Androgen Receptor-Dependent Prostate Cancer Growth

2007 • 666 citations

Covalent modifications of histones during development and disease pathogenesis

2007 • 634 citations

Proximity among Distant Regulatory Elements at the β-Globin Locus Requires GATA-1 and FOG-1

2005 • 492 citations

Whole-Genome Cartography of Estrogen Receptor α Binding Sites

2007 • 447 citations

Spatial and Temporal Recruitment of Androgen Receptor and Its Coactivators Involves Chromosomal Looping and Polymerase Tracking

2005 • 434 citations

Long-range intrachromosomal interactions in the T helper type 2 cytokine locus

2004 • 421 citations

Cross-regulation of histone modifications

2007 • 388 citations

The active spatial organization of the β-globin locus requires the transcription factor EKLF

2004 • 357 citations

Estrogen-responsive element of the human pS2 gene is an imperfectly palindromic sequence.

1989 • 330 citations

Methylation at arginine 17 of histone H3 is linked to gene activation

2002 • 319 citations

Sequence of the pS2 mRNA induced by estrogen in the human breast cancer cell line MCF-7

1984 • 304 citations

The 5′ flanking region of the pS2 gene contains a complex enhancer region responsive to oestrogens, epidermal growth factor, a tumour promoter (TPA), the c-Ha-ras oncoprotein and the c-jun protein.

1989 • 260 citations

Activation of Receptor Activator of NF-κB Ligand Gene Expression by 1,25-Dihydroxyvitamin D₃ Is Mediated through Multiple Long-Range Enhancers

2006 • 219 citations

Exchange of GATA Factors Mediates Transitions in Looped Chromatin Organization at a Developmentally Regulated Gene Locus

2008 • 213 citations

Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state

2007 • 208 citations

Identification of multiple, widely spaced estrogen-responsive regions in the rat progesterone receptor gene.

1994 • 191 citations

Enhancers Located within Two Introns of the Vitamin D Receptor Gene Mediate Transcriptional Autoregulation by 1,25-Dihydroxyvitamin D₃

2006 • 158 citations

A Global View of Transcriptional Regulation by Nuclear Receptors: Gene Expression, Factor Localization, and DNA Sequence Analysis

2008 • 122 citations

Oct4 dependence of chromatin structure within the extended Nanog locus in ES cells

2008 • 111 citations

Activation-dependent intrachromosomal interactions formed by the TNF gene promoter and two distal enhancers

2007 • 78 citations

A New Small Molecule Inhibitor of Estrogen Receptor α Binding to Estrogen Response Elements Blocks Estrogen-dependent Growth of Cancer Cells

2008 • 60 citations

Chromatin exposes intrinsic differences in the transcriptional activities of estrogen receptors alpha and beta

2003 • 48 citations