Cloning and expression of the Xenopus and mouse Msh2 DNA mismatch repair genes

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

1982 • 5,284 citations

CLUSTAL: a package for performing multiple sequence alignment on a microcomputer

1988 • 3,446 citations

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

1993 • 2,884 citations

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

1993 • 2,711 citations

Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

1994 • 2,071 citations

Mutation of a mutL Homolog in Hereditary Colon Cancer

1994 • 1,834 citations

PROTEIN-DNA RECOGNITION

1984 • 1,649 citations

A major developmental transition in early xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage

1982 • 1,635 citations

Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer

1994 • 1,544 citations

Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: An updated review

1993 • 1,076 citations

Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

1993 • 1,076 citations

Hypermutability and mismatch repair deficiency in RER+ tumor cells

1993 • 1,042 citations

[12] Unidirectional digestion with exonuclease III in DNA sequence analysis

1987 • 898 citations

MECHANISMS AND BIOLOGICAL EFFECTS OF MISMATCH REPAIR

1991 • 876 citations

Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history.

1993 • 796 citations

Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome.

1993 • 596 citations

An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.

1993 • 445 citations

Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer.

1993 • 443 citations

Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines.

1990 • 408 citations

The mRNA encoding elongation factor 1-α (EF-1α) is a major transcript at the midblastula transition in Xenopus

1989 • 395 citations

hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds.

1994 • 366 citations

Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage

1993 • 361 citations

The current status and portability of our sequence handling software

1986 • 357 citations

Heteroduplex repair in extracts of human HeLa cells

1991 • 355 citations

Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions.

1992 • 353 citations

[7] Random cloning and sequencing by the M13/dideoxynucleotide chain termination method

1987 • 292 citations

Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene.

1994 • 222 citations

Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins.

1992 • 221 citations

MEIOTIC GENE CONVERSION MUTANTS IN SACCHAROMYCES CEREVISIAE. I. ISOLATION AND CHARACTERIZATION OF pms1-1 AND pms1-2

1985 • 220 citations

Isolation and partial characterization of human cell mutants differing in sensitivity to killing and mutation by methylnitrosourea and N-methyl-N'-nitro-N-nitrosoguanidine.

1986 • 203 citations

Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: homology of PMS1 to procaryotic MutL and HexB

1989 • 193 citations

Self-destruction and tolerance in resistance of mammalian cells to alkylation damage

1992 • 173 citations

Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene

1989 • 148 citations

The yeast gene MSH3 defines a new class of eukaryotic MutS homologues

1993 • 140 citations

Dual bidirectional promoters at the mouse dhfr locus: cloning and characterization of two mRNA classes of the divergently transcribed Rep-1 gene.

1989 • 128 citations

Superfamily of UvrA-related NTP-binding proteins

1990 • 125 citations

Mismatch recognition in chromosomal interactions and speciation

1993 • 84 citations

Nucleotide sequence of the Salmonella typhimurium mutS gene required for mismatch repair: homology of MutS and HexA of Streptococcus pneumoniae

1988 • 83 citations

Nucleotide sequence of the hexA gene for DNA mismatch repair in Streptococcus pneumoniae and homology of hexA to mutS of Escherichia coli and Salmonella typhimurium

1988 • 75 citations

DNA mismatch repair in Xenopus egg extracts: repair efficiency and DNA repair synthesis for all single base-pair mismatches.

1990 • 65 citations

Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene

1994 • 54 citations

Theswi4⁺gene ofSchizosaccharomyces pombeencodes a homologue of mismatch repair enzymes

1992 • 52 citations

Mismatch repair involving localized DNA synthesis in extracts of Xenopus eggs.

1989 • 34 citations

Characterization of a DNA mismatch-binding activity in yeast extracts.

1993 • 34 citations

The Escherichia coli fdv gene probably encodes mutS and is located at minute 58.8 adjacent to the hyc-hyp gene cluster

1991 • 19 citations

Azotobacter vinelandii mutS: nucleotide sequence and mutant analysis

1993 • 13 citations

The sequence of a 6·3 kb segment of yeast chromosome III reveals an open reading frame coding for a putative mismatch binding protein

1991 • 9 citations

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