Receptor-bound somatostatin and epidermal growth factor are processed differently in GH4C1 rat pituitary cells.

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.

1976 • 1,293 citations

pH and the recycling of transferrin during receptor-mediated endocytosis.

1983 • 1,165 citations

Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.

1980 • 798 citations

Rapid acidification of endocytic vesicles containing α2-macroglobulin

1982 • 672 citations

Somatostatin

1983 • 581 citations

Receptor-Mediated Endocytosis of Hormones in Cultured Cells

1981 • 388 citations

Direct demonstration that receptor crosslinking or aggregation is important in insulin action

1978 • 388 citations

Biological role of epidermal growth factor-receptor clustering. Investigation with monoclonal anti-receptor antibodies.

1983 • 327 citations

[46] Clonal strains of hormone-producing pituitary cells

1979 • 296 citations

Characterization of functional receptors for somatostatin in rat pituitary cells in culture.

1978 • 290 citations

Epidermal growth factor and thyrotropin-releasing hormone act similarly on a clonal pituitary cell strain. Modulation of hormone production and inhibition of cell proliferation

1980 • 226 citations

Insulin Metabolism and Degradation*

1981 • 197 citations

Monoclonal antibodies against receptor for epidermal growth factor induce early and delayed effects of epidermal growth factor.

1981 • 191 citations

Desensitization of the beta-adrenergic receptor of frog erythrocytes. Recovery and characterization of the down-regulated receptors in sequestered vesicles.

1983 • 191 citations

Pertussis toxin blocks both cyclic AMP-mediated and cyclic AMP-independent actions of somatostatin. Evidence for coupling of Ni to decreases in intracellular free calcium.

1985 • 190 citations

Binding and receptor-mediated degradation of insulin in adipocytes

1978 • 180 citations

The asialoglycoprotein receptor internalizes and recycles independently of the transferrin and insulin receptors

1983 • 161 citations

Down-regulation of opiate receptor in neuroblastoma x glioma NG108-15 hybrid cells. Chloroquine promotes accumulation of tritiated enkephalin in the lysosomes.

1984 • 139 citations

The Somatostatin Receptor Is Directly Coupled to Adenylate Cyclase in GH4Ci Pituitary Cell Membranes*

1984 • 130 citations

Characterization of bombesin receptors in a rat pituitary cell line.

1983 • 129 citations

Somatostatin Inhibits Basal and Vasoactive Intestinal Peptide-Stimulated Hormone Release by Different Mechanisms in GH Pituitary Cells^*

1983 • 101 citations

Somatostatin Inhibits Vasoactive Intestinal Peptide-Stimulated Cyclic Adenosine Monophosphate Accumulation in GH Pituitary Cells^*

1983 • 93 citations

Intracellular receptor for somatostatin in gastric mucosal cells: decomposition and reconstitution of somatostatin-stimulated phosphoprotein phosphatases.

1982 • 93 citations

Somatostatin lowers the cytosolic free Ca2+ concentration in clonal rat pituitary cells (GH3 cells)

1984 • 81 citations

PURIFICATION OF PEPTIDES: AN EFFICIENT PROCEDURE FOR THE SEPARATION OF PEPTIDES FROM AMINO ACIDS AND SALT

1980 • 73 citations

Interactions Between Insulin and Its Receptors After the Initial Binding Event: Functional Heterogeneity and Relationships to Insulin Degradation

1979 • 66 citations

Somatostatin Analogs: Correlation between Receptor Binding Affinity and Biological Potency in GH PituitaryCells^*

1983 • 66 citations

Evidence for an intracellular somatostatin receptor in pancreas: A comparative study with reference to gastric mucosa

1982 • 60 citations

Differences in the Rates of Internalization of¹²⁵I-Labeled Human Chorionic Gonadotropin, Luteinizing Hormone, and Epidermal Growth Factor by Ovine Luteal Cells^*

1983 • 55 citations

Rapid temperature-dependent transformation of the thyrotropin-releasing hormone-receptor complex in rat pituitary tumor cells.

1982 • 55 citations

Characterization of the association of tritiated enkephalin with neuroblastoma cells under conditions optimal for receptor down regulation.

1983 • 51 citations

Receptor mediated endocytosis of polypeptide hormones: Mechanism and significance

1982 • 51 citations

Receptor-Mediated Endocytosis

2016 • 47 citations

The mechanism of receptor-mediated degradation of insulin in isolated rat adipocytes: Indirect evidence for a non-lysosomal pathway

1983 • 25 citations

Receptors, acceptors, and the action of polypeptide hormones: illustrative studies with epidermal growth factor (urogastrone)

1983 • 20 citations

Mechanisms of Somatostatin Action in Pituitary Cells

1985 • 17 citations

Binding, membrane redistribution, internalization and lysosomal association of [125I]anti-insulin receptor antibody in IM-9-cultured human lymphocyte

1981 • 16 citations

Peptide-Degrading Enzymatic Activities in GH₃Cells and Rat Anterior Pituitary Homogenates^*

1984 • 14 citations

Binding and internalization of epidermal growth factor by rat pituitary tumor cells

1983 • 12 citations

Binding and degradation of 125I-labeled insulin by a clonal line of rat pituitary tumor cells

1983 • 9 citations