Structural comparison of apomyoglobin and metaquomyoglobin: pH titration of histidines by NMR spectroscopy

Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins

1983 • 3,150 citations

Coherence transfer by isotropic mixing: Application to proton correlation spectroscopy

1983 • 2,638 citations

Improved spectral resolution in COSY 1H NMR spectra of proteins via double quantum filtering

1983 • 2,327 citations

A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules

1980 • 1,886 citations

Selection of coherence-transfer pathways in NMR pulse experiments

1984 • 1,070 citations

Specific Intermediates in the Folding Reactions of Small Proteins and the Mechanism of Protein Folding

1982 • 1,041 citations

Experimental and Theoretical Aspects of Protein Folding

1975 • 965 citations

¹H‐nmr parameters of the common amino acid residues measured in aqueous solutions of the linear tetrapeptides H‐Gly‐Gly‐X‐<scp>L</scp>‐Ala‐OH

1979 • 750 citations

Iterative schemes for bilinear operators; application to spin decoupling

1988 • 724 citations

Structural Characterization of a Partly Folded Apomyoglobin Intermediate

1990 • 708 citations

Structure of myoglobin refined at 2·0 Å resolution

1977 • 676 citations

Acid-induced folding of proteins.

1990 • 555 citations

Determinants of a protein fold

1987 • 498 citations

Characterization of a partly folded protein by NMR methods: studies on the molten globule state of guinea pig .alpha.-lactalbumin

1989 • 473 citations

Observation of histidine residues in proteins by nuclear magnetic resonance spectroscopy

1975 • 416 citations

Analysis of networks of coupled spins by multiple quantum N.M.R.

1983 • 381 citations

Improved techniques for homonuclear rotating-frame and isotropic mixing experiments

1987 • 335 citations

Fourier transform multiple quantum nuclear magnetic resonance

1978 • 329 citations

Origin of τ2 and τ2 ridges in 2D NMR spectra and procedures for suppression

1986 • 321 citations

Polymer Principles in Protein Structure and Stability

1991 • 308 citations

Thermodynamic study of the apomyoglobin structure

1988 • 299 citations

Motions in Proteins

1979 • 281 citations

High-resolution study of the three-dimensional structure of horse heart metmyoglobin

1990 • 278 citations

Intermediates in Protein Folding Reactions and the Mechanism of Protein Folding

1975 • 257 citations

Reversible Conformational Changes of Myoglobin and Apomyoglobin

1965 • 255 citations

Determination of the tautomeric form of the imidazole ring of L-histidine in basic solution by carbon-13 magnetic resonance spectroscopy

1973 • 214 citations

Relative Conformations of Sperm Whale Metmyoglobin and Apomyoglobin in Solution

1965 • 190 citations

Reaction of myoglobin with phenylhydrazine: a molecular doorstop

1984 • 190 citations

Probing the stability of a partly folded apomyoglobin intermediate by site-directed mutagenesis

1991 • 179 citations

Neutron diffraction study of carbonmonoxymyoglobin

1991 • 158 citations

Phase diagram for acidic conformational states of apomyoglobin

1990 • 156 citations

Protein stability: electrostatics and compact denatured states.

1991 • 151 citations

Changes in Side Chain Reactivity Accompanying the Binding of Heme to Sperm Whale Apomyoglobin

1964 • 130 citations

Use of site-directed mutagenesis to destabilize native apomyoglobin relative to folding intermediates

1989 • 124 citations

Influence of Prosthetic Groups on Protein Folding and Subunit Assembly

1972 • 118 citations

Side-chain clusters in protein structures and their role in protein folding

1991 • 107 citations

The transition between ‘acid’ and ‘alkaline’ ferric heme proteins

1968 • 100 citations

Electrostatic stabilization in myoglobin. The pH dependence of summed electrostatic contributions

1979 • 94 citations

Unfolding pathway of myoglobin: Molecular properties of intermediate forms

1986 • 91 citations

Carboxymethylation of Sperm Whale Metmyoglobin

1963 • 87 citations

Assignment of resonances in the 1H nuclear magnetic resonance spectrum of the carbon monoxide complex of sperm whale myoglobin by phase-sensitive two-dimensional techniques

1987 • 84 citations

A comparison of the conformation of sperm whale metmyoglobin with that of apomyoglobin

1965 • 83 citations

Analysis of 1H NMR spectra of proteins using multiple-quantum coherence

1986 • 77 citations

Fluorescence studies of Aplysia and sperm whale apomyoglobins

1970 • 75 citations

Elimination of baseline distortions and minimization of artifacts from phased 2D NMR spectra

1989 • 69 citations

Characterization of hydrophobic cores in apomyoglobin: a proton NMR spectroscopy study

1990 • 68 citations

Effect of heme binding on the structure and stability of Escherichia coli apocytochrome b562

1991 • 62 citations

Proton nuclear magnetic resonance study of histidine ionizations in myoglobins of various species. Comparison of observed and computed pK values

1978 • 61 citations

Unfolding pathway of myoglobin. Evidence for a multistate process

1983 • 56 citations

Contribution of histidine residues to the conformational stability of ribonuclease T1 and mutant Glu-58 .fwdarw. Ala

1990 • 55 citations

Electrostatic effects in myoglobin. Application of the modified Tanford-Kirkwood theory to myoglobins from horse, California grey whale, harbor seal, and California sea lion

1975 • 52 citations

Proton nuclear magnetic resonance study of histidine ionizations in myoglobins of various species. Specific assignment of individual resonances

1978 • 46 citations

Electrostatic stabilization in myoglobin. Interactive free energies between individual sites

1979 • 45 citations

Similarities in structure between holocytochrome b5 and apocytochrome b5: NMR studies of the histidine residues

1991 • 44 citations

Assignment of proton NMR resonances of histidine and other aromatic residues in met-, cyano-, oxy-, and (carbon monoxy)myoglobins

1984 • 41 citations

Carboxymethylation of Sperm Whale Myoglobin in the Crystalline State

1970 • 39 citations

Titration behavior and tautomeric states of individual histidine residues of myoglobins. Application of natural abundance carbon 13 nuclear magnetic resonance spectroscopy.

1977 • 39 citations

Helix formation in apocytochrome b5: the role of a neutral histidine at the N-cap position

1991 • 36 citations

Structural properties of apocytochrome b5: presence of a stable native core

1990 • 36 citations

Carboxymethylation of Sperm Whale Myoglobin in the Dissolved State

1970 • 35 citations

Electrostatic interactions in sperm whale myoglobin. Site specificity, roles in structural elements, and external electrostatic potential distributions.

1985 • 33 citations

Charge-site communication in proteins: electrostatic heme linkage of azide binding by sperm whale myoglobin

1980 • 27 citations

Proton and nitrogen-15 NMR resonance assignments and preliminary structural characterization of Escherichia coli apocytochrome b562

1991 • 27 citations

Structural features of the protoporphyrin-apomyoglobin complex: a proton NMR spectroscopy study

1990 • 23 citations

Electrostatic stabilization in sperm whale and harbor seal myoglobins. Identification of groups primarily responsible for changes in anchoring of the A helix

1980 • 20 citations

Structure-Volume Relationships of Proteins

1973 • 18 citations

Molecular association behavior of apomyoglobin I from the seal (Phoca vitulina)

1962 • 15 citations

Variations of electrostatic interactions in myoglobin probed by UVRR spectroscopy. Effect of iron ligand and pH on tryptophan and tyrosine vibrations

1991 • 6 citations