The effect of interleukin-1 on cytokine gene expression in cultured human articular chondrocytes analyzed by messenger rna phenotyping

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities.

1987 • 1,345 citations

Interleukin-1 and Its Biologically Related Cytokines

1989 • 1,180 citations

Wound Macrophages Express TGF-α and Other Growth Factors in Vivo: Analysis by mRNA Phenotyping

1988 • 1,107 citations

Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis

1990 • 963 citations

Excessive production of interleukin 6/B cell stimulatory factor‐2 in rheumatoid arthritis

1988 • 793 citations

Endothelial Cell Gene Expression of a Neutrophil Chemotactic Factor by TNF-α, LPS, and IL-1β

1989 • 785 citations

Quantitative analysis of cytokine gene expression in rheumatoid arthritis.

1990 • 610 citations

Interleukin 1 induces interleukin 1. I. Induction of circulating interleukin 1 in rabbits in vivo and in human mononuclear cells in vitro.

1987 • 545 citations

Multiple actions of interleukin 6 within a cytokine network

1988 • 536 citations

Recombinant human TNF induces production of granulocyte–monocyte colony-stimulating factor

1986 • 528 citations

Genomic structure of the human monocyte-derived neutrophil chemotactic factor IL-8.

1989 • 515 citations

Isolation of an interleukin‐1‐like factor from human joint effusions

1983 • 450 citations

Production of interleukin-8 by human dermal fibroblasts and keratinocytes in response to interleukin-1 or tumour necrosis factor.

1989 • 422 citations

Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1 alpha.

1988 • 335 citations

Genes for extracellular-matrix-degrading metalloproteinases and their inhibitor, TIMP, are expressed during early mammalian development.

1989 • 284 citations

Message amplification phenotyping (MAPPing): a technique to simultaneously measure multiple mRNAs from small numbers of cells.

1989 • 281 citations

Interleukin 1 induces interleukin 1. II. Recombinant human interleukin 1 induces interleukin 1 production by adult human vascular endothelial cells.

1987 • 279 citations

Cytokines in chronic inflammatory arthritis. II. Granulocyte-macrophage colony-stimulating factor in rheumatoid synovial effusions.

1989 • 265 citations

Enhanced production of neutrophil-activating peptide-1/interleukin-8 in rheumatoid arthritis.

1991 • 256 citations

Cytokines in chronic inflammatory arthritis. I. Failure to detect T cell lymphokines (interleukin 2 and interleukin 3) and presence of macrophage colony-stimulating factor (CSF-1) and a novel mast cell growth factor in rheumatoid synovitis.

1988 • 249 citations

Tumour necrosis factor in synovial exudates.

1988 • 242 citations

Human interleukin 1 induces interleukin 1 gene expression in human vascular smooth muscle cells.

1987 • 223 citations

Effects of human recombinant CSF-GM and highly purified CSF-1 on the formation of multinucleated cells with osteoclast characteristics in long-term bone marrow cultures

1986 • 215 citations

Cytokine production in the rheumatoid joint: implications for treatment.

1990 • 144 citations

Expression of IL-1 genes in human and bovine chondrocytes: A mechanism for autocrine control of cartilage matrix degradation

1986 • 113 citations

Cytokine expression in rheumatoid arthritis.

1991 • 94 citations

Interleukin 1 preferentially stimulates the production of tissue-type plasminogen activator by human articular chondrocytes

1987 • 63 citations

Constitutive production of interleukin 6/B cell stimulatory factor-2 from inflammatory synovium

1989 • 52 citations

Interleukin 1 and tumor necrosis factor‐α additively increase the levels of granulocyte‐macrophage and granulocyte colony‐stimulating factor (CSF) mRNA in human fibroblasts

1989 • 46 citations

Recombinant human granulocyte‐macrophage colony‐stimulating factor induces secretion of autoinhibitory monokines by U‐937 cells

1988 • 42 citations

Interleukin‐1 induces interleukin‐1α and interleukin‐1β gene expression in synovial fibroblasts and peripheral blood monocytes

1989 • 40 citations

Independent induction of interleukin 6 and prostaglandin E2 by interleukin 1 in human articular chondrocytes

1990 • 37 citations

Characterization of granulocyte chemotactic activity from human cytokine-stimulated chondrocytes as interleukin 8

1990 • 37 citations

Retinoids and synovial factor(s) stimulate the production of plasminogen activator by cultured human chondrocytes. A possible role for plasminogen activator in the resorption of cartilage in vitro

1985 • 31 citations

Expression of the genes of interferons and other cytokines in normal and diseased tissues of man

1989 • 22 citations

Kinetics of interleukin 2 mRNA and protein produced in the human T-cell line Jurkat and the effect of cyclosporin A

1989 • 12 citations