Age-dependent changes in beta-adrenergic receptor subtypes and adenylyl cyclase activation in adipocytes from Fischer 344 rats.

Metabolism of Isolated Fat Cells

1964 • 4,431 citations

Methods for the determination of adipose cell size in man and animals

1968 • 896 citations

Cloning, Sequencing, and Expression of the Gene Coding for the Human Platelet α ₂ -Adrenergic Receptor

1987 • 792 citations

Atypical β-adrenoceptor on brown adipocytes as target for anti-obesity drugs

1984 • 724 citations

Antibodies directed against synthetic peptides distinguish between GTP-binding proteins in neutrophil and brain.

1987 • 356 citations

An adipose tissue-specific beta-adrenergic receptor. Molecular cloning and down-regulation in obesity.

1991 • 291 citations

Molecular characterization of the mouse beta 3-adrenergic receptor: relationship with the atypical receptor of adipocytes.

1991 • 277 citations

Adenosine analogs inhibit adipocyte adenylate cyclase by a GTP-dependent process: basis for actions of adenosine and methylxanthines on cyclic AMP production and lipolysis.

1978 • 253 citations

Heterogeneous distribution of beta and alpha‐2 adrenoceptor binding sites in human fat cells from various fat deposits: functional consequences

1987 • 241 citations

Coexistence of three β-adrenoceptor subtypes in white fat cells of various mammalian species

1991 • 203 citations

The fat cell adenylate cyclase system. Characterization and manipulation of its bimodal regulation by GTP.

1979 • 171 citations

Two classes of cAMP analogs which are selective for the two different cAMP-binding sites of type II protein kinase demonstrate synergism when added together to intact adipocytes.

1984 • 147 citations

Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells

1971 • 144 citations

Catecholamine-induced lipolysis in adipose tissue of the elderly.

1990 • 131 citations

Diet and the Suitability of the Male Fischer 344 Rat as a Model for Aging Research

1993 • 117 citations

Differential adrenergic regulation of beta 1- and beta 3-adrenoreceptor messenger ribonucleic acids in adipose tissues.

1992 • 98 citations

β‐Adrenergic Receptors and Catecholamine‐Sensitive Adenylate Cyclase in Rat Fat‐Cell Membranes: Influence of Growth, Cell Size and Aging

1978 • 98 citations

Activation of the particulate low Km phosphodiesterase of adipocytes by addition of cAMP-dependent protein kinase.

1988 • 78 citations

Effects of age and cell size on rat adipose tissue metabolism.

1975 • 77 citations

Influence of age on size and number of fat cells in the epididymal depot

1975 • 74 citations

Inhibition of lipolysis by adenosine is potentiated with age.

1984 • 65 citations

Transfection of human 5-hydroxytryptamine1A receptors in NIH-3T3 fibroblasts: effects of increasing receptor density on the coupling of 5-hydroxytryptamine1A receptors to adenylyl cyclase.

1992 • 63 citations

Multiple beta adrenergic receptor subclasses mediate the l-isoproterenol-induced lipolytic response in rat adipocytes.

1992 • 57 citations

Hormone-sensitive fat cell adenylate cyclase in the rat. Influences of growth, cell size, and aging.

1976 • 57 citations

Alterations in mRNA levels, expression, and function of GTP-binding regulatory proteins in adipocytes from obese mice (C57BL/6J-ob/ob)

1991 • 53 citations

Effect of aging on the adenyl cyclase and phosphodiesterase activity of isolated fat cells of rat

1970 • 49 citations

Characterization and Use of Crude α-Subunit Preparations for Quantitative Immunoblotting of G Proteins

1994 • 48 citations

Relationship between lipolysis and cyclic AMP generation mediated by atypical β‐adrenoceptors in rat adipocytes

1991 • 44 citations

Age-Associated Decrease in Beta-Adrenergic Receptors and Adenylate Cyclase Activity in Rat Brown Adipose Tissue

1988 • 41 citations

Increased alpha 2-adrenergic binding sites and antilipolytic effect in adipocytes from genetically obese rats.

1990 • 37 citations

Action of Food Restriction on Age-related Changes in Adipocyte Lipolysis

1987 • 25 citations

Drop in the "atypical" beta-adrenergic response and modification of the beta/alpha 2-adrenoceptor balance in fat cells from aging rabbits.

1992 • 23 citations

Release of small amounts of free fatty acids from human adipocytes as determined by chemiluminescence.

1993 • 18 citations

Non-adrenergic sites for imidazolines are not directly involved in the α2-adrenergic antilipolytic effect of UK 14304 in rat adipocytes

1990 • 18 citations

Evidence for altered expression of the GTP-dependent regulatory proteins, Gs and Gi, in adipocytes from aged rats

1989 • 17 citations

Age-Associated Differences in Beta Adrenergic-Stimulated Lipolysis in Adipocytes From Sprague-Dawley and Fischer 344 Rats

1991 • 7 citations