Cocaine euphoria, dysphoria, and tolerance assessed using drug-induced changes in brain-stimulation reward

Psychopharmacology: The third generation of progress

1988 • 3,403 citations

Cocaine and Other Stimulants

1988 • 982 citations

On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine

1977 • 733 citations

New concepts in cocaine addiction: The dopamine depletion hypothesis

1985 • 608 citations

Postcocaine anhedonia. An animal model of cocaine withdrawal.

1991 • 505 citations

Dopamine in the nucleus accumbens during cocaine self-administration as studied by in vivo microdialysis

1989 • 386 citations

Extracellular Concentrations of Cocaine and Dopamine Are Enhanced During Chronic Cocaine Administration

1990 • 321 citations

Changes in Mood, Craving, and Sleep During Short-term Abstinence Reported by Male Cocaine Addicts

1990 • 284 citations

Electrophysiological effects of cocaine in the mesoaccumbens dopamine system: repeated administration.

1989 • 273 citations

Acute Systemic Effects of Cocaine in Man: A Controlled Study by Intranasal and Intravenous Routes

1977 • 256 citations

Cocaine-induced place preference conditioning: Lack of effects of neuroleptics and 6-hydroxydopamine lesions

1982 • 241 citations

Persistence of neurochemical changes in dopamine systems after repeated cocaine administration.

1990 • 217 citations

Mesocorticolimbic Dopamine Systems and Reward

1988 • 207 citations

Discriminating between reward and performance: A critical review of intracranial self-stimulation methodology

1983 • 174 citations

Choice Behavior in Rhesus Monkeys: Cocaine Versus Food

1978 • 160 citations

Pimozide and amphetamine have opposing effects on the reward summation function

1984 • 156 citations

Acute tolerance to cocaine in humans

1988 • 124 citations

A10 somatodendritic dopamine autoreceptor sensitivity following withdrawal from repeated cocaine treatment

1990 • 122 citations

Selective alterations in cerebral metabolism within the mesocorticolimbic dopaminergic system produced by acute cocaine administration in rats

1988 • 116 citations

The Neuropharmacological Basis of Reward

1991 • 103 citations

Buprenorphine and naltrexone effects on cocaine self-administration by rhesus monkeys.

1990 • 103 citations

Postcocaine depression and sensitization of brain-stimulation reward: Analysis of reinforcement and performance effects

1990 • 97 citations

Cocaine: Acute effects of reinforcement thresholds for self-stimulation behavior to the medial forebrain bundle

1978 • 90 citations

Reward and detection thresholds for brain stimulation: dissociative effects of cocaine

1981 • 85 citations

Chronic cocaine and rat brain catecholamines: long-term reduction in hypothalamic and frontal cortex dopamine metabolism

1990 • 72 citations

Cocaine withdrawal produces behavioral disruptions in rats

1987 • 67 citations

Correlation of behavioral and neurochemical effects of acute administration of cocaine in rats

1978 • 65 citations

Bromocriptine produces decreases in cocaine self-administration in the rat.

1990 • 59 citations

Characteristics of tolerance, recovery from tolerance and cross-tolerance for cocaine used as a discriminative stimulus.

1986 • 58 citations

The effect of chronic cocaine on self-stimulation train-duration thresholds

1988 • 53 citations

Potentiation of cocaine's discriminative effects by caffeine: A time-effect analysis

1990 • 51 citations

Effect of chronic cocaine on dopamine synthesis in the nucleus accumbens as determined by microdialysis perfusion with NSD-1015

1990 • 41 citations

Evidence for cocaine dependence in monkeys following a prolonged period of exposure

1988 • 41 citations

Nimodipine inhibits cocaine-induced dopamine release and motor stimulation

1990 • 37 citations

Cocaine facilitates prefrontal cortex self-stimulation

1990 • 23 citations

An Overview of Assessing Drug Reinforcement

1987 • 20 citations

Bromocriptine antagonizes behavioral effects of cocaine in the rat

1989 • 17 citations

A systematic evaluation of the properties of self-stimulation train-duration response functions.

1987 • 14 citations

The interactive effects of cocaine and imipramine on self-stimulation train-duration thresholds

1988 • 14 citations

A systematic evaluation of the properties of self-stimulation train-duration response functions.

1987 • 13 citations

Chronic imipramine does not block cocaine-induced increases in brain stimulation reward

1989 • 10 citations

The effects of chronic cocaine administration on brain neurotransmitter receptors

1990 • 8 citations

Deleted Work

1955 • 0 citations