IFN-γ Enhances Osteoclast Generation in Cultures of Peripheral Blood from Osteopetrotic Patients and Normalizes Superoxide Production

Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo.

1990 • 827 citations

Actions of recombinant interleukin 1, interleukin 2, and interferon-gamma on bone resorption in vitro.

1986 • 484 citations

Abundant calcitonin receptors in isolated rat osteoclasts. Biochemical and autoradiographic characterization.

1986 • 456 citations

The human osteoclast precursor circulates in the monocyte fraction.

1996 • 347 citations

Leukocytes and Ischemia-Induced Myocardial Injury

1986 • 321 citations

Long-Term Treatment of Osteopetrosis with Recombinant Human Interferon Gamma

1995 • 268 citations

Partial Correction of the Phagocyte Defect in Patients with X-Linked Chronic Granulomatous Disease by Subcutaneous Interferon Gamma

1988 • 264 citations

Potentiation of osteoclast bone-resorption activity by inhibition of nitric oxide synthase.

1994 • 246 citations

Recombinant human interferon-gamma inhibits formation of human osteoclast-like cells.

1986 • 187 citations

Oxidant injury of lung parenchymal cells.

1981 • 185 citations

Role of cytokines in the regulation of bone resorption

1993 • 183 citations

Preparation and characterization of a mouse osteoclast-like multinucleated cell population

1992 • 159 citations

Preferential inhibition of cytokine-stimulated bone resorption by recombinant interferon gamma

1986 • 151 citations

Superoxide and bone resorption

1994 • 133 citations

The human osteoclast precursor circulates in the monocyte fraction

1996 • 128 citations

Osteoprotegerin and osteoprotegerin ligand effects on osteoclast formation from human peripheral blood mononuclear cell precursors

1999 • 122 citations

Oxygen derived free radicals in osteoclasts: The specificity and location of the nitroblue tetrazolium reaction

1990 • 118 citations

Recombinant human interferon gamma therapy for osteopetrosis

1992 • 116 citations

Human osteopetrosis

1980 • 112 citations

Interferon-gamma activates human neutrophil oxygen metabolism and exocytosis.

1988 • 106 citations

Human blood-mobilized hematopoietic precursors differentiate into osteoclasts in the absence of stromal cells.

1996 • 96 citations

Role of cytokines in bone resorption

1993 • 82 citations

Nitroblue tetrazolium reduction and bone resorption by osteoclasts in vitro inhibited by a manganese-based superoxide dismutase mimic

1992 • 73 citations

Activation of Murine Polymorphonuclear Neutrophils for Fungicidal Activity by Recombinant Gamma Interferon

1987 • 66 citations

Host Defense in Infantile Osteopetrosis

1979 • 62 citations

A New Method to Isolate Large Numbers of Rabbit Osteoclasts and Osteoclast-like Cells: Application to the Characterization of Serum Response Element Binding Proteins During Osteoclast Differentiation

1998 • 51 citations

Application of reflected light microscopy to identify and quantitate resorption by isolated osteoclasts

1991 • 41 citations

Osteopetrosis

1993 • 31 citations

Cultured circulating mononuclear cells from osteopetrotic infants express the osteoclast-associated vitronectin receptor and form multinucleated cells in response to 1,25-dihydroxyvitamin D3

1993 • 17 citations

Inhibitory effects ofγ-interferon on bradykinin-induced bone resorption and prostaglandin formation in cultured mouse calvarial bones

1991 • 5 citations