Mapping susceptibility genes for asthma and allergy

Association of Asthma with Serum IgE Levels and Skin-Test Reactivity to Allergens

1989 • 1,689 citations

Linkage Analysis of IL4 and Other Chromosome 5q31.1 Markers and Total Serum Immunoglobulin E Concentrations

1994 • 1,025 citations

Relation between Airway Responsiveness and Serum IgE in Children with Asthma and in Apparently Normal Children

1991 • 806 citations

A genome-wide search for quantitative trait loci underlying asthma

1996 • 797 citations

Genetic Susceptibility to Asthma — Bronchial Hyperresponsiveness Coinherited with a Major Gene for Atopy

1995 • 774 citations

The Association of Atopy with a Gain-of-Function Mutation in the α Subunit of the Interleukin-4 Receptor

1997 • 743 citations

A genome-wide search for asthma susceptibility loci in ethnically diverse populations

1997 • 712 citations

LINKAGE BETWEEN IMMUNOGLOBULIN E RESPONSES UNDERLYING ASTHMA AND RHINITIS AND CHROMOSOME 11q

1989 • 624 citations

Genome-wide search for asthma susceptibility loci in a founder population. The Collaborative Study on the Genetics of Asthma

1998 • 396 citations

Evidence for a Locus Regulating Total Serum IgE Levels Mapping to Chromosome 5

1994 • 395 citations

Bronchial hyperreactivity.

1980 • 378 citations

Allelic association of gene markers on chromosomes 5q and 11q with atopy and bronchial hyperresponsiveness.

1996 • 263 citations

DOES T4 TOXICOSIS EXIST ?

1975 • 252 citations

Investigation of an interleukin-4 promoter polymorphism for associations with asthma and atopy.

1996 • 250 citations

Linkage of Asthma and Total Serum IgE Concentration to Markers on Chromosome 12q: Evidence from Afro-Caribbean and Caucasian Populations

1996 • 226 citations

Genetics of Atopy and Asthma: The Rationale behind Promoter-based Candidate Gene Studies (IL-4 and IL-10)

1997 • 197 citations

Common Polymorphisms in the Coding Part of the IL4-Receptor Gene

1997 • 131 citations

The Predictive Relationship Between Serum IgE Levels at Birth and Subsequent Incidences of Lower Respiratory Illnesses and Eczema in Infants

1992 • 117 citations

The pathogenesis and significance of bronchial hyper-responsiveness in airways disease

1987 • 116 citations

Evidence for Linkage of Chromosome 12q15–q24.1 Markers to High Total Serum IgE Concentrations in Children of the German Multicenter Allergy Study

1997 • 113 citations

Relations of bronchial responsiveness to allergy skin test reactivity, lung function, respiratory symptoms, and diagnoses in thirteen-year-old New Zealand children

1995 • 101 citations

Linkage between atopy and the IgE high-affinity receptor gene at 11q13 in atopic dermatitis families

1998 • 82 citations

Characterization of Obstructive Airway Disease in Family Members of Probands with Asthma

1998 • 72 citations

Worldwide trends in asthma mortality.

1991 • 59 citations

CD28 functions as an adhesion molecule and is involved in the regulation of human IgE synthesis

1995 • 24 citations

The Genetics of Asthma

1996 • 15 citations

Regulation of IgE Synthesis

1984 • 15 citations