Appetitive Instrumental Learning Is Impaired by Inhibition of cAMP-Dependent Protein Kinase within the Nucleus Accumbens
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References (62)
The Rat Brain in Stereotaxic Coordinates
1982 • 53,055 citations
The rat brain in stereotaxic coordinates
1983 • 28,962 citations
Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C
1984 • 2,728 citations
A psychomotor stimulant theory of addiction.
1987 • 2,704 citations
Food reward: Brain substrates of wanting and liking
1996 • 1,831 citations
Modulation of memory fields by dopamine Dl receptors in prefrontal cortex
1995 • 1,600 citations
CREB AND MEMORY
1998 • 1,421 citations
Basic Neurochemistry: Molecular, Cellular, and Medical Aspects
1989 • 1,360 citations
Genetic Demonstration of a Role for PKA in the Late Phase of LTP and in Hippocampus-Based Long-Term Memory
1997 • 1,228 citations
Effects of cAMP Simulate a Late Stage of LTP in Hippocampal CA1 Neurons
1993 • 1,212 citations
Neurobehavioural mechanisms of reward and motivation
1996 • 1,177 citations
Models of Information Processing in the Basal Ganglia
1994 • 1,152 citations
The patterns of afferent innervation of the core and shell in the “Accumbens” part of the rat ventral striatum: Immunohistochemical detection of retrogradely transported fluoro‐gold
1993 • 1,084 citations
On the significance of subterritories in the “accumbens” part of the rat ventral striatum
1992 • 1,022 citations
The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurones
1990 • 1,021 citations
Memory Formation: The Sequence of Biochemical Events in the Hippocampus and Its Connection to Activity in Other Brain Structures
1997 • 981 citations
NMDA-receptor-dependent synaptic plasticity: multiple forms and mechanisms
1993 • 893 citations
Cross Talk between ERK and PKA Is Required for Ca2+ Stimulation of CREB-Dependent Transcription and ERK Nuclear Translocation
1998 • 885 citations
Synaptic plasticity in the hippocampus: LTP and LTD
1994 • 653 citations
The role of dopamine in drug abuse viewed from the perspective of its role in motivation
1995 • 632 citations
Induction of CRE-Mediated Gene Expression by Stimuli That Generate Long-Lasting LTP in Area CA1 of the Hippocampus
1996 • 594 citations
The involvement of nucleus accumbens dopamine in appetitive and aversive motivation
1994 • 580 citations
Neuromodulatory actions of dopamine in the neostriatum are dependent upon the excitatory amino acid receptor subtypes activated.
1993 • 552 citations
Spatially Resolved Dynamics of cAMP and Protein Kinase A Subunits in Aplysia Sensory Neurons
1993 • 549 citations
Different Training Procedures Recruit Either One or Two Critical Periods for Contextual Memory Consolidation, Each of Which Requires Protein Synthesis and PKA
1998 • 523 citations
Synthesis of β-Tubulin, Actin, and Other Proteins in Axons of Sympathetic Neurons in Compartmented Cultures
1999 • 509 citations
Involvement of hippocampal cAMP/cAMP-dependent protein kinase signaling pathways in a late memory consolidation phase of aversively motivated learning in rats
1997 • 500 citations
Memory Consolidation for Contextual and Auditory Fear Conditioning Is Dependent on Protein Synthesis, PKA, and MAP Kinase
1999 • 403 citations
Neuronal adaptation to amphetamine and dopamine: Molecular mechanisms of prodynorphin gene regulation in rat striatum
1995 • 364 citations
Dopamine and N-Methyl-D- Aspartate Receptor Interactions in the Neostriatum
1998 • 358 citations
Involvement of cAMP-Dependent Protein Kinase in the Nucleus Accumbens in Cocaine Self-Administration and Relapse of Cocaine-Seeking Behavior
1998 • 325 citations
Coincident Activation of NMDA and Dopamine D1Receptors within the Nucleus Accumbens Core Is Required for Appetitive Instrumental Learning
2000 • 324 citations
A Dopamine/D1 Receptor/Protein Kinase A/Dopamine- and cAMP-Regulated Phosphoprotein (Mr32 kDa)/Protein Phosphatase-1 Pathway Regulates Dephosphorylation of the NMDA Receptor
1998 • 322 citations
Dopamine reverses the depression of rat corticostriatal synapses which normally follows high-frequency stimulation of cortex In vitro
1996 • 299 citations
Synaptic relationships between dopaminergic afferents and cortical or thalamic input in the sensorimotor territory of the striatum in monkey
1994 • 297 citations
Response-reinforcement learning is dependent on N -methyl- <scp>d</scp> -aspartate receptor activation in the nucleus accumbens core
1997 • 295 citations
Amphetamine and Dopamine-Induced Immediate Early Gene Expression in Striatal Neurons Depends on Postsynaptic NMDA Receptors and Calcium
1996 • 287 citations
Maintenance of late-phase LTP is accompanied by PKA-dependent increase in AMPA receptor synthesis
1998 • 230 citations
Postsynaptic integration of glutamatergic and dopaminergic signals in the striatum
1994 • 185 citations
Excitatory amino acids and drugs of abuse: a role for N-methyl-d-aspartate receptors in drug tolerance, sensitization and physical dependence
1995 • 178 citations
A mechanistic and kinetic analysis of the interactions of the diastereoisomers of adenosine 3′,5′-(cyclic)phosphorothioate with purified cyclic AMP-dependent protein kinase
1988 • 171 citations
Impaired hippocampal plasticity in mice lacking the Cbeta1 catalytic subunit of cAMP-dependent protein kinase.
1996 • 169 citations
Hippocampal cGMP and cAMP are differentially involved in memory processing of inhibitory avoidance learning
1996 • 163 citations
Cellular Models of Reinforcement
1994 • 143 citations
Opposite Modulation of Opiate Withdrawal Behaviors on Microinfusion of a Protein Kinase A Inhibitor Versus Activator into the Locus Coeruleus or Periaqueductal Gray
1997 • 129 citations
Drugs acting upon the cyclic adenosine monophosphate/ protein kinase A signalling pathway modulate memory consolidation when given late after training into rat hippocampus but not amygdala
1997 • 126 citations
Activation of cAMP-Dependent Protein Kinase A in Prefrontal Cortex Impairs Working Memory Performance
1999 • 115 citations
N-methyl-D-aspartate receptor-dependent plasticity within a distributed corticostriatal network mediates appetitive instrumental learning.
2000 • 113 citations
Genes, nerve cells, and the remembrance of things past
1989 • 99 citations
N-methyl-D-aspartate receptor-dependent plasticity within a distributed corticostriatal network mediates appetitive instrumental learning.
2000 • 98 citations
Late and prolonged post-training memory modulation in entorhinal and parietal cortex by drugs acting on the cAMP/protein kinase A signalling pathway
1997 • 77 citations
Protein Kinase Inhibitors: Probes for the Functions of Protein Phosphorylation
1991 • 76 citations
Elements of the Intrinsic Organization and Information Processing in the Neostriatum
1994 • 57 citations
Possible involvement of protein kinases in physical dependence on opioids: studies using protein kinase inhibitors, H-7 and H-8
1995 • 55 citations
Excitatory interaction between glutamate receptors and protein kinases
1994 • 55 citations
Stimulators of the cAMP Cascade Reverse Amnesia Induced by Intra-amygdala but Not Intrahippocampal KN-62 Administration
1999 • 39 citations
Involvement of mechanisms dependent on NMDA receptors, nitric oxide and protein kinase A in the hippocampus but not in the caudate nucleus in memory
1997 • 39 citations
Conditioned locomotion in rats following amphetamine infusion into the nucleus accumbens: blockade by coincident inhibition of protein kinase A
2000 • 34 citations
Injection of the protein kinase inhibitor H7 into the A10 dopamine region blocks the acute responses to cocaine: Behavioral and in vivo microdialysis studies
1993 • 34 citations
Distinct interactions between Ca2+/calmodulin and neurotransmitter stimulation of adenylate cyclase in striatum and hippocampus
1988 • 25 citations
Agents that affect cAMP levels or protein kinase A activity modulate memory consolidation when injected into rat hippocampus but not amygdala
1997 • 20 citations
Blockade of neurotensin-induced motor activity by inhibition of protein kinase
1994 • 11 citations