Isoforms of SLC26A6 mediate anion transport and have functional PDZ interaction domains

Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains

1997 • 1,371 citations

Prestin is the motor protein of cochlear outer hair cells

2000 • 1,285 citations

Pendred syndrome is caused by mutations in a putative sulphate transporter gene (PDS)

1997 • 1,123 citations

The diastrophic dysplasia gene encodes a novel sulfate transporter: Positional cloning by fine-structure linkage disequilibrium mapping

1994 • 751 citations

The Pendred syndrome gene encodes a chloride-iodide transport protein

1999 • 565 citations

Pendrin, encoded by the Pendred syndrome gene, resides in the apical region of renal intercalated cells and mediates bicarbonate secretion

2001 • 526 citations

An Apical PDZ Protein Anchors the Cystic Fibrosis Transmembrane Conductance Regulator to the Cytoskeleton

1998 • 472 citations

Intracellular Anions as the Voltage Sensor of Prestin, the Outer Hair Cell Motor Protein

2001 • 469 citations

PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane

1999 • 469 citations

Mutations of the Down–regulated in adenoma (DRA) gene cause congenital chloride diarrhoea

1996 • 408 citations

Accessory Protein Facilitated CFTR-CFTR Interaction, a Molecular Mechanism to Potentiate the Chloride Channel Activity

2000 • 306 citations

Pendrin: an apical Cl⁻/OH⁻/HCO₃⁻exchanger in the kidney cortex

2001 • 292 citations

Mouse Down-regulated in Adenoma (DRA) Is an Intestinal Cl−/HCO3− Exchanger and Is Up-regulated in Colon of Mice Lacking the NHE3 Na+/H+Exchanger

1999 • 273 citations

Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells

2001 • 242 citations

Identification of an apical Cl⁻/HCO₃⁻exchanger in the small intestine

2002 • 235 citations

E3KARP Mediates the Association of Ezrin and Protein Kinase A with the Cystic Fibrosis Transmembrane Conductance Regulator in Airway Cells

2000 • 215 citations

Regulation of cystic fibrosis transmembrane conductance regulator single-channel gating by bivalent PDZ-domain-mediated interaction

2001 • 212 citations

Molecular characterization of the murine Slc26a6 anion exchanger: functional comparison with Slc26a1

2002 • 211 citations

Functional Characterization of Three Novel Tissue-specific Anion Exchangers SLC26A7, -A8, and -A9

2002 • 210 citations

Mapping of Five New Putative Anion Transporter Genes in Human and Characterization of SLC26A6, A Candidate Gene for Pancreatic Anion Exchanger

2000 • 207 citations

Functional expression cloning of the canalicular sulfate transport system of rat hepatocytes.

1994 • 201 citations

Cystic Fibrosis Transmembrane Conductance Regulator Regulates Luminal Cl−/HCO3−Exchange in Mouse Submandibular and Pancreatic Ducts

1999 • 196 citations

Human pendrin expressed in Xenopus laevis oocytes mediates chloride/formate exchange

2000 • 181 citations

Yes-Associated Protein 65 Localizes P62c-Yes to the Apical Compartment of Airway Epithelia by Association with Ebp50

1999 • 180 citations

The PDZ interacting domain of CFTR is required for functional expression in the apical plasma membrane

2000 • 170 citations

Downregulated in adenoma gene encodes a chloride transporter defective in congenital chloride diarrhea

1999 • 168 citations

Congenital Chloride Diarrhea

1982 • 155 citations

Specificity of Anion Exchange Mediated by Mouse Slc26a6

2002 • 149 citations

The Down Regulated in Adenoma (dra) Gene Encodes an Intestine-specific Membrane Sulfate Transport Protein

1995 • 146 citations

The PDZ-interacting Domain of Cystic Fibrosis Transmembrane Conductance Regulator Is Required for Functional Expression in the Apical Plasma Membrane

2000 • 144 citations

Functional Analysis of Diastrophic Dysplasia Sulfate Transporter

1998 • 136 citations

Regulatory Interaction between the Cystic Fibrosis Transmembrane Conductance Regulator and HCO <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si2.gif"><mml:msubsup><mml:mrow /><mml:mrow><mml:mn>3</mml:mn></mml:mrow><mml:mrow><mml:mo>−</mml:mo></mml:mrow></mml:msubsup></mml:math> Salvage Mechanisms in Model Systems and the Mouse Pancreatic Duct

2001 • 109 citations

Downregulated in adenoma and putative anion transporter are regulated by CFTR in cultured pancreatic duct cells

2001 • 102 citations

Prestin topology: localization of protein epitopes in relation to the plasma membrane

2001 • 101 citations

Tat1, a Novel Sulfate Transporter Specifically Expressed in Human Male Germ Cells and Potentially Linked to RhoGTPase Signaling

2001 • 94 citations

The Band 3-Related AE Anion Exchanger Gene Family

1994 • 93 citations

A PDZ-binding motif is essential but not sufficient to localize the C terminus of CFTR to the apical membrane

2001 • 92 citations

III. Congenital chloride diarrhea

1999 • 91 citations

CYSTIC FIBROSIS OF THE PANCREAS

1968 • 87 citations

Cloning and Characterization of SLC26A6, a Novel Member of the Solute Carrier 26 Gene Family

2001 • 86 citations

Expression of rat renal sulfate transport systems in Xenopus laevis oocytes. Functional characterization and molecular identification.

1994 • 72 citations

Lacunar Infarcts: A 1-Year Clinical and MRI Follow-Up Study

1994 • 45 citations

Cloning of the Full-Length Coding Sequence of Rat Liver-Specific Organic Anion Transporter-1 (rlst-1) and a Splice Variant and Partial Characterization of the Rat lst-1 Gene

2000 • 39 citations