Pendrin, encoded by the Pendred syndrome gene, resides in the apical region of renal intercalated cells and mediates bicarbonate secretion

[1] Preparation of monoclonal antibodies: Strategies and procedures

1981 • 1,787 citations

Pendred syndrome is caused by mutations in a putative sulphate transporter gene (PDS)

1997 • 1,123 citations

Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger

1998 • 839 citations

Cellular and subcellular immunolocalization of vasopressin-regulated water channel in rat kidney.

1993 • 709 citations

The Pendred syndrome gene encodes a chloride-iodide transport protein

1999 • 565 citations

Stress protein systems of mammalian cells

1986 • 564 citations

Targeted disruption of mouse Pds provides insight about the inner-ear defects encountered in Pendred syndrome

2001 • 407 citations

Regulation of collecting duct water channel expression by vasopressin in Brattleboro rat.

1994 • 395 citations

Pendrin, the Protein Encoded by the Pendred Syndrome Gene (PDS), Is an Apical Porter of Iodide in the Thyroid and Is Regulated by Thyroglobulin in FRTL-5 Cells

2000 • 389 citations

Subtypes of intercalated cells in rat kidney collecting duct defined by antibodies against erythroid band 3 and renal vacuolar H+-ATPase.

1989 • 378 citations

Localization of a proton-pumping ATPase in rat kidney.

1988 • 343 citations

Expression pattern of the mouse ortholog of the Pendred’s syndrome gene ( Pds ) suggests a key role for pendrin in the inner ear

1999 • 300 citations

Pendrin: an apical Cl⁻/OH⁻/HCO₃⁻exchanger in the kidney cortex

2001 • 292 citations

Free radical injury to skeletal muscles of young, adult, and old mice

1990 • 283 citations

Structural-functional relationships along the distal nephron

1986 • 270 citations

Aquaporin-6: An intracellular vesicle water channel protein in renal epithelia

1999 • 249 citations

Molecular Analysis of the Pds Gene in Pendred Syndrome (Sensorineural Hearing Loss and Goitre)

1998 • 240 citations

The Band 3-Related Anion Exchanger (AE) Gene Family

1991 • 233 citations

Two types of collecting duct mitochondria-rich (intercalated) cells: lectin and band 3 cytochemistry

1986 • 212 citations

Selectively amplified expression of an isoform of the vacuolar H(+)-ATPase 56-kilodalton subunit in renal intercalated cells.

1992 • 212 citations

Two Frequent Missense Mutations in Pendred Syndrome

1998 • 188 citations

Human pendrin expressed in Xenopus laevis oocytes mediates chloride/formate exchange

2000 • 181 citations

Function and Regulation of Collecting Duct Intercalated Cells

1993 • 179 citations

Bicarbonate transport by rabbit cortical collecting tubules. Effect of acid and alkali loads in vivo on transport in vitro.

1977 • 174 citations

Intercalated Cell Subtypes in Connecting Tubule and Cortical Collecting Duct of Rat and Mouse

1999 • 171 citations

Autoregulation of thyroid-specific gene transcription by thyroglobulin

1998 • 145 citations

A New Member of the HCO <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si1.gif"><mml:msubsup><mml:mrow /><mml:mrow><mml:mn>3</mml:mn></mml:mrow><mml:mrow><mml:mo>−</mml:mo></mml:mrow></mml:msubsup></mml:math>Transporter Superfamily Is an Apical Anion Exchanger of β-Intercalated Cells in the Kidney

2001 • 145 citations

Chloride/formate exchange with formic acid recycling: a mechanism of active chloride transport across epithelial membranes.

1985 • 130 citations

Bicarbonate secretion and chloride absorption by rabbit cortical collecting ducts. Role of chloride/bicarbonate exchange.

1985 • 123 citations

Expression of Pendrin and the Pendred Syndrome (PDS) Gene in Human Thyroid Tissues*

2000 • 120 citations

Identification of distinct subpopulations of intercalated cells in the mouse collecting duct.

1996 • 114 citations

Plasticity in epithelial polarity of renal intercalated cells: targeting of the H(+)-ATPase and band 3

1996 • 104 citations

Immunologic evidence that vacuolar H+ ATPases with heterogeneous forms of Mr = 31,000 subunit have different membrane distributions in mammalian kidney.

1992 • 98 citations

Electrophysiological identification of alpha- and beta-intercalated cells and their distribution along the rabbit distal nephron segments.

1990 • 95 citations

Morphological heterogeneity of the rabbit collecting duct

1988 • 95 citations

Ammonia and bicarbonate transport by rat cortical collecting ducts perfused in vitro

1985 • 88 citations

The apical Cl/HCO3 exchanger of beta intercalated cells

1993 • 65 citations

Differential expression of AE1 in renal HCO3-secreting and -reabsorbing intercalated cells.

1994 • 62 citations

NH+4 augments net acid secretion by a ouabain-sensitive mechanism in isolated perfused inner medullary collecting ducts

1996 • 55 citations

Net acid transport by isolated perfused inner medullary collecting ducts

1990 • 54 citations

Fluorescent characterization of collecting duct cells: a second H+-secreting type

1988 • 48 citations

Quantitation of total carbon dioxide in nanoliter samples by flow-through fluorometry

1990 • 29 citations

Functional characterization of alpha- and beta-intercalated cell types in rabbit cortical collecting duct

1991 • 28 citations

Functional consequences of mutations in the transmembrane domain and the carboxy-terminus of the murine AE1 anion exchanger

1997 • 25 citations

Cortical collecting duct bicarbonate secretion.

1991 • 22 citations

Acid-base transport in the inner medullary collecting duct.

1990 • 18 citations

Mechanism of Ammonia Secretion by Rabbit Cortical Collecting Ducts

2015 • 3 citations