Involvement of N-terminal-extended Form of Sphingosine Kinase 2 in Serum-dependent Regulation of Cell Proliferation and Apoptosis

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

1996 • 1,493 citations

Sphingosine 1-phosphate signalling in mammalian cells

2000 • 698 citations

Molecular Cloning and Functional Characterization of a Novel Mammalian Sphingosine Kinase Type 2 Isoform

2000 • 654 citations

Molecular Cloning and Functional Characterization of Murine Sphingosine Kinase

1998 • 528 citations

Sphingosine Kinase Expression Increases Intracellular Sphingosine-1-Phosphate and Promotes Cell Growth and Survival

1999 • 516 citations

Sphingosine 1-phosphate signalling in mammalian cells

2000 • 458 citations

Phosphorylation of the Immunomodulatory Drug FTY720 by Sphingosine Kinases

2003 • 427 citations

Sphingosine Kinase 2 Is a Nuclear Protein and Inhibits DNA Synthesis

2003 • 407 citations

Sphingosine Kinase Type 2 Is a Putative BH3-only Protein That Induces Apoptosis

2003 • 352 citations

The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2

2003 • 300 citations

Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway.

1994 • 273 citations

Activation of Sphingosine Kinase by Tumor Necrosis Factor-α Inhibits Apoptosis in Human Endothelial Cells

1999 • 270 citations

Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling

2004 • 261 citations

Functional Roles of Sphingosine, Sphingosine 1-Phosphate, and Methylsphingosines: In Regard to Membrane Sphingolipid Signaling Pathways

1997 • 134 citations

Sphingosine-1-phosphate and lipid phosphohydrolases

2002 • 109 citations

Molecular diversity of sphingolipid signalling

1997 • 108 citations

Identification and Characterization of RPK118, a Novel Sphingosine Kinase-1-binding Protein

2002 • 92 citations

Positive Modulation of IL-12 Signaling by Sphingosine Kinase 2 Associating with the IL-12 Receptor β1 Cytoplasmic Region

2003 • 64 citations

δ-Catenin/NPRAP (neural plakophilin-related armadillo repeat protein) interacts with and activates sphingosine kinase 1

2004 • 50 citations

Effect of a membrane-targeted sphingosine kinase 1 on cell proliferation and survival

2005 • 21 citations