Binding of Zinc Finger Protein ZPR1 to the Epidermal Growth Factor Receptor

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

A novel genetic system to detect protein–protein interactions

1989 • 6,022 citations

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1994 • 3,219 citations

Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine

1995 • 2,238 citations

Mammalian Ras interacts directly with the serine/threonine kinase raf

1993 • 1,983 citations

SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins

1991 • 1,931 citations

Independent Human MAP-Kinase Signal Transduction Pathways Defined by MEK and MKK Isoforms

1995 • 1,562 citations

Growth factor signaling by receptor tyrosine kinases

1992 • 1,450 citations

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

1992 • 1,358 citations

Crystal structure of the tyrosine kinase domain of the human insulin receptor

1994 • 1,071 citations

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

1994 • 1,043 citations

The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family

1995 • 990 citations

SH2 and SH3 domains: From structure to function

1992 • 977 citations

Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody.

1983 • 792 citations

Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails.

1992 • 609 citations

An Alternative to SH2 Domains for Binding Tyrosine-Phosphorylated Proteins

1994 • 501 citations

Involvement of CRAF1, a relative of TRAF, in CD40 signaling

1995 • 454 citations

A novel RING finger protein interacts with the cytoplasmic domain of CD40.

1994 • 345 citations

The EGF receptor is an actin-binding protein.

1992 • 248 citations

PTB Domain Binding to Signaling Proteins Through a Sequence Motif Containing Phosphotyrosine

1995 • 245 citations

Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase.

1992 • 166 citations

Independent mechanisms account for the regulation by protein kinase C of the epidermal growth factor receptor affinity and tyrosine-protein kinase activity.

1988 • 161 citations

LIM domain recognition of a tyrosine-containing tight turn.

1994 • 119 citations

Mechanism of Phosphorylation of the Epidermal Growth Factor Receptor at Threonine 669

1989 • 93 citations

Monoclonal anti-histone autoantibodies derived from murine models of lupus.

1984 • 64 citations

Evidence for the potentiation of epidermal growth factor receptor tyrosine kinase activity by association with the detergent-insoluble cellular cytoskeleton: analysis of intact and carboxy-terminally truncated receptors.

1993 • 38 citations

The calpain cleavage sites in the epidermal growth factor receptor kinase domain

1994 • 37 citations

Modulation of epidermal growth factor receptor interaction with the detergent-insoluble cytoskeleton and its effects on receptor tyrosine kinase activity.

1995 • 37 citations

Epidermal growth factor treatment of A431 cells alters the binding capacity and electrophoretic mobility of the cytoskeletally associated epidermal growth factor receptor

1991 • 21 citations