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Hepatic P450 Expression in Hypothyroid Rats: Differential Responsiveness of Male-Specific P450 Forms 2a (IIIA2), 2c (IIC11), and RLM2 (IIA2) to Thyroid Hormone

Data up to Jan 2025

Published1991
Citations55
References33

Total Citations Per Year

Abstract

References (33)

The P450 Superfamily: Update on New Sequences, Gene Mapping, and Recommended Nomenclature

1991 • 1,092 citations

Sexual Dimorphism in the Control of Growth Hormone Secretion*

1985 • 749 citations

Regulation of gene expression by thyroid hormone.

1988 • 317 citations

Sex Steroid Induced Changes in Hepatic Enzymes

1983 • 314 citations

Hormonal and developmental regulation of expression of the hepatic microsomal steroid 16 alpha-hydroxylase cytochrome P-450 apoprotein in the rat.

1985 • 261 citations

Suppression of levels of phenobarbital-inducible rat liver cytochrome P-450 by pituitary hormone.

1987 • 177 citations

Stimulation of hepatic mitochondrial alpha-glycerophosphate dehydrogenase and malic enzyme by L-triiodothyronine. Characteristics of the response with specific nuclear thyroid hormone binding sites fully saturated.

1977 • 151 citations

Methimazole Pharmacology in Man: Studies Using a Newly Developed Radioimmunoassay for Methimazole*

1984 • 139 citations

Adult male-specific and neonatally programmed rat hepatic P-450 forms RLM2 and 2a are not dependent on pulsatile plasma growth hormone for expression.

1988 • 138 citations

Structural analysis and specific expression of microsomal cytochrome P-450(M-1) mRNA in male rat livers.

1987 • 108 citations

Decreased hypothalamic growth hormone-releasing hormone content and pituitary responsiveness in hypothyroidism.

1986 • 103 citations

Effect of Growth Hormone and Ectopic Transplantation of Pituitary Gland on Sex-Specific Forms of Cytochrome P-450 and Testosterone and Drug Oxidations in Rat Liver1

1986 • 101 citations

Nyctohemeral and Sex-Related Variations in Plasma Thyrotropin, Thyroxine, and Triiodothyronine

1975 • 96 citations

Pretranslational regulation of sex-dependent testosterone hydroxylases by growth hormone in mouse liver.

1986 • 89 citations

Induction of Hepatic Receptors for Growth Hormone (GH) and Prolactin by GH Infusion Is Sex Independent*

1984 • 87 citations

Pituitary Regulation of the Male-Specific Steroid 6β-Hydroxylase P-450 2a (gene product IIIA2) in Adult Rat Liver. Suppressive Influence of Growth Hormone and Thyroxine Acting at a Pretranslational Level

1990 • 86 citations

Hepatic P-450 cholesterol 7 alpha-hydroxylase. Regulation in vivo at the protein and mRNA level in response to mevalonate, diurnal rhythm, and bile acid feedback.

1990 • 85 citations

Hypophysectomy differentially alters P-450 protein levels and enzyme activities in rat liver: pituitary control of hepatic NADPH cytochrome P-450 reductase.

1989 • 75 citations

Gene conversion and differential regulation in the rat P-450 IIA gene subfamily. Purification, catalytic activity, cDNA and deduced amino acid sequence, and regulation of an adult male-specific hepatic testosterone 15 alpha-hydroxylase.

1988 • 66 citations

Feminization of rat hepatic P-450 expression by cisplatin. Evidence for perturbations in the hormonal regulation of steroid-metabolizing enzymes.

1988 • 60 citations

The Influence of Thyroid Hormone Status on the Hypothalamo-Hypophyseal Growth Hormone Axis*

1990 • 60 citations

Pretranslational control by thyroid hormone of rat liver steroid 5 alpha-reductase and comparison to the thyroid dependence of two growth hormone-regulated CYP2C mRNAs.

1990 • 58 citations

Alterations of Human Growth Hormone Binding by Rat Liver Membranes during Hypo- and Hyperthyroidism

1990 • 55 citations

Hormonal Regulation of Male-specific Rat Hepatic Cytochrome P-450g (P-450IIC13) by Androgens and the Pituitary

1989 • 55 citations

Thyroid hormone and activities of drug-metabolizing enzymes and electron transport systems of rat liver microsomes.

1968 • 54 citations

Sex differences in binding of human growth hormone to isolated rat hepatocytes.

1976 • 54 citations

Identification of cytochrome P450a (P450IIA1) as the principal testosterone 7α-hydroxylase in rat liver microsomes and its regulation by thyroid hormones

1989 • 51 citations

Thyroid hormone suppression of hepatic levels of phenobarbital-inducible P-450b AND P-450e and other neonatal P-450S in hypophysectomized rats

1989 • 44 citations

Hormonal Regulation of Levels of the Messenger RNA Encoding Hepatic P450 2c (IIC11), a Constitutive Male-Specific Form of Cytochrome P450

1990 • 35 citations

Effects of Thyroid Hormone Deficiency and Replacement on Rat Hypothalamic Growth Hormone (GH)-Releasing Hormone Gene Expressionin VivoAre Mediated by GH

1990 • 33 citations

Sex- and substrate-dependent effects of the thyroid gland on drug metabolism in the rat

1983 • 14 citations

Thyroid Hormone Regulation of Heme Synthesis in Rat Liver*

1988 • 8 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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