MK-801 blocks NMDA receptor-mediated synaptic transmission and long term potentiation in rat hippocampal slices

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

1986 • 3,586 citations

Excitatory amino acids in synaptic transmission in the Schaffer collateral‐commissural pathway of the rat hippocampus.

1983 • 2,376 citations

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

1986 • 1,814 citations

NMDA receptors - their role in long-term potentiation

1987 • 1,177 citations

Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil

1987 • 647 citations

Possible Therapeutic Applications of Antagonists of Excitatory Amino acid Neurotransmitters

1985 • 558 citations

Anticonvulsant activity of (+)‐5‐methyl‐10, 11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

1982 • 496 citations

L-Glutamate has higher affinity than other amino acids for [3H]-D-AP5 binding sites in rat brain membranes

1984 • 293 citations

Magnesium ions block an N-methyl-d-aspartate receptor-mediated component of synaptic transmission in rat hippocampus

1985 • 222 citations

Effects of phencyclidine, SKF 10,047 and related psychotomimetic agents on N‐methyl‐<scp>d</scp>‐aspartate receptor mediated synaptic responses in rat hippocampal slices

1987 • 170 citations

Elimination of long-term potentiation in the hippocampus by phencyclidine and ketamine

1983 • 100 citations

Characterization of an N-methyl-d-aspartate receptor component of synaptic transmission in rat hippocampal slices

1987 • 78 citations