Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

1995 • 93,704 citations

Basic local alignment search tool

1990 • 87,358 citations

The Sequence Alignment/Map format and SAMtools

2009 • 54,537 citations

Fast and accurate short read alignment with Burrows–Wheeler transform

2009 • 51,582 citations

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

2008 • 13,725 citations

Circos: An information aesthetic for comparative genomics

2009 • 9,656 citations

Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis

2007 • 5,258 citations

Patterns of somatic mutation in human cancer genomes

2007 • 2,975 citations

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

2009 • 2,777 citations

International network of cancer genome projects

2010 • 2,233 citations

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

2012 • 1,883 citations

A comprehensive catalogue of somatic mutations from a human cancer genome

2009 • 1,668 citations

ARID1AMutations in Endometriosis-Associated Ovarian Carcinomas

2010 • 1,552 citations

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

2011 • 1,469 citations

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

2011 • 1,218 citations

Integration of Hepatitis B Virus DNA into the Genome of Liver Cells in Chronic Liver Disease and Hepatocellular Carcinoma

1981 • 715 citations

The Genetic Landscape of the Childhood Cancer Medulloblastoma

2010 • 695 citations

Genetics of hepatocellular tumors

2006 • 310 citations

Determinants of protein function revealed by combinatorial entropy optimization

2007 • 308 citations

Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene

2003 • 308 citations

High-resolution characterization of a hepatocellular carcinoma genome

2011 • 282 citations

The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients

2012 • 281 citations

Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types

2011 • 278 citations

Mig6 is a negative regulator of EGF receptor–mediated skin morphogenesis and tumor formation

2006 • 259 citations

A tumor suppressive coactivator complex of p53 containing ASC-2 and histone H3-lysine-4 methyltransferase MLL3 or its paralogue MLL4

2009 • 208 citations

Whole-genome sequencing and comprehensive variant analysis of a Japanese individual using massively parallel sequencing

2010 • 114 citations

Identification of human cancer-related genes by naturally occurring Hepatitis B Virus DNA tagging

2001 • 105 citations

Studying copy number variations using a nanofluidic platform

2008 • 100 citations

Mitogen-inducible gene-6 is a negative regulator of epidermal growth factor receptor signaling in hepatocytes and human hepatocellular carcinoma

2009 • 78 citations

WW domain containing E3 ubiquitin protein ligase 1 targets the full-length ErbB4 for ubiquitin-mediated degradation in breast cancer

2009 • 74 citations

A segmental maximum a posteriori approach to genome-wide copy number profiling

2008 • 36 citations

Integrated state of subgenomic fragments of hepatitis B virus DNA in hepatocellular carcinoma from mainland China.

1987 • 36 citations