Phenotypic analysis of retinal leukocyte infiltration during combined cyclosporin a and nasal antigen administration of retinal antigens: delay and inhibition of macrophage and granulocyte infiltration

Peripheral deletion of antigen-reactive T cells in oral tolerance

1995 • 775 citations

Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, and prostaglandin E expression in the brain.

1992 • 726 citations

Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4+ T cells compared.

1995 • 622 citations

Double-Blind Pilot Trial of Oral Tolerization with Myelin Antigens in Multiple Sclerosis

1993 • 592 citations

Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages.

1990 • 511 citations

Inhibition of S-antigen induced experimental autoimmune uveoretinitis by oral induction of tolerance with S-antigen.

1990 • 288 citations

Oral tolerance in myelin basic protein T-cell receptor transgenic mice: suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cells.

1996 • 260 citations

Direct evidence for anergy in T lymphocytes tolerized by oral administration of ovalbumin

1993 • 233 citations

Long-term remission of intractable systemic vasculitis with monoclonal antibody therapy

1993 • 205 citations

Synergy between anti-CD4 and anti-tumor necrosis factor in the amelioration of established collagen-induced arthritis.

1994 • 188 citations

Oral tolerance in experimental autoimmune uveoretinitis. Distinct mechanisms of resistance are induced by low dose vs high dose feeding protocols.

1993 • 184 citations

Experimental allergic encephalomyelitis in the absence of a classical delayed-type hypersensitivity reaction. Severe paralytic disease correlates with the presence of interleukin 2 receptor-positive cells infiltrating the central nervous system.

1987 • 182 citations

CD4⁺ but not CD8⁺T cells are required for the induction of oral tolerance

1995 • 153 citations

Inhibition of tumor necrosis factor activity minimizes target organ damage in experimental autoimmune uveoretinitis despite quantitatively normal activated T cell traffic to the retina

1996 • 145 citations

Macrophage-inactivating IL-13 suppresses experimental autoimmune encephalomyelitis in rats.

1994 • 135 citations

Flow cytometric identification of a minority population of MHC class II positive cells in the normal rat retina distinct from CD45lowCD11b/c+CD4low parenchymal microglia.

1995 • 112 citations

Interleukin-2 treatment potentiates induction of oral tolerance in a murine model of autoimmunity.

1994 • 112 citations

Generation and characterization of purified adherent lymphokine-activated killer cells in mice.

1989 • 106 citations

Nasal administration of retinal antigens suppresses the inflammatory response in experimental allergic uveoretinitis. A preliminary report of intranasal induction of tolerance with retinal antigens.

1993 • 87 citations

In situ hybridization for interleukin 2 and interleukin 2 receptor mRNA in T cells activated in the presence or absence of cyclosporin A.

1988 • 86 citations

Recruitment of antigen-nonspecific cells plays a pivotal role in the pathogenesis of a T cell-mediated organ-specific autoimmune uveoretinitis

1993 • 80 citations

Immunomodulation of experimental autoimmune uveoretinitis: A model of tolerance induction with retinal antigens

1994 • 73 citations

Intranasal administration of retinal antigens suppresses retinal antigen-induced experimental autoimmune uveoretinitis.

1994 • 60 citations

Identification of Two Subpopulations of Rat Monocytes Expressing Disparate Molecular Forms and Quantities of CD43

1995 • 54 citations

Inhibition of Experimental Autoimmune Uveoretinitis by Oral Administration of S-Antigen and Synthetic Peptides

1992 • 46 citations

Experimental approaches to specific immunotherapies in autoimmune disease: future treatment of endogenous posterior uveitis?

1995 • 30 citations

Interphotoreceptor retinoid binding protein is a potent tolerogen in Lewis rat: suppression of experimental autoimmune uveoretinitis is retinal antigen specific

1997 • 17 citations

Nasal administration of retinal antigens maintains immunosuppression of uveoretinitis in cyclosporin-a-treated lewis rats: Future treatment of endogenous posterior uveoretinitis?

1997 • 11 citations