Loss of heterozygosity on chromosome 9 in human breast cancer: Association with clinical variables and genetic changes at other chromosome regions

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1993 • 3,680 citations

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

1994 • 1,806 citations

Germline p16 mutations in familial melanoma

1994 • 1,241 citations

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

1994 • 1,142 citations

Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus

1994 • 860 citations

Deletion of p16 and p15 genes in brain tumors.

1994 • 416 citations

Frequent somatic mutation of the MTS1/CDK4I (multiple tumor suppressor/cyclin-dependent kinase 4 inhibitor) gene in esophageal squamous cell carcinoma.

1994 • 345 citations

p16 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma.

1994 • 324 citations

Frequent loss of chromosome 9p21-22 early in head and neck cancer progression.

1994 • 322 citations

Homozygous loss of the cyclin-dependent kinase 4-inhibitor (p16) gene in human leukemias

1994 • 164 citations

Frequent loss of chromosome 9 in human primary non-small cell lung cancer.

1994 • 136 citations

A region of homozygous deletion on chromosome 9p21-22 in primary nasopharyngeal carcinoma.

1994 • 128 citations

Allelotype study of esophageal carcinoma

1994 • 109 citations

Mutational analysis of CDKN2 (MTS1/p16ink4) in human breast carcinomas.

1994 • 107 citations

Localization of tumor suppressor loci on chromosome 9 in primary human renal cell carcinomas.

1995 • 99 citations

Chromosome 9p allelic loss and p16/CDKN2 in breast cancer and evidence of p16 inactivation in immortal breast epithelial cells.

1995 • 95 citations

Loss of heterozygosity at chromosome 11 in breast cancer: association of prognostic factors with genetic alterations

1995 • 84 citations

Homozygous deletion mapping at 9p21 in bladder carcinoma defines a critical region within 2cM of IFNA.

1994 • 61 citations

High frequency of allelic imbalance at chromosome region 16q22‐23 in human breast cancer: Correlation with high pgr and low s phase

1995 • 46 citations

Nuclear DNA analysis and prognosis in carcinoma of the thyroid gland

1994 • 27 citations

MAPPING OF CHROMOSOME-3 ALTERATIONS IN HUMAN BREAST-CANCER USING MICROSATELLITE PCR MARKERS - CORRELATION WITH CLINICAL-VARIABLES

1995 • 19 citations

LOSS OF HETEROZYGOSITY AT CHROMOSOME 6Q CORRELATES WITH TUMOR PROGRESSION AND PATIENT SURVIVAL

1995 • 8 citations