p16 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1993 • 3,680 citations

TP53 tumor suppressor gene: A model for investigating human mutagenesis

1992 • 584 citations

Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression.

1993 • 393 citations

Frequent somatic mutation of the MTS1/CDK4I (multiple tumor suppressor/cyclin-dependent kinase 4 inhibitor) gene in esophageal squamous cell carcinoma.

1994 • 345 citations

Homozygous deletions within human chromosome band 9p21 in melanoma.

1992 • 319 citations

Mutations in transcript isoforms of the neurofibromatosis 2 gene in multiple human tumour types

1994 • 228 citations

Recurrent deletions of specific chromosomal sites in 1p, 3p, 6q, and 9p in human malignant mesothelioma.

1993 • 163 citations

Chromosome 9 deletion mapping reveals interferon alpha and interferon beta-1 gene deletions in human glial tumors.

1991 • 149 citations

Homozygous loss of the interferon genes defines the critical region on 9p that is deleted in lung cancers.

1993 • 147 citations

Distinct deletions of chromosome 9p associated with melanoma versus glioma, lung cancer, and leukemia.

1994 • 58 citations

Deletion mapping of the short arm of chromosome 3 in human malignant mesothelioma

1994 • 43 citations